Annovis Bio Shares Rise After Positive Trial Data for Buntanetap

Dow Jones

2025/11/18

By Chris Wack

Annovis Bio shares were 43% higher, at $3.33, after the company reported positive results from a Phase 3 trial for buntanetap.

The late-stage clinical drug-platform company on Monday said the new data demonstrated a positive impact of amyloid copathology on cognitive outcomes in Parkinson's patients and the therapeutic efficacy of buntanetap.

The Malvern, Pa., company said that in its Phase 3 study in early Parkinson's patients, buntanetap halted cognitive decline across the overall patient population, with the greatest improvement observed in those with mild dementia.

Further analysis revealed that about 25% of patients exhibited amyloid co-pathology and experienced more pronounced cognitive decline over the course of the study, which Annovis said was counteracted and reversed by buntanetap.

Buntanetap treatment also led to significant cognitive improvement in Parkinson's patients with amyloid copathology.

Write to Chris Wack at chris.wack@wsj.com

(END) Dow Jones Newswires

November 17, 2025 12:43 ET (17:43 GMT)

Copyright (c) 2025 Dow Jones & Company, Inc.

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Company, Inc.\n</p>\n</font>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"ANVS","symbol_name":"Annovis Bio, Inc.","start_time":0,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","article_id":"2584689673","we_media_id":"106","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2584689673","pubTimestamp":1763401380,"columns":[{"name":"行業數據","id":30,"label_key":"dataReport"}],"sourceInfo":null,"weMediaInfo":{"media_name":"Dow Jones","introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"summary":"Annovis Bio shares were 43% higher, at $3.33, after the company reported positive results from a Phase 3 trial for buntanetap.The late-stage clinical drug-platform company on Monday said the new data demonstrated a positive impact of amyloid copathology on cognitive outcomes in Parkinson's patients and the therapeutic efficacy of buntanetap.The Malvern, Pa., company said that in its Phase 3 study in early Parkinson's patients, buntanetap halted cognitive decline across the overall patient population, with the greatest improvement observed in those with mild dementia.Further analysis revealed that about 25% of patients exhibited amyloid co-pathology and experienced more pronounced cognitive decline over the course of the study, which Annovis said was counteracted and reversed by buntanetap.Buntanetap treatment also led to significant cognitive improvement in Parkinson's patients with amyloid copathology.","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"ANVS":"Annovis Bio, Inc.","BK4139":"生物科技"},"translate_title":"Buntanetap试验数据积极后，Annovis Bio股价上涨","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"ANVS":1.5},"content_text":"By Chris Wack \n\n\n \n\n\nAnnovis Bio shares were 43% higher, at $3.33, after the company reported positive results from a Phase 3 trial for buntanetap. \n\n\n  The late-stage clinical drug-platform company on Monday said the new data demonstrated a positive impact of amyloid copathology on cognitive outcomes in Parkinson's patients and the therapeutic efficacy of buntanetap. \n\n\n  The Malvern, Pa., company said that in its Phase 3 study in early Parkinson's patients, buntanetap halted cognitive decline across the overall patient population, with the greatest improvement observed in those with mild dementia. \n\n\n  Further analysis revealed that about 25% of patients exhibited amyloid co-pathology and experienced more pronounced cognitive decline over the course of the study, which Annovis said was counteracted and reversed by buntanetap. \n\n\n  Buntanetap treatment also led to significant cognitive improvement in Parkinson's patients with amyloid copathology. \n\n\n \n\n\n  Write to Chris Wack at chris.wack@wsj.com \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 17, 2025 12:43 ET (17:43 GMT)\n\n\n  Copyright (c) 2025 Dow Jones & Company, Inc.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"dataReport","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":true,"code":"91000000","status":"200"}}}