European equities traded in the US as American depositary receipts opened the week little changed late Monday morning, edging 0.1% higher to 1,572.55 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biopharmaceutical company Cellectis (CLLS) and internet browser company Opera (OPRA), which advanced 10% and 2.4%, respectively. They were followed by medical device maker EDAP TMS (EDAP) and telecommunications company Nokia (NOK), which increased 1.7% and 1.5%, respectively.

The decliners from continental Europe were led by pharmaceutical company Novo Nordisk (NVO) and internet advertising firm Criteo (CRTO), which fell 7.8% and 1.4%, respectively. They were followed by oil and gas company Eni (E), which was down 1%.

From the UK and Ireland, the gainers were led by biopharmaceutical companies Mereo BioPharma Group (MREO) and Bicycle Therapeutics (BCYC), which rose 3.6% each. They were followed by biotech firm Trinity Biotech (TRIB) and biopharmaceutical company NuCana (NCNA), which were up 3.2% and 1.7%, respectively.

The decliners from the UK and Ireland were led by biopharmaceutical company Akari Therapeutics (AKTX), which dropped 5.2%. It was followed by utilities company National Grid (NGG) and communications company WPP (WPP), which lost 1.6% each.