Sellas Life Sciences Announces Positive Phase 2 Results for SLS009 Combination in Relapsed AML

Reuters

2025/12/08

Sellas Life Sciences Announces Positive Phase 2 Results for SLS009 Combination in Relapsed AML

Sellas Life Sciences Group Inc. announced positive results from its ongoing Phase 2 study evaluating SLS009, a selective CDK9 inhibitor, in combination with azacitidine (AZA) and venetoclax (VEN) for patients with relapsed or refractory acute myeloid leukemia with myelodysplastic syndrome-related changes (AML-MR) following prior VEN-based treatment. The results, presented at the 67th American Society of Hematology $(ASH)$ Annual Meeting in December 2025, showed a 46% overall response rate across all cohorts and a 58% overall response rate in patients with one prior line of therapy. The combination was reported to be safe and feasible, with no dose-limiting toxicities observed. The company plans to expand the study to evaluate SLS009 plus AZA/VEN in newly diagnosed AML with high-risk features in the first quarter of 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Sellas Life Sciences Group Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9597691-en) on December 07, 2025, and is solely responsible for the information contained therein.

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Sellas Life Sciences Group Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9597691-en) on December 07, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"SG9999014013.SGD","symbol_name":"United Global Durable Equities Fund Dis SGD","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251207:nNDL8SKKlH:1","article_id":"2589809491","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2589809491","pubTimestamp":1765148413,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Sellas Life Sciences Group Inc. announced positive results from its ongoing Phase 2 study evaluating SLS009, a selective CDK9 inhibitor, in combination with azacitidine  and venetoclax  for patients with relapsed or refractory acute myeloid leukemia with myelodysplastic syndrome-related changes  following prior VEN-based treatment. 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