Expedia's integration into Meta's artificial-intelligence agent Muse was lauded by Wall Street. Investors felt differently.

Shares of Expedia fell 6.8% to $261.07 on Wednesday, pacing toward its lowest close since hitting $259.94 on July 24. It was among the worst performers in the S&P 500 for the session. Airbnb stock dropped 6%, Booking Holdings declined 4.6%, and Trivago fell 13%. The S&P 500 was down 0.6%.

Meta's Muse release disrupted stocks of online travel booking platforms earlier this week as concerns mounted over whether the AI assistant provided a better service. On Tuesday, Expedia announced in a social media post its trip-planning platform would be integrated into Muse, allowing users to book travel directly through the agent.

Expedia stock has dropped, but analysts applauded the partnership with Meta.

Morgan Stanley analysts wrote that it is an "important step" in optimizing the trip-planning experience as consumers shift toward reliance on travel agents. Use of agents for travel planning may become "increasingly necessary," benefiting Expedia, the analysts said.

B. Riley Securities analysts called Expedia's integration into Muse a "positive" for the travel company's brand awareness on Tuesday, adding Expedia's position in the market could be boosted as more competitors adopt AI assistants.

Even before the announcement, Muse users could already access Expedia's inventory, the analysts wrote. They expect a "deeper partnership to further expose Muse's growing user base to Expedia's inventory."

For now though, Meta's impact on the sector has been to send shares lower.

Shopify shares rose more than 7% on Monday and Tuesday after announcing a partnership with Muse, but the stock fell 3.6% on Wednesday.