生物技术企业Enveric Biosciences Inc.专注于神经塑性小分子疗法的开发,针对精神与神经系统疾病。最新宣布的临床前研究显示,其领先候选药物EB-003在创伤后应激障碍(PTSD)模型中表现卓越。实验结果揭示:给药一小时后,EB-003显著降低啮齿类动物模型中的冻结行为,标志着快速恐惧消退效应。这种神经塑性药物可能增强海马体神经可塑性,同时避免幻觉风险,为PTSD治疗带来新希望。相比之下,现有FDA批准疗法如选择性血清素再摄取抑制剂(SSRIs),仅20%至30%患者获得完全缓解,且需数周才见效。研究还将EB-003与MDMA对比,后者虽具临床益处却未获官方批准。
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