Abivax (ABVX) faces an increasing risk of a black box warning for obefazimod due to malignancies reported from a recent trial, Wedbush Securities said in a note.

Shares sank 42% following an increase in intraday trading volume to over 14 million from a daily average of about 1.1 million.

Fulcrum Therapeutics (FULC) shares slumped 52% amid heavy trading after multiple analysts downgraded the stock and sharply lowered their price targets.

Intraday trading volume soared to more than 23.3 million shares from a daily average of about 910,000.

Goldman Sachs downgraded Intuit (INTU) to sell from neutral while adjusting its price target to $276 from $519.

Shares dropped over 8%, with intraday trading volume rising to more than 5.1 million versus the stock's daily average of about 4.12 million.

Price: 74.19, Change: -55.50, Percent Change: -42.79