Structure Stock Rises on Positive Data From Oral GLP-1 Study

Dow Jones
03/16

By Nicholas G. Miller

 

The stock of Structure Therapeutics rose after the company reported positive topline data from a phase two study of its aleniglipron oral GLP-1 drug.

The stock rose 8% to $58.07 in premarket trading and has more than doubled over the past 12 months.

The company said the drug showed the highest efficacy among oral GLP-1 drugs and comparable efficacy to injectable GLP-1s.

The drug showed placebo-adjusted mean weight loss of 16.3% at 180 milligrams and 16.0% at 240 milligrams at 44 weeks with no evidence of weight loss plateau.

"The consistent weight loss observed across multiple studies to date reaffirms aleniglipron's potential to be a best-in-class oral GLP-1, with injectable-like efficacy that could become a backbone oral small molecule therapy for obesity," said Chief Executive Raymond Stevens.

 

Write to Nicholas G. Miller at nicholas.miller@wsj.com.

 

(END) Dow Jones Newswires

March 16, 2026 08:41 ET (12:41 GMT)

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