5月30日,宜明昂科-B盘中涨超18%,月内股价累涨超110%。
消息面上,5月22日,宜明昂科公布IMM2510中国I/II期单药治疗NSCLC等实体瘤的有效性(13例)及安全性数据(106例)。宜明昂科已于2024年12月开展针对一线驱动基因阴性NSCLC和TNBC的中国II期临床(IMM2510联合化疗),将于2025H2公布超过60例一线NSCLC患者经的初步安全性和有效性结果。
据悉,IMM2510/AXN-2510是一种PD-L1和VEGF的双特异性抗体,目前正开发用于治疗多种实体肿瘤癌症。开源证券指出,PD-(L)1/VEGF双抗作为有望迭代PD-(L)1单抗市场的下一代IO基石药物,后续与ADC/TCE等联用将持续拓宽市场空间。截至2025年5月,MNC中仅辉瑞和默沙东通过引进布局此赛道,后续随着数据的不断成熟及联合应用潜力的不断验证,中国其他早期PD-(L)1/VEGF双抗也将有机会BD出海。目前PD-(L)1/VEGF双抗赛道景气度不断提高,相关标的有望持续受益。
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