美股详情

本页面由Tiger Trade Technology Pte. Ltd.提供服务

Aprea Therapeutics, Inc.

0.8750

+0.07519.39%

盘后：0.8580-0.0170-1.94%17:20 EST

成交量：18.85万

成交额：15.58万

市值：611.96万

市盈率：-0.41

高：0.8800

开：0.7800

低：0.7595

收：0.7999

52周最高：2.79

52周最低：0.5480

股本：699.38万

流通股本：456.18万

量比：0.17

换手率：4.13%

股息：- -

股息率：- -

每股收益(TTM):-2.1364

每股收益(LYR):-2.3519

净资产收益率：-74.72%

总资产收益率：-41.90%

市净率：0.56

市盈率(LYR):-0.37

数据加载中...

总览公司新闻资讯公告

Aprea Therapeutics公司：220毫克剂量水平观察到肿瘤缩小50%及CA-125生物标志物显著降低

Aprea Therapeutics宣布Wee1抑制剂Apr-1051取得新进展，ACESOT-1051试验中观察到第二例部分缓解

Aprea Therapeutics强化DDR抗癌疗法全球专利布局，为管线拓展铺平道路

Aprea Therapeutics 宣布在评估Wee1抑制剂APR-1051的ACESOT-1051剂量递增试验中取得早期临床概念验证，首次扫描即观察到部分缓解

Aprea Therapeutics公司：2026年上半年将发布更多进展，年内完成剂量递增研究

Aprea Therapeutics, Inc. - 提交股东5.5百万股的再销售招股说明书 - SEC备案

Aprea Therapeutics首席执行官致股东信，强调2025年管线进展及2026年展望

Aprea Therapeutics, Inc.2025财年第三财季实现净利润-2.97百万美元，同比增加21.43%

Aprea Therapeutics公布Acesot-1051试验临床进展，显示出Wee1激酶抑制剂Apr-1051的早期活性信号

Aprea Therapeutics 建立 Atrn-119 的推荐二期剂量 (Rp2d)，考虑联合疗法

Aprea Therapeutics宣布将在EORTC-NCI-AACR分子靶点与癌症治疗国际会议上发表演讲

{"basename":"/hans","ssrTDKData":{"titleTemplate":"%s - 老虎证券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎证券,老虎证券开户,老虎券商,老虎证券官网,老虎证券app,tigertrade老虎证券,股票,炒股,新加坡股票交易平台,投资,投资理财","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www.itiger.com/hans/stock/APRE/news"},"companyName":"老虎证券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"APRE","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"APRE\",,,,,undefined,":{"symbol":"APRE","market":"US","secType":"STK","nameCN":"Aprea Therapeutics, Inc.","latestPrice":0.875,"timestamp":1772053200000,"preClose":0.7999,"halted":0,"volume":188546,"hourTrading":{"tag":"盘后","latestPrice":0.858,"preClose":0.875,"latestTime":"17:20 EST","volume":2485,"amount":2153.899097,"timestamp":1772058002770,"change":-0.017,"changeRate":-0.019429,"amplitude":0.019429},"delay":0,"changeRate":0.09388673584198017,"floatShares":4561818,"shares":6993838,"eps":-2.136425,"marketStatus":"盘后交易","change":0.0751,"latestTime":"02-25 18:17:02 EST","open":0.78,"high":0.88,"low":0.7595,"amount":155790.46905800002,"amplitude":0.150644,"askPrice":0.9,"askSize":50,"bidPrice":0.7774,"bidSize":100,"shortable":3,"etf":0,"ttmEps":-2.136425,"tradingStatus":3,"nextMarketStatus":{"tag":"收盘","tradingStatus":0,"beginTime":1772067600000},"marketStatusCode":4,"adr":0,"listingDate":1570075200000,"exchange":"NASDAQ","adjPreClose":0.7999,"preHourTrading":{"tag":"盘前","latestPrice":0.8,"preClose":0.7999,"latestTime":"08:59 EST","volume":3162,"amount":2526.40998468,"timestamp":1772027940037,"change":0.0001,"changeRate":0.000125,"amplitude":0.03988},"postHourTrading":{"tag":"盘后","latestPrice":0.858,"preClose":0.875,"latestTime":"17:20 EST","volume":2485,"amount":2153.899097,"timestamp":1772058002770,"change":-0.017,"changeRate":-0.019429,"amplitude":0.019429},"volumeRatio":0.169448,"impliedVol":4.309,"impliedVolPercentile":0},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"APRE\",,,,,undefined,":{"symbol":"APRE","floatShares":4561818,"roa":"-41.90%","roe":"-74.72%","lyrEps":-2.351886,"volumeRatio":0.169448,"shares":6993838,"dividePrice":0,"high":0.88,"amplitude":0.150644,"preClose":0.7999,"low":0.7595,"week52Low":0.548,"pbRate":"0.56","psRate":"12.53","week52High":2.79,"institutionHeld":0,"latestPrice":0.875,"committee":0.333333,"eps":-2.136425,"divideRate":0,"volume":188546,"delay":0,"ttmEps":-2.136425,"open":0.78,"prevYearClose":0.853,"prevWeekClose":0.7578,"prevMonthClose":0.796,"prevQuarterClose":0.853,"fiveDayClose":0.728,"twentyDayClose":0.829,"sixtyDayClose":1.25},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/APRE\",params:#limit:5,,,undefined,":[{"market":"US","date":"2025-11-12","symbol":"APRE","fiscalQuarterEnding":"2025/09","expectedEps":-0.11,"name":null,"time":"盘前","type":"earning","dateTimestamp":1762923600000,"reportTimeType":"pre","actualEps":-0.47},{"market":"US","date":"2025-08-12","symbol":"APRE","fiscalQuarterEnding":"2025/06","expectedEps":-0.77,"name":null,"time":"盘前","type":"earning","dateTimestamp":1754971200000,"reportTimeType":"pre","actualEps":-0.53},{"market":"US","date":"2025-05-14","symbol":"APRE","fiscalQuarterEnding":"2025/03","expectedEps":null,"name":null,"time":"盘前","type":"earning","dateTimestamp":1747195200000,"reportTimeType":"pre","actualEps":-0.66},{"market":"US","date":"2025-03-25","symbol":"APRE","fiscalQuarterEnding":"2024/12","expectedEps":-0.68,"name":null,"time":"盘前","type":"earning","dateTimestamp":1742875200000,"reportTimeType":"pre","actualEps":-0.49},{"market":"US","date":"2024-11-07","symbol":"APRE","fiscalQuarterEnding":"2024/09","expectedEps":-0.75,"name":null,"time":"盘前","type":"earning","dateTimestamp":1730955600000,"reportTimeType":"pre","actualEps":-0.64}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"APRE\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"APRE\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.3333,"buy":0.6667,"hold":0,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.6667,"analysts":3,"updateTime":1766379600000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/APRE\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"APRE","date":"2026-02-24","current":-0.363224,"percent":0.779579,"low":-2.650476,"twenty":-1.759797,"median":-1.002178,"eighty":-0.403773,"high":-0.098695,"avg":-1.081348,"sd":0.670947,"marketCap":5699977},"quantilePoints":[{"date":"2021-02-26","current":-2.484821,"twenty":-34.46748,"median":-20.252628,"eighty":-11.184636,"marketCap":127120962},{"date":"2021-03-05","current":-2.257046,"twenty":-34.037749,"median":-19.248981,"eighty":-10.941737,"marketCap":115468207},{"date":"2021-03-12","current":-2.447549,"twenty":-33.925511,"median":-19.038338,"eighty":-10.631393,"marketCap":125214147},{"date":"2021-03-19","current":-2.2978,"twenty":-33.780357,"median":-18.821501,"eighty":-10.452813,"marketCap":122883596},{"date":"2021-03-26","current":-2.064058,"twenty":-32.755739,"median":-18.607761,"eighty":-10.287158,"marketCap":110383368},{"date":"2021-04-01","current":-2.020479,"twenty":-32.591422,"median":-18.378532,"eighty":-10.229626,"marketCap":108052817},{"date":"2021-04-09","current":-2.178948,"twenty":-32.262121,"median":-18.226746,"eighty":-10.16585,"marketCap":116527548},{"date":"2021-04-16","current":-1.711465,"twenty":-32.177823,"median":-17.910783,"eighty":-9.345427,"marketCap":91527092},{"date":"2021-04-23","current":-1.798622,"twenty":-32.064592,"median":-17.762094,"eighty":-8.695216,"marketCap":96188194},{"date":"2021-04-30","current":-1.881819,"twenty":-31.894769,"median":-17.588624,"eighty":-8.461643,"marketCap":100637428},{"date":"2021-05-07","current":-1.687694,"twenty":-31.62866,"median":-17.316028,"eighty":-3.038108,"marketCap":90255883},{"date":"2021-05-14","current":-1.596483,"twenty":-31.35293,"median":-16.978382,"eighty":-2.868311,"marketCap":85806649},{"date":"2021-05-21","current":-1.702915,"twenty":-31.288391,"median":-16.826595,"eighty":-2.739929,"marketCap":91527092},{"date":"2021-05-28","current":-1.635902,"twenty":-31.275872,"median":-16.711981,"eighty":-2.593325,"marketCap":87925332},{"date":"2021-06-04","current":-1.892128,"twenty":-31.265856,"median":-16.547804,"eighty":-2.484821,"marketCap":101696769},{"date":"2021-06-11","current":-1.994618,"twenty":-31.260848,"median":-16.343357,"eighty":-2.434269,"marketCap":107205344},{"date":"2021-06-18","current":-1.986734,"twenty":-31.189488,"median":-16.021198,"eighty":-2.363065,"marketCap":106781608},{"date":"2021-06-25","current":-1.951257,"twenty":-31.115623,"median":-15.779579,"eighty":-2.320823,"marketCap":104874793},{"date":"2021-07-02","current":-2.136527,"twenty":-31.06805,"median":-13.830773,"eighty":-2.257728,"marketCap":114832602},{"date":"2021-07-09","current":-2.041921,"twenty":-31.048019,"median":-13.7274,"eighty":-2.232612,"marketCap":109747763},{"date":"2021-07-16","current":-2.006444,"twenty":-31.013875,"median":-13.621678,"eighty":-2.207766,"marketCap":107840949},{"date":"2021-07-23","current":-1.714741,"twenty":-30.946725,"median":-13.459571,"eighty":-2.162623,"marketCap":92162697},{"date":"2021-07-30","current":-1.710799,"twenty":-30.82267,"median":-13.302163,"eighty":-2.134294,"marketCap":91950829},{"date":"2021-08-06","current":-1.695031,"twenty":-30.51219,"median":-13.172947,"eighty":-2.115411,"marketCap":91103356},{"date":"2021-08-13","current":-1.592541,"twenty":-30.256795,"median":-12.977949,"eighty":-2.090091,"marketCap":85594781},{"date":"2021-08-20","current":-1.525724,"twenty":-30.164152,"median":-12.855839,"eighty":-2.050776,"marketCap":72670816},{"date":"2021-08-27","current":-1.863785,"twenty":-30.058989,"median":-12.733614,"eighty":-2.020479,"marketCap":88772805},{"date":"2021-09-03","current":-2.126227,"twenty":-29.64585,"median":-12.697434,"eighty":-2.020479,"marketCap":101273033},{"date":"2021-09-10","current":-2.063953,"twenty":-29.256294,"median":-12.688976,"eighty":-2.019249,"marketCap":98306877},{"date":"2021-09-17","current":-2.152916,"twenty":-28.919827,"median":-12.602049,"eighty":-2.013577,"marketCap":102544242},{"date":"2021-09-24","current":-2.015023,"twenty":-28.22266,"median":-12.540966,"eighty":-2.013577,"marketCap":95976326},{"date":"2021-10-01","current":-2.273017,"twenty":-27.855399,"median":-12.493978,"eighty":-2.014884,"marketCap":108264685},{"date":"2021-10-08","current":-2.295258,"twenty":-27.427728,"median":-12.421147,"eighty":-2.018581,"marketCap":109324027},{"date":"2021-10-15","current":-2.379773,"twenty":-27.299651,"median":-12.268438,"eighty":-2.020277,"marketCap":113349524},{"date":"2021-10-22","current":-2.273017,"twenty":-26.958112,"median":-12.235547,"eighty":-2.020479,"marketCap":108264685},{"date":"2021-10-29","current":-2.224087,"twenty":-26.874862,"median":-12.216752,"eighty":-2.025018,"marketCap":105934135},{"date":"2021-11-05","current":-2.277465,"twenty":-26.840708,"median":-12.118078,"eighty":-2.0386,"marketCap":108476554},{"date":"2021-11-12","current":-2.354398,"twenty":-26.799583,"median":-12.061693,"eighty":-2.041879,"marketCap":105393837},{"date":"2021-11-19","current":-2.100257,"twenty":-26.428281,"median":-11.789165,"eighty":-2.041879,"marketCap":94017313},{"date":"2021-11-26","current":-1.98997,"twenty":-26.301298,"median":-11.755274,"eighty":-2.023883,"marketCap":89080331},{"date":"2021-12-03","current":-1.870092,"twenty":-26.268341,"median":-11.554417,"eighty":-2.014745,"marketCap":83714046},{"date":"2021-12-10","current":-2.01874,"twenty":-26.154405,"median":-11.428106,"eighty":-2.005719,"marketCap":90368239},{"date":"2021-12-17","current":-1.563205,"twenty":-26.077869,"median":-11.310076,"eighty":-1.99782,"marketCap":69976356},{"date":"2021-12-23","current":-1.582386,"twenty":-25.959403,"median":-11.295797,"eighty":-1.98997,"marketCap":70834962},{"date":"2021-12-31","current":-1.409762,"twenty":-25.778612,"median":-11.025619,"eighty":-1.982004,"marketCap":63107511},{"date":"2022-01-07","current":-1.328245,"twenty":-25.728204,"median":-10.938692,"eighty":-1.971755,"marketCap":59458437},{"date":"2022-01-14","current":-1.232343,"twenty":-25.657667,"median":-10.667842,"eighty":-1.967187,"marketCap":55165409},{"date":"2022-01-21","current":-1.146031,"twenty":-25.618646,"median":-10.623876,"eighty":-1.952445,"marketCap":51301684},{"date":"2022-01-28","current":-0.915866,"twenty":-25.53011,"median":-10.452813,"eighty":-1.930585,"marketCap":40998417},{"date":"2022-02-04","current":-0.973407,"twenty":-25.512101,"median":-10.352225,"eighty":-1.921856,"marketCap":43574234},{"date":"2022-02-11","current":-0.959022,"twenty":-25.5091,"median":-10.285565,"eighty":-1.911837,"marketCap":42930280},{"date":"2022-02-18","current":-0.853529,"twenty":-25.495593,"median":-10.223247,"eighty":-1.902092,"marketCap":38207949},{"date":"2022-02-25","current":-0.800783,"twenty":-25.48959,"median":-10.178489,"eighty":-1.892128,"marketCap":35846783},{"date":"2022-03-04","current":-0.800783,"twenty":-25.476686,"median":-10.138069,"eighty":-1.864534,"marketCap":35846783},{"date":"2022-03-11","current":-0.87271,"twenty":-25.452072,"median":-9.687188,"eighty":-1.842201,"marketCap":39066554},{"date":"2022-03-18","current":-1.077192,"twenty":-25.422058,"median":-8.858386,"eighty":-1.831731,"marketCap":39993229},{"date":"2022-03-25","current":-1.083111,"twenty":-25.36203,"median":-8.692732,"eighty":-1.805958,"marketCap":40212972},{"date":"2022-04-01","current":-1.100866,"twenty":-25.351709,"median":-8.618187,"eighty":-1.785695,"marketCap":40872201},{"date":"2022-04-08","current":-1.071273,"twenty":-25.339519,"median":-8.367635,"eighty":-1.769395,"marketCap":39773486},{"date":"2022-04-14","current":-1.00025,"twenty":-25.327513,"median":-3.20956,"eighty":-1.75742,"marketCap":37136570},{"date":"2022-04-22","current":-0.881877,"twenty":-25.258481,"median":-2.96522,"eighty":-1.722624,"marketCap":32741709},{"date":"2022-04-29","current":-0.899633,"twenty":-25.223964,"median":-2.865826,"eighty":-1.711332,"marketCap":33400939},{"date":"2022-05-06","current":-0.834528,"twenty":-25.183445,"median":-2.75401,"eighty":-1.698185,"marketCap":30983765},{"date":"2022-05-13","current":-0.639213,"twenty":-25.168438,"median":-2.683607,"eighty":-1.68557,"marketCap":23732246},{"date":"2022-05-20","current":-0.28455,"twenty":-25.747713,"median":-10.946306,"eighty":-1.973348,"marketCap":15217417},{"date":"2022-05-27","current":-0.354069,"twenty":-25.663672,"median":-10.693013,"eighty":-1.968977,"marketCap":18935177},{"date":"2022-06-03","current":-0.359034,"twenty":-25.639654,"median":-10.628574,"eighty":-1.957196,"marketCap":19200731},{"date":"2022-06-10","current":-0.38496,"twenty":-25.534612,"median":-10.47352,"eighty":-1.935489,"marketCap":20587213},{"date":"2022-06-17","current":-0.350004,"twenty":-25.512101,"median":-10.390693,"eighty":-1.922838,"marketCap":18717776},{"date":"2022-06-24","current":-0.350179,"twenty":-25.512101,"median":-10.287158,"eighty":-1.914991,"marketCap":18727134},{"date":"2022-07-01","current":-0.339066,"twenty":-25.500095,"median":-10.240927,"eighty":-1.907403,"marketCap":18132845},{"date":"2022-07-08","current":-0.415586,"twenty":-25.492592,"median":-10.196048,"eighty":-1.899073,"marketCap":22225019},{"date":"2022-07-15","current":-0.490005,"twenty":-25.481848,"median":-10.172795,"eighty":-1.877128,"marketCap":26204886},{"date":"2022-07-22","current":-0.49438,"twenty":-25.461918,"median":-10.030394,"eighty":-1.858048,"marketCap":26438858},{"date":"2022-07-29","current":-0.420004,"twenty":-25.434064,"median":-8.986769,"eighty":-1.832492,"marketCap":22461331},{"date":"2022-08-05","current":-0.433129,"twenty":-25.386041,"median":-8.696873,"eighty":-1.811734,"marketCap":23163247},{"date":"2022-08-12","current":-0.415711,"twenty":-25.355837,"median":-8.659601,"eighty":-1.793579,"marketCap":22231748},{"date":"2022-08-19","current":-0.372434,"twenty":-25.344395,"median":-8.456674,"eighty":-1.774836,"marketCap":19917306},{"date":"2022-08-26","current":-0.34469,"twenty":-25.330515,"median":-3.375215,"eighty":-1.761382,"marketCap":18433629},{"date":"2022-09-02","current":-0.341277,"twenty":-25.274989,"median":-2.990068,"eighty":-1.72306,"marketCap":18251095},{"date":"2022-09-09","current":-0.317253,"twenty":-25.232969,"median":-2.907241,"eighty":-1.7166,"marketCap":16966334},{"date":"2022-09-16","current":-0.371952,"twenty":-25.201454,"median":-2.836837,"eighty":-1.703165,"marketCap":19891564},{"date":"2022-09-23","current":-0.31069,"twenty":-25.171439,"median":-2.731232,"eighty":-1.687366,"marketCap":16615306},{"date":"2022-09-30","current":-0.284434,"twenty":-25.154221,"median":-2.642193,"eighty":-1.672956,"marketCap":15211196},{"date":"2022-10-07","current":-0.297606,"twenty":-25.132856,"median":-2.497245,"eighty":-1.665072,"marketCap":15915591},{"date":"2022-10-14","current":-0.332569,"twenty":-25.054383,"median":-2.484821,"eighty":-1.648444,"marketCap":17785398},{"date":"2022-10-21","current":-0.299181,"twenty":-24.929824,"median":-2.449247,"eighty":-1.630986,"marketCap":15999838},{"date":"2022-10-28","current":-0.301675,"twenty":-24.863793,"median":-2.43646,"eighty":-1.616047,"marketCap":16133228},{"date":"2022-11-04","current":-0.287585,"twenty":-24.776752,"median":-2.414274,"eighty":-1.602686,"marketCap":15379689},{"date":"2022-11-11","current":-0.452691,"twenty":-24.736233,"median":-2.379773,"eighty":-1.592202,"marketCap":24209395},{"date":"2022-11-18","current":-0.376582,"twenty":-24.670403,"median":-2.36265,"eighty":-1.54882,"marketCap":20139164},{"date":"2022-11-25","current":-0.381537,"twenty":-24.607618,"median":-2.356796,"eighty":-1.427079,"marketCap":20404153},{"date":"2022-12-02","current":-0.475584,"twenty":-24.574511,"median":-2.353084,"eighty":-1.38467,"marketCap":25433644},{"date":"2022-12-09","current":-0.515323,"twenty":-24.494579,"median":-2.348636,"eighty":-0.521223,"marketCap":27558856},{"date":"2022-12-16","current":-0.317122,"twenty":-24.407519,"median":-2.335732,"eighty":-0.495255,"marketCap":16959296},{"date":"2022-12-23","current":-0.367564,"twenty":-24.382065,"median":-2.30485,"eighty":-0.486505,"marketCap":19656884},{"date":"2022-12-30","current":-0.328023,"twenty":-24.364056,"median":-2.296529,"eighty":-0.473106,"marketCap":17542271},{"date":"2023-01-06","current":-0.451601,"twenty":-22.941566,"median":-2.112098,"eighty":-0.628559,"marketCap":24151097},{"date":"2023-01-13","current":-0.483214,"twenty":-22.807202,"median":-2.099965,"eighty":-0.522169,"marketCap":25841727},{"date":"2023-01-20","current":-0.485395,"twenty":-22.657667,"median":-2.09425,"eighty":-0.516314,"marketCap":25958322},{"date":"2023-01-27","current":-0.469639,"twenty":-22.539955,"median":-2.086193,"eighty":-0.500087,"marketCap":25115710},{"date":"2023-02-03","current":-0.519287,"twenty":-22.341704,"median":-2.073153,"eighty":-0.495879,"marketCap":27770847},{"date":"2023-02-10","current":-0.469737,"twenty":-22.191776,"median":-2.064058,"eighty":-0.495879,"marketCap":25120957},{"date":"2023-02-17","current":-0.342888,"twenty":-21.61189,"median":-2.063953,"eighty":-0.49438,"marketCap":18337238},{"date":"2023-02-24","current":-0.35284,"twenty":-21.373988,"median":-2.048488,"eighty":-0.490005,"marketCap":18869439},{"date":"2023-03-03","current":-0.363217,"twenty":-21.138565,"median":-2.037921,"eighty":-0.483214,"marketCap":19424422},{"date":"2023-03-10","current":-0.348688,"twenty":-21.064221,"median":-2.023316,"eighty":-0.474692,"marketCap":18647445},{"date":"2023-03-17","current":-0.357682,"twenty":-20.345559,"median":-2.019471,"eighty":-0.470331,"marketCap":19128431},{"date":"2023-03-24","current":-0.318247,"twenty":-20.252628,"median":-2.014676,"eighty":-0.46389,"marketCap":17019494},{"date":"2023-03-31","current":-0.145812,"twenty":-19.862321,"median":-2.006444,"eighty":-0.451998,"marketCap":16427511},{"date":"2023-04-06","current":-0.127188,"twenty":-19.445993,"median":-2.001678,"eighty":-0.445953,"marketCap":14329228},{"date":"2023-04-14","current":-0.139112,"twenty":-19.193222,"median":-1.995664,"eighty":-0.433024,"marketCap":15672594},{"date":"2023-04-21","current":-0.130169,"twenty":-19.101531,"median":-1.98997,"eighty":-0.415695,"marketCap":14665070},{"date":"2023-04-28","current":-0.131494,"twenty":-19.048251,"median":-1.986734,"eighty":-0.415066,"marketCap":14814332},{"date":"2023-05-05","current":-0.127188,"twenty":-19.003644,"median":-1.975584,"eighty":-0.406795,"marketCap":14329228},{"date":"2023-05-12","current":-0.129341,"twenty":-18.890889,"median":-1.972938,"eighty":-0.403729,"marketCap":14571780},{"date":"2023-05-19","current":-0.127839,"twenty":-18.752113,"median":-1.970966,"eighty":-0.398061,"marketCap":13947862},{"date":"2023-05-26","current":-0.122739,"twenty":-18.63564,"median":-1.967485,"eighty":-0.390079,"marketCap":13391485},{"date":"2023-06-02","current":-0.125178,"twenty":-18.613337,"median":-1.961595,"eighty":-0.386447,"marketCap":13657549},{"date":"2023-06-09","current":-0.119021,"twenty":-18.560057,"median":-1.937224,"eighty":-0.382222,"marketCap":12985867},{"date":"2023-06-16","current":-0.116627,"twenty":-18.406412,"median":-1.935489,"eighty":-0.376582,"marketCap":12724657},{"date":"2023-06-23","current":-0.109103,"twenty":-18.361805,"median":-1.927633,"eighty":-0.37416,"marketCap":11903711},{"date":"2023-06-30","current":-0.101921,"twenty":-18.346936,"median":-1.922838,"eighty":-0.371822,"marketCap":11120081},{"date":"2023-07-07","current":-0.099527,"twenty":-18.297373,"median":-1.917474,"eighty":-0.367136,"marketCap":10858871},{"date":"2023-07-14","current":-0.113549,"twenty":-18.137533,"median":-1.911837,"eighty":-0.363557,"marketCap":12388815},{"date":"2023-07-19","current":-0.119706,"twenty":-18.003713,"median":-1.909551,"eighty":-0.363129,"marketCap":13060498},{"date":"2023-07-27","current":-0.102605,"twenty":-17.973975,"median":-1.903953,"eighty":-0.361004,"marketCap":11194713},{"date":"2023-08-04","current":-0.13065,"twenty":-17.899631,"median":-1.900011,"eighty":-0.358793,"marketCap":14254601},{"date":"2023-08-11","current":-1.052846,"twenty":-17.814136,"median":-1.890157,"eighty":-0.357129,"marketCap":14851279},{"date":"2023-08-18","current":-0.953649,"twenty":-17.772007,"median":-1.870092,"eighty":-0.358097,"marketCap":13452022},{"date":"2023-08-25","current":-0.966894,"twenty":-17.739791,"median":-1.860917,"eighty":-0.358408,"marketCap":13638856},{"date":"2023-09-01","current":-0.980139,"twenty":-17.650578,"median":-1.842201,"eighty":-0.358793,"marketCap":13825690},{"date":"2023-09-08","current":-1.027821,"twenty":-17.591102,"median":-1.832999,"eighty":-0.359324,"marketCap":14498291},{"date":"2023-09-15","current":-1.05961,"twenty":-17.474629,"median":-1.829043,"eighty":-0.360035,"marketCap":14946692},{"date":"2023-09-22","current":-1.141756,"twenty":-17.320985,"median":-1.81153,"eighty":-0.360588,"marketCap":16105434},{"date":"2023-09-29","current":-1.077173,"twenty":-17.29992,"median":-1.798622,"eighty":-0.361239,"marketCap":15194433},{"date":"2023-10-06","current":-1.290075,"twenty":-17.187165,"median":-1.789637,"eighty":-0.361926,"marketCap":18197597},{"date":"2023-10-13","current":-1.393387,"twenty":-16.99387,"median":-1.778398,"eighty":-0.363129,"marketCap":19654899},{"date":"2023-10-20","current":-1.324512,"twenty":-16.962893,"median":-1.769395,"eighty":-0.363129,"marketCap":18683365},{"date":"2023-10-27","current":-1.021199,"twenty":-16.920765,"median":-1.766929,"eighty":-0.363164,"marketCap":14404874},{"date":"2023-11-03","current":-0.943053,"twenty":-16.845181,"median":-1.755043,"eighty":-0.36328,"marketCap":13302555},{"date":"2023-11-10","current":-1.072855,"twenty":-16.814204,"median":-1.72335,"eighty":-0.363557,"marketCap":15133525},{"date":"2023-11-17","current":-1.054712,"twenty":-16.770837,"median":-1.721006,"eighty":-0.364406,"marketCap":14012523},{"date":"2023-11-24","current":-1.091275,"twenty":-16.724991,"median":-1.713103,"eighty":-0.365403,"marketCap":14498291},{"date":"2023-12-01","current":-1.023773,"twenty":-16.680384,"median":-1.703541,"eighty":-0.366157,"marketCap":13601489},{"date":"2023-12-07","current":-1.023773,"twenty":-16.650647,"median":-1.700944,"eighty":-0.36684,"marketCap":13601489},{"date":"2023-12-14","current":-1.102525,"twenty":-16.529217,"median":-1.691362,"eighty":-0.36717,"marketCap":14647758},{"date":"2023-12-22","current":-1.068774,"twenty":-16.443721,"median":-1.687147,"eighty":-0.367434,"marketCap":14199357},{"date":"2023-12-29","current":-1.051899,"twenty":-16.417701,"median":-1.677292,"eighty":-0.368377,"marketCap":13975157},{"date":"2024-01-05","current":-1.417532,"twenty":-16.361943,"median":-1.671379,"eighty":-0.370814,"marketCap":18832831},{"date":"2024-01-12","current":-1.611599,"twenty":-16.244231,"median":-1.671379,"eighty":-0.371887,"marketCap":21411136},{"date":"2024-01-19","current":-1.454124,"twenty":-16.15254,"median":-1.669408,"eighty":-0.371995,"marketCap":19318973},{"date":"2024-01-26","current":-1.54691,"twenty":-16.003851,"median":-1.663496,"eighty":-0.37227,"marketCap":20551701},{"date":"2024-02-02","current":-1.603162,"twenty":-15.915877,"median":-1.650593,"eighty":-0.373728,"marketCap":21299036},{"date":"2024-02-09","current":-1.935016,"twenty":-15.829142,"median":-1.655612,"eighty":-0.375633,"marketCap":25707936},{"date":"2024-02-16","current":-1.60288,"twenty":-14.645536,"median":-1.662861,"eighty":-0.37648,"marketCap":21295299},{"date":"2024-02-23","current":-1.792616,"twenty":-13.874471,"median":-1.665466,"eighty":-0.376582,"marketCap":23816059},{"date":"2024-03-01","current":-2.379429,"twenty":-13.835001,"median":-1.671379,"eighty":-0.376656,"marketCap":31612253},{"date":"2024-03-08","current":-2.09536,"twenty":-13.785194,"median":-1.675804,"eighty":-0.377116,"marketCap":27838213},{"date":"2024-03-15","current":-1.493472,"twenty":-13.731629,"median":-1.676288,"eighty":-0.379199,"marketCap":19841733},{"date":"2024-03-22","current":-1.785978,"twenty":-13.702497,"median":-1.683205,"eighty":-0.382906,"marketCap":23727873},{"date":"2024-03-28","current":-2.30713,"twenty":-13.681822,"median":-1.687147,"eighty":-0.384984,"marketCap":32961405},{"date":"2024-04-05","current":-2.345139,"twenty":-13.599124,"median":-1.687694,"eighty":-0.385343,"marketCap":33504426},{"date":"2024-04-12","current":-2.242515,"twenty":-13.499511,"median":-1.697002,"eighty":-0.386402,"marketCap":32038268},{"date":"2024-04-19","current":-2.13229,"twenty":-13.460981,"median":-1.703541,"eighty":-0.386447,"marketCap":30463506},{"date":"2024-04-26","current":-2.033467,"twenty":-13.445945,"median":-1.713103,"eighty":-0.386492,"marketCap":29051650},{"date":"2024-05-03","current":-2.071476,"twenty":-13.381102,"median":-1.721289,"eighty":-0.387146,"marketCap":29594671},{"date":"2024-05-10","current":-2.09048,"twenty":-13.287127,"median":-1.722987,"eighty":-0.389921,"marketCap":29866182},{"date":"2024-05-17","current":-2.386963,"twenty":-13.219465,"median":-1.740977,"eighty":-0.390714,"marketCap":30354901},{"date":"2024-05-24","current":-2.144765,"twenty":-13.182815,"median":-1.750249,"eighty":-0.391829,"marketCap":27274883},{"date":"2024-05-31","current":-2.036818,"twenty":-13.156502,"median":-1.760986,"eighty":-0.393754,"marketCap":25902125},{"date":"2024-06-07","current":-1.921569,"twenty":-13.053129,"median":-1.76629,"eighty":-0.395046,"marketCap":24436510},{"date":"2024-06-14","current":-1.881217,"twenty":-12.977949,"median":-1.769884,"eighty":-0.402584,"marketCap":23923355},{"date":"2024-06-21","current":-1.712293,"twenty":-12.895342,"median":-1.768162,"eighty":-0.40295,"marketCap":21775162},{"date":"2024-06-28","current":-1.737914,"twenty":-12.87469,"median":-1.766929,"eighty":-0.403487,"marketCap":22100975},{"date":"2024-07-05","current":-1.656783,"twenty":-12.852068,"median":-1.76629,"eighty":-0.403729,"marketCap":21069234},{"date":"2024-07-12","current":-1.754994,"twenty":-12.774963,"median":-1.757,"eighty":-0.405314,"marketCap":22318183},{"date":"2024-07-19","current":-1.708023,"twenty":-12.727976,"median":-1.749415,"eighty":-0.406312,"marketCap":21720860},{"date":"2024-07-26","current":-1.690943,"twenty":-12.710632,"median":-1.742068,"eighty":-0.406674,"marketCap":21503651},{"date":"2024-08-02","current":-1.605542,"twenty":-12.696606,"median":-1.737914,"eighty":-0.409519,"marketCap":20417608},{"date":"2024-08-09","current":-1.434782,"twenty":-12.692113,"median":-1.730957,"eighty":-0.411262,"marketCap":18246065},{"date":"2024-08-16","current":-1.596641,"twenty":-12.688507,"median":-1.722624,"eighty":-0.412913,"marketCap":20641231},{"date":"2024-08-23","current":-1.474792,"twenty":-12.655615,"median":-1.721062,"eighty":-0.414802,"marketCap":19065979},{"date":"2024-08-30","current":-1.440674,"twenty":-12.615206,"median":-1.716563,"eighty":-0.415484,"marketCap":18624909},{"date":"2024-09-06","current":-1.407565,"twenty":-12.594531,"median":-1.712293,"eighty":-0.415603,"marketCap":18196875},{"date":"2024-09-13","current":-1.323573,"twenty":-12.570098,"median":-1.711132,"eighty":-0.415629,"marketCap":17111037},{"date":"2024-09-20","current":-1.315128,"twenty":-12.542845,"median":-1.708023,"eighty":-0.415662,"marketCap":17001856},{"date":"2024-09-27","current":-1.155464,"twenty":-12.52217,"median":-1.703753,"eighty":-0.417428,"marketCap":14937733},{"date":"2024-10-04","current":-1.092438,"twenty":-12.454508,"median":-1.699228,"eighty":-0.419145,"marketCap":14122947},{"date":"2024-10-11","current":-1.092438,"twenty":-12.249643,"median":-1.687616,"eighty":-0.419145,"marketCap":14122947},{"date":"2024-10-18","current":-1.848742,"twenty":-12.143451,"median":-1.68691,"eighty":-0.419145,"marketCap":23900373},{"date":"2024-10-25","current":-1.714288,"twenty":-11.823896,"median":-1.679182,"eighty":-0.419145,"marketCap":22162164},{"date":"2024-11-01","current":-1.647061,"twenty":-11.579752,"median":-1.675804,"eighty":-0.419145,"marketCap":21293059},{"date":"2024-11-08","current":-1.42842,"twenty":-11.330783,"median":-1.670088,"eighty":-0.419145,"marketCap":19293905},{"date":"2024-11-15","current":-1.307708,"twenty":-11.015751,"median":-1.659504,"eighty":-0.419145,"marketCap":17663434},{"date":"2024-11-22","current":-1.158831,"twenty":-10.652739,"median":-1.64888,"eighty":-0.419145,"marketCap":15652520},{"date":"2024-11-29","current":-1.166878,"twenty":-10.461096,"median":-1.641011,"eighty":-0.419145,"marketCap":15761218},{"date":"2024-12-06","current":-1.408301,"twenty":-10.285884,"median":-1.633931,"eighty":-0.419145,"marketCap":19022160},{"date":"2024-12-13","current":-1.285578,"twenty":-10.177892,"median":-1.624417,"eighty":-0.419145,"marketCap":17364515},{"date":"2024-12-20","current":-1.227234,"twenty":-9.53593,"median":-1.619001,"eighty":-0.419145,"marketCap":16576454},{"date":"2024-12-27","current":-1.355993,"twenty":-8.696873,"median":-1.609513,"eighty":-0.419145,"marketCap":18315623},{"date":"2025-01-03","current":-1.561203,"twenty":-8.495602,"median":-1.604955,"eighty":-0.419145,"marketCap":21087423},{"date":"2025-01-10","current":-1.470669,"twenty":-3.026512,"median":-1.603162,"eighty":-0.418287,"marketCap":19864570},{"date":"2025-01-17","current":-1.548608,"twenty":-2.846776,"median":-1.596483,"eighty":-0.418287,"marketCap":20917311},{"date":"2025-01-24","current":-1.68976,"twenty":-2.676981,"median":-1.596483,"eighty":-0.418287,"marketCap":22823875},{"date":"2025-01-31","current":-1.573274,"twenty":-2.523112,"median":-1.590338,"eighty":-0.418287,"marketCap":21250470},{"date":"2025-02-07","current":-1.541084,"twenty":-2.484821,"median":-1.580661,"eighty":-0.418287,"marketCap":20815678},{"date":"2025-02-14","current":-1.442744,"twenty":-2.447549,"median":-1.569411,"eighty":-0.418287,"marketCap":19487388},{"date":"2025-02-21","current":-1.054214,"twenty":-2.420526,"median":-1.563205,"eighty":-0.418287,"marketCap":14239445},{"date":"2025-02-28","current":-1.019449,"twenty":-2.382649,"median":-1.54691,"eighty":-0.418287,"marketCap":13769870},{"date":"2025-03-07","current":-0.937526,"twenty":-2.360025,"median":-1.527369,"eighty":-0.417428,"marketCap":12663323},{"date":"2025-03-14","current":-0.965692,"twenty":-2.353872,"median":-1.507106,"eighty":-0.417428,"marketCap":13043767},{"date":"2025-03-21","current":-0.961669,"twenty":-2.341376,"median":-1.477156,"eighty":-0.417428,"marketCap":12989418},{"date":"2025-03-28","current":-0.88575,"twenty":-2.309597,"median":-1.47063,"eighty":-0.417428,"marketCap":11478181},{"date":"2025-04-04","current":-0.720467,"twenty":-2.295403,"median":-1.45956,"eighty":-0.417428,"marketCap":9336320},{"date":"2025-04-11","current":-0.656896,"twenty":-2.279416,"median":-1.448539,"eighty":-0.418287,"marketCap":8512527},{"date":"2025-04-17","current":-0.635875,"twenty":-2.273017,"median":-1.440674,"eighty":-0.418287,"marketCap":8240126},{"date":"2025-04-25","current":-0.673848,"twenty":-2.253321,"median":-1.433778,"eighty":-0.417428,"marketCap":8732205},{"date":"2025-05-02","current":-0.783995,"twenty":-2.247037,"median":-1.423038,"eighty":-0.417428,"marketCap":10159563},{"date":"2025-05-09","current":-0.686562,"twenty":-2.241319,"median":-1.416249,"eighty":-0.417428,"marketCap":8896963},{"date":"2025-05-16","current":-0.725434,"twenty":-2.228343,"median":-1.409031,"eighty":-0.417428,"marketCap":10215032},{"date":"2025-05-23","current":-0.64743,"twenty":-2.215537,"median":-1.401562,"eighty":-0.417428,"marketCap":9116641},{"date":"2025-05-30","current":-0.709036,"twenty":-2.19464,"median":-1.398867,"eighty":-0.417428,"marketCap":9984128},{"date":"2025-06-06","current":-0.711,"twenty":-2.170545,"median":-1.386556,"eighty":-0.417428,"marketCap":10011785},{"date":"2025-06-13","current":-0.75421,"twenty":-2.155823,"median":-1.379144,"eighty":-0.417428,"marketCap":10620236},{"date":"2025-06-20","current":-0.694384,"twenty":-2.142824,"median":-1.376112,"eighty":-0.41657,"marketCap":9777808},{"date":"2025-06-27","current":-0.688413,"twenty":-2.125919,"median":-1.355993,"eighty":-0.41657,"marketCap":9693731},{"date":"2025-07-03","current":-0.683502,"twenty":-2.120684,"median":-1.343922,"eighty":-0.41657,"marketCap":9624589},{"date":"2025-07-11","current":-0.695287,"twenty":-2.10014,"median":-1.328245,"eighty":-0.41657,"marketCap":9790530},{"date":"2025-07-18","current":-0.656005,"twenty":-2.090229,"median":-1.32345,"eighty":-0.41657,"marketCap":9237392},{"date":"2025-07-25","current":-0.758138,"twenty":-2.072574,"median":-1.29622,"eighty":-0.41657,"marketCap":10675549},{"date":"2025-08-01","current":-0.66779,"twenty":-2.063953,"median":-1.275505,"eighty":-0.41657,"marketCap":9403334},{"date":"2025-08-08","current":-0.648149,"twenty":-2.041879,"median":-1.2554,"eighty":-0.41657,"marketCap":9126765},{"date":"2025-08-15","current":-0.710803,"twenty":-2.036714,"median":-1.232343,"eighty":-0.41657,"marketCap":9844691},{"date":"2025-08-22","current":-0.67295,"twenty":-2.032156,"median":-1.215163,"eighty":-0.41657,"marketCap":9320417},{"date":"2025-08-29","current":-0.666641,"twenty":-2.020277,"median":-1.199068,"eighty":-0.41657,"marketCap":9233038},{"date":"2025-09-05","current":-0.63089,"twenty":-2.010984,"median":-1.175426,"eighty":-0.415711,"marketCap":8737891},{"date":"2025-09-12","current":-0.660332,"twenty":-2.005213,"median":-1.166878,"eighty":-0.41657,"marketCap":9145659},{"date":"2025-09-19","current":-0.63089,"twenty":-1.996459,"median":-1.152325,"eighty":-0.41657,"marketCap":8737891},{"date":"2025-09-26","current":-0.607674,"twenty":-1.989224,"median":-1.136556,"eighty":-0.41657,"marketCap":8416337},{"date":"2025-10-03","current":-0.622478,"twenty":-1.97628,"median":-1.122213,"eighty":-0.41657,"marketCap":8621386},{"date":"2025-10-10","current":-0.621217,"twenty":-1.970568,"median":-1.102525,"eighty":-0.41657,"marketCap":8603910},{"date":"2025-10-17","current":-0.647714,"twenty":-1.965805,"median":-1.099345,"eighty":-0.41657,"marketCap":8970901},{"date":"2025-10-24","current":-0.639302,"twenty":-1.95165,"median":-1.092438,"eighty":-0.41657,"marketCap":8854396},{"date":"2025-10-31","current":-0.609861,"twenty":-1.935489,"median":-1.088749,"eighty":-0.41657,"marketCap":8446628},{"date":"2025-11-07","current":-0.504712,"twenty":-1.926839,"median":-1.080616,"eighty":-0.41657,"marketCap":6990313},{"date":"2025-11-14","current":-0.500506,"twenty":-1.917135,"median":-1.077192,"eighty":-0.41657,"marketCap":6932060},{"date":"2025-11-21","current":-0.537234,"twenty":-1.907502,"median":-1.075632,"eighty":-0.41657,"marketCap":7004847},{"date":"2025-11-28","current":-0.609833,"twenty":-1.901304,"median":-1.072855,"eighty":-0.41657,"marketCap":7951447},{"date":"2025-12-05","current":-0.513034,"twenty":-1.887168,"median":-1.064908,"eighty":-0.41657,"marketCap":6689313},{"date":"2025-12-12","current":-0.457374,"twenty":-1.868707,"median":-1.05961,"eighty":-0.41657,"marketCap":5963585},{"date":"2025-12-19","current":-0.440483,"twenty":-1.856187,"median":-1.054712,"eighty":-0.41657,"marketCap":5743343},{"date":"2025-12-26","current":-0.460375,"twenty":-1.842224,"median":-1.054214,"eighty":-0.41657,"marketCap":6002712},{"date":"2026-01-02","current":-0.412847,"twenty":-1.831731,"median":-1.051899,"eighty":-0.415645,"marketCap":5383004},{"date":"2026-01-09","current":-0.504259,"twenty":-1.828167,"median":-1.04168,"eighty":-0.415629,"marketCap":6574907},{"date":"2026-01-16","current":-0.479532,"twenty":-1.806235,"median":-1.035761,"eighty":-0.415629,"marketCap":6252491},{"date":"2026-01-23","current":-0.451586,"twenty":-1.798322,"median":-1.026586,"eighty":-0.415629,"marketCap":5888112},{"date":"2026-01-30","current":-0.31647,"twenty":-1.785978,"median":-1.023773,"eighty":-0.415586,"marketCap":4126364},{"date":"2026-02-06","current":-0.334921,"twenty":-1.785699,"median":-1.021199,"eighty":-0.412847,"marketCap":4366952},{"date":"2026-02-13","current":-0.317918,"twenty":-1.769591,"median":-1.013977,"eighty":-0.406795,"marketCap":4145247},{"date":"2026-02-20","current":-0.438713,"twenty":-1.76629,"median":-1.005981,"eighty":-0.403773,"marketCap":5720260},{"date":"2026-02-24","current":-0.437157,"twenty":-1.759797,"median":-1.002178,"eighty":-0.403773,"marketCap":5699977}],"updateTime":1772034530947},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"APRE\",pageSize:20,pageCount:1,lang_content:\"cn\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"1117590352","title":"Aprea Therapeutics公司：220毫克剂量水平观察到肿瘤缩小50%及CA-125生物标志物显著降低","url":"https://stock-news.laohu8.com/highlight/detail?id=1117590352","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1117590352?lang=zh_cn&edition=fundamental","pubTime":"2026-02-18 21:03","pubTimestamp":1771419793,"startTime":"0","endTime":"0","summary":"在最新临床研究中，Aprea Therapeutics公司采用220毫克剂量治疗方案取得突破性进展。该剂量水平不仅实现肿瘤体积缩小达50%的显著效果，更令人瞩目的是观察到CA-125生物标志物水平的实质性下降。这一双重积极指标为卵巢癌等恶性肿瘤的靶向治疗开辟了新路径。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"1157749062","title":"Aprea Therapeutics宣布Wee1抑制剂Apr-1051取得新进展，ACESOT-1051试验中观察到第二例部分缓解","url":"https://stock-news.laohu8.com/highlight/detail?id=1157749062","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1157749062?lang=zh_cn&edition=fundamental","pubTime":"2026-02-18 21:01","pubTimestamp":1771419674,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics公司近日公布了其Wee1抑制剂候选药物Apr-1051的最新积极临床数据。在正在进行的ACESOT-1051临床试验中，研究观察到了额外的临床活性信号，其中包括第二例达到部分缓解（Partial Response）的病例。这一进展进一步支持了Apr-1051在目标患者群体中的治疗潜力。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"1104981388","title":"Aprea Therapeutics强化DDR抗癌疗法全球专利布局，为管线拓展铺平道路","url":"https://stock-news.laohu8.com/highlight/detail?id=1104981388","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1104981388?lang=zh_cn&edition=fundamental","pubTime":"2026-02-12 10:23","pubTimestamp":1770862993,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics公司近日宣布其DNA损伤应答（DDR）抗癌疗法全球专利组合实现重要拓展，这一战略举措将为公司研发管线的持续增长奠定坚实基础。通过加强知识产权保护，该公司在肿瘤治疗领域的技术壁垒得到进一步巩固，为未来创新疗法的商业化进程提供了有力支撑。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"1134539572","title":"Aprea Therapeutics 宣布在评估Wee1抑制剂APR-1051的ACESOT-1051剂量递增试验中取得早期临床概念验证，首次扫描即观察到部分缓解","url":"https://stock-news.laohu8.com/highlight/detail?id=1134539572","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1134539572?lang=zh_cn&edition=fundamental","pubTime":"2026-01-29 21:31","pubTimestamp":1769693485,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics, Inc. 近日公布，其正在进行的ACESOT-1051剂量递增试验已获得早期临床概念验证数据。该试验旨在评估其Wee1抑制剂候选药物APR-1051。令人鼓舞的是，在首次疗效评估扫描中，已观察到一例患者出现部分缓解，这为药物的抗肿瘤活性提供了初步的积极信号。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0},{"id":"1131666754","title":"Aprea Therapeutics公司：2026年上半年将发布更多进展，年内完成剂量递增研究","url":"https://stock-news.laohu8.com/highlight/detail?id=1131666754","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1131666754?lang=zh_cn&edition=fundamental","pubTime":"2026-01-29 21:29","pubTimestamp":1769693350,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics公司宣布，将在2026年上半年披露更多研发进展，并计划于同年晚些时候完成其正在进行的剂量递增研究。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"1109491456","title":"Aprea Therapeutics, Inc. - 提交股东5.5百万股的再销售招股说明书 - SEC备案","url":"https://stock-news.laohu8.com/highlight/detail?id=1109491456","media":"美股速递","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1109491456?lang=zh_cn&edition=fundamental","pubTime":"2025-12-20 05:14","pubTimestamp":1766178871,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics, Inc. - 提交股东5.5百万股的再销售招股说明书 - SEC备案","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"1147401439","title":"Aprea Therapeutics首席执行官致股东信，强调2025年管线进展及2026年展望","url":"https://stock-news.laohu8.com/highlight/detail?id=1147401439","media":"美股速递","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1147401439?lang=zh_cn&edition=fundamental","pubTime":"2025-12-18 21:30","pubTimestamp":1766064622,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics首席执行官致股东信，强调2025年管线进展及2026年展望","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"2584600792","title":"Aprea Therapeutics, Inc.2025财年第三财季实现净利润-2.97百万美元，同比增加21.43%","url":"https://stock-news.laohu8.com/highlight/detail?id=2584600792","media":"市场透视","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584600792?lang=zh_cn&edition=fundamental","pubTime":"2025-11-18 10:00","pubTimestamp":1763431244,"startTime":"0","endTime":"0","summary":"11月18日，Aprea Therapeutics, Inc.公布财报，公告显示公司2025财年第三财季净利润为-2.97百万美元，同比增加21.43%；其中营业收入为1848.00美元，同比减少99.48%，每股基本收益为-0.47美元。机构评级：截至2025年11月18日，当前有2家机构对Aprea Therapeutics, Inc.目标价做出预测，其中目标均价为10.50美元，其中最低目标价为10.00美元，最高目标价为11.00美元。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2025111810005197700d1b&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, .wx-sou","directOrigin":true},"property":["earning"],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2025111810005197700d1b&s=b","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tencent","symbols":["LENZ","APRE"],"gpt_icon":0},{"id":"1158846295","title":"Aprea Therapeutics公布Acesot-1051试验临床进展，显示出Wee1激酶抑制剂Apr-1051的早期活性信号","url":"https://stock-news.laohu8.com/highlight/detail?id=1158846295","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1158846295?lang=zh_cn&edition=fundamental","pubTime":"2025-10-24 20:30","pubTimestamp":1761309011,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics公布Acesot-1051试验临床进展，显示出Wee1激酶抑制剂Apr-1051的早期活性信号","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"1131289088","title":"Aprea Therapeutics 建立 Atrn-119 的推荐二期剂量 (Rp2d)，考虑联合疗法","url":"https://stock-news.laohu8.com/highlight/detail?id=1131289088","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1131289088?lang=zh_cn&edition=fundamental","pubTime":"2025-10-15 20:03","pubTimestamp":1760529788,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics 建立 Atrn-119 的推荐二期剂量 (Rp2d)，考虑联合疗法","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","APRE"],"gpt_icon":0},{"id":"1127125824","title":"Aprea Therapeutics宣布将在EORTC-NCI-AACR分子靶点与癌症治疗国际会议上发表演讲","url":"https://stock-news.laohu8.com/highlight/detail?id=1127125824","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1127125824?lang=zh_cn&edition=fundamental","pubTime":"2025-10-14 20:04","pubTimestamp":1760443481,"startTime":"0","endTime":"0","summary":"Aprea Therapeutics宣布将在EORTC-NCI-AACR分子靶点与癌症治疗国际会议上发表演讲。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APRE","BK4139"],"gpt_icon":0}],"pageSize":20,"totalPage":1,"pageCount":1,"totalSize":11,"code":"91000000","status":"200"}]}}