Apellis Pharmaceuticals (APLS) shares were 140% higher pre-bell Tuesday after the company agreed to be acquired by Biogen (BIIB) for about $5.60 billion in cash plus contingency payments.

Centessa Pharmaceuticals (CNTA) stock was up 48% after the company agreed to be bought by Eli Lilly (LLY) in a deal worth up to $7.80 billion.

Allbirds (BIRD) shares were 17% higher after the company said late Monday it has agreed to sell its intellectual property along with certain other assets and liabilities to American Exchange Group for about $39 million.

Artelo Biosciences (ARTL) stock was up 12%, a day after the company said it closed an $11 million private placement of common shares and warrants.