D. Western Therapeutics Institute (TYO:4576) said the observation period has finished in one of two global Phase III trials of K-321, its investigational treatment for Fuchs endothelial corneal dystrophy, according to a Friday filing on the Tokyo Stock Exchange.
The study, led by licensee Kowa, is testing the efficacy and safety of K-321 versus placebo when used as an eye drop after simultaneous Descemet's membrane stripping and cataract surgery.
Fuchs endothelial corneal dystrophy progressively damages the corneal endothelium, and corneal transplantation remains the main treatment for severe cases. Western Therapeutics and Kowa said they aim to develop K-321 as a new therapeutic option.