Press Release: Predictive Oncology Reports Third Quarter 2025 Financial Results and Provides Update on Digital Asset Strategy

Dow Jones
Nov 15

PITTSBURGH, Nov. 14, 2025 (GLOBE NEWSWIRE) -- Predictive Oncology (Nasdaq: POAI), an AI-driven drug discovery company that has expanded its business to include a digital asset strategy focused on ATH, the native utility token of the Aethir network, today reported financial and operating results for the quarter ended September 30, 2025, and provided a corporate update.

Q3 2025 and Recent Highlights:

   -- Announced the initiation of a digital asset treasury strategy focused on 
      ATH, the native utility token of the Aethir ecosystem, supported by two 
      private placements pursuant to which the Company received aggregate cash 
      gross proceeds of approximately $50.8 million and in-kind contributions 
      of locked and unlocked ATH with an aggregate notional value of 
      approximately $292.7 million as of the signing of the private placements. 
 
          -- As of November 10, 2025, the Company held approximately 5.70 
             billion ATH, with a market value of approximately $152.8 million, 
             based on a price of $0.0268 per ATH, the price reported on the 
             Coinbase exchange as of 4:00 p.m. Eastern Time on such date, of 
             which 3.7 billion ATH are locked and subject to vesting and/or 
             transfer restrictions and 2.0 billion ATH are unlocked. 
 
          -- Enables Predictive Oncology, through the use of ATH on the Aethir 
             network, to function as an operator on the Aethir ecosystem with 
             the ability to potentially create utility for the digital assets 
             held by Predictive Oncology, allowing its Strategic Compute 
             Reserve to help stimulate and onboard supply while satisfying 
             enterprise demand for compute. 
 
          -- Appointed Shawn Matthews, CEO of DNA Holdings and Former CEO of 
             Cantor Fitzgerald, to its Board of Directors. 
 
   -- With its investment in Aethir's native token to create a Strategic 
      Compute Reserve, Predictive Oncology is expanding its business to include 
      active digital asset management -- developing systems to monetize AI 
      infrastructure through real enterprise deployments intended to generate 
      booked revenue and cash earnings while meeting global AI infrastructure 
      demand across industries through its expected use of ATH on the Aethir 
      network. 
 
   -- Announced a strategic collaboration with Every Cure to identify and 
      prioritize drugs for repurposing into new indications to improve patient 
      outcomes and save lives. 

"The clear highlight since our last quarterly update was our announcement in September that we have embarked on a digital asset treasury strategy focused on the Aethir ecosystem and its native utility token, ATH," stated Raymond Vennare, Chairman and Chief Executive Officer of Predictive Oncology. "We recognize a key inhibitor to AI innovation across sectors is the availability of high performance, affordable AI infrastructure. Aethir operates the world's largest decentralized GPU network, offering enterprise-grade AI at a significantly lower cost as compared to other providers. We view expanded access to affordable and reliable AI infrastructure as key to eliminating the 'bottleneck' that we believe is limiting breakthrough innovation. To that end, we are excited that Predictive Oncology is able deploy a new business line in active digital asset management, allowing us to play a role in the 'democratization' of AI broadly while also addressing the growing need for advanced computing power."

"Aethir is thrilled to partner with Predictive Oncology to drive the future of decentralized AI infrastructure," said Kyle Okamoto, a member of Predictive Oncology's advisory board and General Manager & CTO of Aethir. "By providing the infrastructure backbone for Predictive Oncology's new digital asset strategy, Aethir is unlocking greater value for its ecosystem, further democratizing AI access, and empowering enterprises with flexible, scalable, and cost-effective compute solutions. I am excited for what we'll achieve through this mutually beneficial synergy. Predictive Oncology's new digital asset strategy will be a use case of how the AI ecosystem actually grows: not through passive capital, but through operators who acquire compute infrastructure, deploy it to real enterprises, and monetize it transparently. That's a model aimed to scale--and it's exactly why Aethir and Predictive Oncology are so excited about this synergy."

Q3 2025 Financial Summary:

   -- Concluded the third quarter of 2025 with $181,667 in cash and cash 
      equivalents from continuing operations, compared to $611,822 as of 
      December 31, 2024, and a stockholders' deficit of $77.4 million as 
      compared to a stockholders' deficit of $202,610 as of December 31, 2024. 
      During the third quarter of 2025, the company recorded a derivative 
      liability of $74.4 million related to the initiation of its digital asset 
      treasury strategy focused on the ATH token. 
 
   -- Basic and diluted loss per common share from continuing operations for 
      the quarter ended September 30, 2025, was $(107.24), as compared to 
      $(4.99) for the quarter ended September 30, 2024. Basic and diluted loss 
      per common share from continuing operations for the quarter ended 
      September 30, 2025 included a loss on derivative instruments of $74.4 
      million related to the initiation of its digital asset treasury strategy 
      focused on the ATH token. 

Q3 2025 Financial Results:

   -- The Company recorded revenue of $3,618 and $3,907 in the three months 
      ended September 30, 2025 and 2024, respectively. Revenue in the three 
      months ended September 30, 2025 was largely unchanged from the comparable 
      period in 2024. 
 
   -- General and administrative expenses increased by $1.1 million to $2.6 
      million in the three months ended September 30, 2025, compared to $1.5 
      million in the comparable period in 2024. The increase was primarily due 
      to increased legal fees and increased stock-based compensation expense, 
      offset by decreased employee salaries and benefits resulting from lower 
      headcount. Stock-based compensation expense increased due to restricted 
      stock units granted during the three months ended September 30, 2025 to 
      employees, directors, and consultants. 
 
   -- Operations, research and development expense was $528,557 in the three 
      months ended September 30, 2025, largely unchanged from $535,236 in the 
      comparable period in 2024. 
 
   -- Sales and marketing expenses were $133,494 in the three months ended 
      September 30, 2025, compared to $72,667 in the comparable period in 2024. 
      The increase was primarily due to increased fees for digital marketing 
      consultants, partially offset by lower employee compensation resulting 
      from lower headcount. 
 
   -- Net cash used in operating activities of continuing operations was $5.9 
      million for the nine months ended September 30, 2025, compared to $8.0 
      million for the nine months ended September 30, 2024. Cash used in 
      operating activities of continuing operations decreased in the 2025 
      period primarily due to lower cash operating losses, partially offset by 
      increased cash used in working capital. Lower cash operating losses were 
      primarily due to decreased operating expenses. Cash used in working 
      capital increased due to increases in prepaid expenses and decreases in 
      operating lease liabilities, offset by increases in accounts payable and 
      accrued expenses. The increases in accounts payable and accrued expenses 
      were partially offset by the write-offs of aged accounts payable and 
      related accrued expenses. 

Conference Call & Webcast

Senior executives from Predictive Oncology and Aethir will host an investor conference call and webcast to review the Company's third quarter results and new digital asset treasury strategy in more detail on Monday, November 17(th) , at 9:00am EST.

To access the call, investors and analysts should dial (346) 248-7799 and reference Meeting ID 87812905132, Passcode 302383. The webcast of the call can be accessed here. A replay of the webcast will be made available under "Events & Presentations" on Predictive Oncology's Investors website.

About Predictive Oncology

Predictive Oncology is on the cutting edge of the rapidly growing use of artificial intelligence and machine learning to expedite early drug discovery and enable drug development for the benefit of cancer patients worldwide. The Company's scientifically validated AI platform, PEDAL, is able to predict with 92% accuracy if a tumor sample will respond to a certain drug compound, allowing for a more informed selection of drug/tumor type combinations for subsequent in-vitro testing. Together with the Company's vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry's broadest AI-based drug discovery solutions, further complimented by its wholly owned CLIA laboratory facility.

Predictive Oncology also operates a digital asset treasury focused on the Aethir $(ATH)$ token, creating the world's first Strategic Compute Reserve. Through its holdings of ATH, the Company functions as an operator on the Aethir ecosystem, strengthening Aethir's ability to provide the global infrastructure layer for the future of AI, democratizing access to AI infrastructure.

Predictive Oncology is headquartered in Pittsburgh, PA.

Forward-Looking Statements:

This press release contains "forward-looking statements" as defined by the Private Securities Litigation Reform Act of 1995, Section 27A of the Securities Act, and Section 21E of the Securities Exchange Act of 1934, as amended. This press release also includes express and implied forward-looking statements regarding the Company's current expectations, estimates, opinions and beliefs that are not historical facts. Such forward-looking statements may be identified by words such as "believes, " "expects," "endeavors," "anticipates," "intends," "plans," "estimates, " "projects," "should" and "objective" and the negative and variations of such words and similar words. These statements are made on the basis of current knowledge and, by their nature, involve numerous assumptions and uncertainties. The Company cannot guarantee the accuracy, completeness, or reliability of statements made by third parties in this press release, nor can it assure that any expectations, forecasts, or outcomes expressed by third parties will materialize. Nothing set forth herein should be regarded as a representation, warranty or prediction that we will achieve or are likely to achieve any particular future result. Actual results may differ materially from those indicated in the forward-looking statements because the realization of those results is subject to many risks and uncertainties, including, without limitation, the risk of failing to realize the anticipated benefits of the Company's proposed digital asset treasury strategy, economic conditions, fluctuations in the market price of ATH and other digital assets, the impact of the evolving regulatory environment on the Company's business, the ability of the Company to execute on its digital asset treasury strategy and implications for shareholders and for the Company's core business, the ability of the Aethir ecosystem to perform in a manner consistent with projections, receipt of shareholder approval for the exercise of the pre-funded warrants issued in connection with the private placement pursuant to which the Company issued pre-funded warrants in exchange for locked and unlocked ATH, the risks related to the success of our collaboration arrangements, commercialization activities and product sales levels by our collaboration partners, and the other risks, uncertainties, and other factors described under "Risk Factors," "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in the documents we file with the U.S. Securities and Exchange Commission. Forward-looking statements contained in this press release are made as of the date of this press release, and the Company undertakes no duty to update such information except as required under applicable law.

Investor Relations Contact:

Michael Moyer

LifeSci Advisors, LLC

mmoyer@lifesciadvisors.com

 
                      PREDICTIVE ONCOLOGY INC. 
                CONDENSED CONSOLIDATED BALANCE SHEETS 
                             (Unaudited) 
                                    September 30,     December 31, 
                                         2025             2024 
                                    --------------  ---------------- 
ASSETS 
Current assets: 
Cash and cash equivalents           $     181,667   $     611,822 
Accounts receivable                        26,009          34,154 
Inventories                                37,989          45,760 
Prepaid expense and other assets          843,938         272,779 
Current assets of discontinued 
 operations                                14,348       1,261,403 
                                     ------------    ------------ 
Total current assets                    1,103,951       2,225,918 
 
Property and equipment, net               253,187         347,588 
Intangibles, net                           47,522          50,955 
Lease right-of-use assets               1,634,160       2,047,241 
Other long-term assets                     98,478          98,478 
Non-current assets of discontinued 
 operations                                     -         202,337 
                                     ------------    ------------ 
Total assets                        $   3,137,298   $   4,972,517 
                                     ============    ============ 
 
  LIABILITIES AND STOCKHOLDERS' 
             DEFICIT 
Current liabilities: 
Accounts payable                    $   2,717,725   $   1,044,394 
Note payable                              187,374               - 
Accrued expenses and other 
 liabilities                            1,133,046       1,236,378 
Derivative liability                   74,366,000               - 
Contract liabilities                      146,576         224,076 
Lease liability                           627,909         555,169 
Current liabilities of 
 discontinued operations                  310,046         533,384 
                                     ------------    ------------ 
Total current liabilities              79,488,676       3,593,401 
 
Lease liability -- net of current 
 portion                                1,076,544       1,558,239 
Non-current liabilities of 
 discontinued operations                        -          23,487 
                                     ------------    ------------ 
Total liabilities                      80,565,220       5,175,127 
                                     ------------    ------------ 
Contingencies (see Note 7) 
 
Stockholders' deficit: 
Preferred stock, 20,000,000 
shares authorized inclusive of 
designated below 
Series B Convertible Preferred 
 Stock, $.01 par value, 2,300,000 
 shares authorized, 79,246 shares 
 outstanding as of September 30, 
 2025 and December 31, 2024                   792             792 
Common stock, $.01 par value, 
 200,000,000 shares authorized, 
 767,058 and 444,475 shares 
 outstanding as of September 30, 
 2025, and December 31, 2024, 
 respectively                               7,671           4,445 
Additional paid-in capital            185,155,064     180,218,424 
Accumulated deficit                  (262,591,449)   (180,426,271) 
                                     ------------    ------------ 
Total stockholders' deficit           (77,427,922)       (202,610) 
                                     ------------    ------------ 
 
Total liabilities and 
 stockholders' deficit              $   3,137,298   $   4,972,517 
                                     ============    ============ 
 
 
 
                             PREDICTIVE ONCOLOGY INC. 
                   CONDENSED CONSOLIDATED STATEMENTS OF NET LOSS 
                                    (Unaudited) 
                           Three Months Ended             Nine Months Ended 
                              September 30,                  September 30, 
                           2025           2024          2025           2024 
Revenue                $      3,618   $     3,907   $    116,610   $     76,020 
Cost of sales                 8,356        11,177         71,695         47,468 
                        -----------    ----------    -----------    ----------- 
Gross profit (loss)          (4,738)       (7,270)        44,915         28,552 
 
Operating expenses: 
     General and 
      administrative      2,613,075     1,545,271      6,316,930      5,696,109 
     Operations, 
      research and 
      development           528,557       535,236      1,548,678      1,724,013 
     Sales and 
      marketing             133,494        72,667        406,086        815,563 
Total operating 
 expenses                 3,275,126     2,153,174      8,271,694      8,235,685 
Total operating 
 (loss)                  (3,279,864)   (2,160,444)    (8,226,779)    (8,207,133) 
Other income                  2,631        36,379        688,483         64,497 
Other expense                (3,504)       (5,822)        (6,752)        (9,393) 
Gain (loss) on 
 derivative 
 instruments            (74,366,000)            7    (74,366,000)         1,375 
                        -----------    ----------    -----------    ----------- 
Loss from continuing 
 operations             (77,646,737)   (2,129,880)   (81,911,048)    (8,150,654) 
Loss from 
 discontinued 
 operations                  (5,106)     (964,810)      (254,130)    (2,344,140) 
                        -----------    ----------    -----------    ----------- 
Net (loss)             $(77,651,843)  $(3,094,690)  $(82,165,178)  $(10,494,794) 
                        ===========    ==========    ===========    =========== 
 
Loss per common 
share, basic and 
diluted: 
     Loss from 
      continuing 
      operations       $    (107.24)  $     (4.99)  $    (135.70)  $     (24.23) 
     Loss from 
      discontinued 
      operations              (0.01)        (2.27)         (0.42)         (6.97) 
                        -----------    ----------    -----------    ----------- 
Net (loss) per common 
 share, basic and 
 diluted               $    (107.25)  $     (7.26)  $    (136.12)  $     (31.20) 
                        ===========    ==========    ===========    =========== 
 
Weighted average 
 shares used in 
 computation -- basic 
 and diluted                723,998       426,423        603,605        336,423 
 

(END) Dow Jones Newswires

November 14, 2025 17:12 ET (22:12 GMT)

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