Ascentage Pharma Says Bruton's Tyrosine Kinase-Targeted Protein Degrader Application Gets China Clearance

MT Newswires Live

02/06

Ascentage Pharma Group International (AAPG) said late Thursday that China Center for Drug Evaluation cleared the company's investigational new drug application for Bruton's tyrosine kinase-targeted protein degrader.

The candidate, APG-3288, is set to enter a clinical study in patients with relapsed/refractory hematologic malignancies.

The company said APG-3288 is currently under investigation and has not been approved by the US Food and Drug Administration.

Bruton's tyrosine kinase plays a key role in the activation, proliferation, and survival of B-cells.

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