Longeveron Stem Cell Therapy Reduces Neuroinflammation in Mild Alzheimer’s Disease, Phase 2 Trial Shows

Reuters
2025/12/02
Longeveron Stem Cell Therapy Reduces Neuroinflammation in Mild Alzheimer's Disease, Phase 2 Trial Shows

Longeveron Inc. announced new data from its Phase 2 placebo-controlled CLEAR-MIND clinical trial evaluating laromestrocel, a stem cell therapy, in patients with mild Alzheimer's disease. The results, presented at the 18th Clinical Trials on Alzheimer's Disease Conference (CTAD 2025), showed that treatment with laromestrocel was associated with a reduction in MRI-measured neuroinflammation across multiple key brain regions, including the hippocampus. The reduction in hippocampal neuroinflammation correlated with preservation of hippocampal volume and clinical outcomes. The findings support the continued development of laromestrocel for mild Alzheimer's disease.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Longeveron Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9593886-en) on December 01, 2025, and is solely responsible for the information contained therein.

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