Pfizer Reports HYMPAVZI Cuts Bleeds by 93% in Hemophilia Patients with Inhibitors

Reuters
12/07
Pfizer Reports HYMPAVZI Cuts Bleeds by 93% in Hemophilia Patients with Inhibitors

Pfizer Inc. has announced new clinical study results for HYMPAVZI, a treatment for adults and adolescents with hemophilia A or B who have developed inhibitors. The findings, presented at the 67th American Society of Hematology $(ASH)$ Annual Meeting and Exposition in Orlando and published in Blood, demonstrated that HYMPAVZI significantly reduced bleeding episodes and improved certain aspects of health-related quality of life with once-weekly subcutaneous administration. The safety profile was generally favorable, with no deaths or thromboembolic events reported; the most common adverse events included COVID-19, upper respiratory tract infection, fibrin D-dimer increase, and headache, mostly mild or moderate in severity. Pfizer has submitted these data to the U.S. Food and Drug Administration and European Medicines Agency for review. HYMPAVZI is currently approved in more than 40 countries for patients aged 12 years and older with hemophilia A or B without inhibitors.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Pfizer Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20251206552218) on December 06, 2025, and is solely responsible for the information contained therein.

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