Geron Highlights New RYTELO Clinical Data in Myeloid Malignancies at ASH 2025
Reuters
Nov 03
Geron Highlights New RYTELO Clinical Data in Myeloid Malignancies at ASH 2025
Geron Corporation has announced that five presentations highlighting the clinical activity of RYTELO® (imetelstat) in myeloid hematologic malignancies have been accepted for the 67th American Society of Hematology $(ASH)$ 2025 Annual Meeting, scheduled for December 6-9, 2025, in Orlando, FL. The accepted abstracts include one oral and four poster presentations, featuring new clinical and translational analyses of imetelstat in lower-risk myelodysplastic syndromes/neoplasms (LR-MDS) and myelofibrosis (MF). Among the presentations, an oral session will discuss the correlation between treatment-emergent cytopenias and clinical response with imetelstat in patients with LR-MDS, based on data from the IMerge Trial. Additionally, interim results from an investigator-led study of imetelstat in high-risk MDS will be presented as a poster, indicating limited single-agent activity in this patient group. These results are scheduled to be presented at the ASH 2025 meeting and have not yet been presented.
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