Praxis Precision posts bigger Q4 loss as R&D costs grow

Reuters
02/19
Praxis Precision posts bigger Q4 loss as R&D costs grow

Overview

  • CNS biopharmaceutical firm reported wider Q4 net loss of $88.9 mln, with increased R&D expenses

  • Praxis submitted NDAs for ulixacaltamide and relutrigine to the FDA

  • Company raised $621 mln in January 2026 public offering, funding operations into 2028

Outlook

  • Praxis expects topline results for vormatrigine in Q2 2026

  • Company anticipates NDA submissions for vormatrigine and elsunersen by 2028

  • Praxis expects cash runway to fund operations into 2028

Result Drivers

  • NDA SUBMISSIONS - Praxis submitted NDAs for ulixacaltamide and relutrigine, positioning for commercial transition

  • COMMERCIAL PREPARATIONS - Co is preparing for the commercial launch of ulixacaltamide and relutrigine, including scaling its commercial organization

  • INCREASED R&D EXPENSES - Higher R&D costs driven by investments in Cerebrum and Solidus platforms

Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

Q4 EPS

-$3.50

Q4 Net Income

-$88.91 mln

Q4 Operating Expenses

$97.04 mln

Q4 Operating Income

-$97.04 mln

Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 14 "strong buy" or "buy", 1 "hold" and 1 "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy"

  • Wall Street's median 12-month price target for Praxis Precision Medicines Inc is $505.00, about 53.5% above its February 18 closing price of $328.93

Press Release: ID:nGNX1CpNyj

For questions concerning the data in this report, contact Estimates.Support@lseg.com. For any other questions or feedback, contact reuters.support@thomsonreuters.com.

(This story was created using Reuters automation and AI based on LSEG and company data. It was checked and edited by a Reuters journalist prior to publication.)

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