Jaguar Health Inc. has entered into a new note purchase agreement with Streeterville Capital, LLC. Under the agreement, Jaguar Health issued a secured promissory note with an original principal amount of $10.81 million, which includes an $800,000 original issue discount and $10,000 for the lender's transaction costs. On closing, Streeterville Capital paid $2 million directly to Jaguar Health, with an additional $8 million deposited into an account at Lakeside Bank owned by Jaguar Health's new subsidiary, JAGX Holdings, LLC. The terms of the agreement restrict Jaguar Health and its subsidiaries from incurring additional debt, granting security interests, or issuing equity in the subsidiary without the lender's prior written consent.