AnaptysBio (ANAB): Evaluating Valuation After Phase 2 Ulcerative Colitis Trial Discontinuation and Cost Savings

Simply Wall St.

Nov 20

AnaptysBio (ANAB) just shared results from its Phase 2 study of rosnilimab in moderate to severe ulcerative colitis. The drug was safe but failed to hit key efficacy goals, prompting the company to ...

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The drug was safe but failed to hit key efficacy goals, prompting the company to ...</p>\n\n<a href=\"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-anab/anaptysbio/news/anaptysbio-anab-evaluating-valuation-after-phase-2-ulcerativ\">Source Link</a>\n\n</div>\n","source":"simplywall_highlight","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>AnaptysBio (ANAB): Evaluating Valuation After Phase 2 Ulcerative Colitis Trial Discontinuation and Cost Savings</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nAnaptysBio (ANAB): Evaluating Valuation After Phase 2 Ulcerative Colitis Trial Discontinuation and Cost Savings\n</h2>\n\n<h4 class=\"meta\">\n\n\n2025-11-20 00:26 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-anab/anaptysbio/news/anaptysbio-anab-evaluating-valuation-after-phase-2-ulcerativ><strong>Simply Wall St.</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>AnaptysBio (ANAB) just shared results from its Phase 2 study of rosnilimab in moderate to severe ulcerative colitis. The drug was safe but failed to hit key efficacy goals, prompting the company to ...</p>\n\n<a href=\"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-anab/anaptysbio/news/anaptysbio-anab-evaluating-valuation-after-phase-2-ulcerativ\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"ANAB","symbol_name":"Anaptysbio Inc","start_time":0,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-anab/anaptysbio/news/anaptysbio-anab-evaluating-valuation-after-phase-2-ulcerativ","article_id":"2584312978","we_media_id":null,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-anab/anaptysbio/news/anaptysbio-anab-evaluating-valuation-after-phase-2-ulcerativ","rn_cache_url":null,"directOrigin":true},"url":"https://stock-news.laohu8.com/highlight/detail?id=2584312978","pubTimestamp":1763569592,"columns":[],"sourceInfo":{"source_id":"simplywall_highlight","name":"Simply Wall St."},"weMediaInfo":null,"summary":"AnaptysBio (ANAB) just shared results from its Phase 2 study of rosnilimab in moderate to severe ulcerative colitis. The drug was safe but failed to hit key efficacy goals, prompting the company to discontinue the trial.\nSee our latest analysis for AnaptysBio.\nOver the past year, AnaptysBio’s share price has soared, with a 177% year-to-date rally and an 84% total return for shareholders. Most of the upside has built in recent months as anticipation grew ahead of key trial readouts. While...","collect":0,"end_time":0,"defaultTopTitle":"simplywall.st","property":[],"viewcount":null,"language":"en","relate_stocks":{"ANAB":"Anaptysbio Inc","BK4139":"生物科技"},"translate_title":"AnaptysBio(ANAB)：评估2期溃疡性结肠炎试验终止后的估值和成本节约","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"ANAB":1.5},"content_text":"AnaptysBio (ANAB) just shared results from its Phase 2 study of rosnilimab in moderate to severe ulcerative colitis. The drug was safe but failed to hit key efficacy goals, prompting the company to discontinue the trial. See our latest analysis for AnaptysBio. Over the past year, AnaptysBio’s share price has soared, with a 177% year-to-date rally and an 84% total return for shareholders. Most of the upside has built in recent months as anticipation grew ahead of key trial readouts. While today’s news tempers some momentum, the stock remains firmly in positive territory, demonstrating resilient investor enthusiasm despite mixed clinical outcomes. If news-flow volatility like this has you thinking about what’s next, consider expanding your search and check out See the full list for free. The question now is whether AnaptysBio’s recent decline creates a genuine buying opportunity, or if the market has already factored in both the risks and all future growth potential at the current price. AdvertisementPrice-to-Sales of 6x: Is it justified? AnaptysBio currently trades at a price-to-sales ratio of 6x, substantially below sector peers and the US Biotechs industry average. With shares closing at $37.01, the market offers a notable discount on this key metric. The price-to-sales ratio reflects how much investors are willing to pay for every dollar of the company’s revenue. For a biotech name like AnaptysBio, which is not yet profitable and remains in the development phase, this metric is especially important because traditional earnings multiples are often not meaningful. Compared to the industry average price-to-sales ratio of 11.9x and a peer average of 10x, AnaptysBio appears attractively priced on this criterion. However, when measured against the estimated Fair Price-to-Sales Ratio of 2.3x, the stock looks expensive. This suggests the market may be pricing in continued revenue growth or future clinical successes despite recent setbacks. If the market’s expectations change, the multiple could move toward the fair ratio level. Explore the SWS fair ratio for AnaptysBio Result: Price-to-Sales of 6x (UNDERVALUED compared to industry/peers, OVERVALUED compared to fair ratio) However, clinical setbacks or unexpected negative trial results could quickly reshape sentiment and put further pressure on AnaptysBio’s valuation in the near term. Find out about the key risks to this AnaptysBio narrative.  Build Your Own AnaptysBio Narrative If you see things differently or want to dig into the numbers on your own terms, it only takes a few minutes to craft your own perspective. Do it your way A great starting point for your AnaptysBio research is our analysis highlighting 1 key reward and 4 important warning signs that could impact your investment decision. Looking for More Smart Investment Ideas? Smart investors never limit themselves to one opportunity. If you’re ready to make your next move or broaden your portfolio, take a look at these hand-picked routes to potential growth. Don’t let fresh market trends pass you by. Act now, so tomorrow’s winners are in your sights today.  Seize the chance for big returns by checking out these 3588 penny stocks with strong financials packed with companies that could be tomorrow’s breakout winners. Capitalize on transformative healthcare innovation by examining these 31 healthcare AI stocks that are changing the way medicine and technology intersect. Boost your income stream with these 18 dividend stocks with yields > 3% offering high yields and the financial stability many investors seek.   This article by Simply Wall St is general in nature. We provide commentary based on historical data\n    and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your\n    financial situation. We aim to bring you long-term focused analysis driven by fundamental data.\n    Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material.\n    Simply Wall St has no position in any stocks mentioned.New: Manage All Your Stock Portfolios in One PlaceWe've created the ultimate portfolio companion for stock investors, and it's free.• Connect an unlimited number of Portfolios and see your total in one currency• Be alerted to new Warning Signs or Risks via email or mobile• Track the Fair Value of your stocksTry a Demo Portfolio for FreeHave feedback on this article? Concerned about the content? Get in touch with us directly. 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