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Hoth Therapeutics

0.6900

+0.05007.81%

盘后：0.6698-0.0202-2.93%19:58 EDT

成交量：40.76万

成交额：27.05万

市值：1,319.81万

市盈率：-0.86

高：0.6900

开：0.6324

低：0.6324

收：0.6400

52周最高：2.12

52周最低：0.4894

股本：1,912.76万

流通股本：1,857.40万

量比：0.16

换手率：2.19%

股息：- -

股息率：- -

每股收益(TTM):-0.8041

每股收益(LYR):-0.9032

净资产收益率：-148.85%

总资产收益率：-80.32%

市净率：3.17

市盈率(LYR):-0.76

数据加载中...

总览公司新闻资讯公告

热门话题-Hoth Therapeutics股价下跌，因计划进行品牌重塑并进军人工智能半导体基础设施市场

Hoth Therapeutics旗下Rocket One获VCU人工智能半导体与自旋电子技术独家授权

Hoth Therapeutics 计划持续推进生物技术项目，或考虑将资产注入独立子公司

Hoth Therapeutics公布积极数据：EGFR抑制剂治疗中无患者需减量或停药

Hoth Therapeutics公司HT-001试验取得积极成果：超65%患者报告疼痛与瘙痒显著缓解

Hoth Therapeutics获西班牙授权开展HT-001二期a阶段试验中期数据彰显对癌症患者显著疗效

BUZZ--美国股票走势-贝莱德、MDA Space、Revolution Medicines

BUZZ-临床前数据显示脂肪肝药物性能优于塞马鲁肽，Hoth 公司业绩上升

Hoth Therapeutics 计划将 HT-VA 研究成果推进至更多临床前验证研究

Hoth Therapeutics：GDNF在MAFLD与肥胖模型中显著降低SREBF1并提升PPARα

Hoth Therapeutics公布HT-VA CRADA积极数据：GDNF重构肝脏脂肪代谢机制，关闭脂肪生成基因并激活燃脂通路，效果优于司美格鲁肽

Hoth Therapeutics预计西班牙与波兰监管审批在即试验站点即将启动

匈牙利批准扩大临床试验，因HT-001中期分析达主要终点，患者第六周实现ARIGA≤1

BUZZ--美国股票走势-DexCom、Ocugen、雅诗兰黛

BUZZ-Hoth Therapeutics 公司崛起，因为皮肤疗法在癌症患者中显示出前景

Hoth Therapeutics公布HT-001积极数据：EGFR疗法相关皮肤毒性患者药物暴露量提升约77%且全身吸收极低

Hoth Therapeutics公布积极雌性临床前数据，显示HT-VA在MASLD模型中恢复胆固醇水平并改善脂质代谢

BUZZ-利用人工智能加速罕见癌症药物开发，Hoth Therapeutics 公司崛起

Hoth Therapeutics公司公布Cleer-001中期数据：队列患者100%达到主要疗效终点

Hoth Therapeutics 因患者需求增加，增设新临床中心加速 HT-001 试验入组

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宣布，公司将继续推进其生物技术项目。同时，公司正考虑将部分资产置于一个独立的子公司中。这一举措旨在优化资产结构，可能为特定项目或技术平台的未来发展提供更清晰的战略聚焦和运营灵活性。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1171422639","title":"Hoth Therapeutics公布积极数据：EGFR抑制剂治疗中无患者需减量或停药","url":"https://stock-news.laohu8.com/highlight/detail?id=1171422639","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1171422639?lang=zh_cn&edition=fundamental","pubTime":"2026-05-06 04:18","pubTimestamp":1778012297,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics Inc宣布了一项关于其EGFR抑制剂疗法的积极进展。在相关临床观察中，接受该治疗方案的患者群体表现出良好的耐受性，目前没有患者因不良反应而需要降低药物剂量或中止治疗。\n这一结果具有重要意义，因为它初步表明该疗法可能在维持预期疗效的同时，有效控制了潜在的副作用。对于依赖EGFR抑制剂路径的癌症治疗而言，维持足额剂量治疗的连续性通常是影响疗效的关键因素之一。此次数据的公布为Hoth Therapeutics的后续临床开发提供了支持。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1131399950","title":"Hoth Therapeutics公司HT-001试验取得积极成果：超65%患者报告疼痛与瘙痒显著缓解","url":"https://stock-news.laohu8.com/highlight/detail?id=1131399950","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1131399950?lang=zh_cn&edition=fundamental","pubTime":"2026-05-06 04:18","pubTimestamp":1778012297,"startTime":"0","endTime":"0","summary":"在Hoth Therapeutics公司最新公布的HT-001临床试验数据中，超过65%的受试者反馈其疼痛与瘙痒症状获得显著改善。该试验结果展现了候选药物在缓解患者临床症状方面的潜力，为后续研发进程提供了重要数据支持。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1128744078","title":"Hoth Therapeutics获西班牙授权开展HT-001二期a阶段试验 中期数据彰显对癌症患者显著疗效","url":"https://stock-news.laohu8.com/highlight/detail?id=1128744078","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1128744078?lang=zh_cn&edition=fundamental","pubTime":"2026-05-06 04:17","pubTimestamp":1778012240,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics宣布，其创新疗法HT-001已获得西班牙监管机构批准开展二期a阶段临床试验。此次欧洲授权标志着该药物研发进程中的重要里程碑。\n最新披露的中期数据显示，HT-001在癌症患者群体中表现出令人鼓舞的治疗效果。试验结果初步证实了该疗法在控制肿瘤进展和改善患者临床症状方面的潜力。\n获得西班牙药监部门的认可，为Hoth Therapeutics在欧洲市场进一步推进临床研究奠定了坚实基础。公司计划基于现有数据优化后续试验方案，加速HT-001的全球化开发进程。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627426865","title":"BUZZ--美国股票走势-贝莱德、MDA Space、Revolution Medicines","url":"https://stock-news.laohu8.com/highlight/detail?id=2627426865","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627426865?lang=zh_cn&edition=fundamental","pubTime":"2026-04-15 02:05","pubTimestamp":1776189931,"startTime":"0","endTime":"0","summary":".N美国东部时间13:30，道琼斯工业平均指数.DJI上涨0.57%，报48,491.58点。标普500指数.SPX上涨1.10%，报6,961.48点；纳斯达克综合指数.IXIC上涨1.81%，报23,602.14点。nL4N40X126 ** 福特汽车公司F.N：BUZZ - 因预期盈利增长，瑞银将其评级上调至 \"买入 \"后上涨 nL4N40X13T ** Galmed Pharmaceuticals Ltd GLMD.O:BUZZ - 因合作测试脑癌药物而上涨。nL4N40X14P ** Clearmind Medicine Inc CMND.O:BUZZ - 在酒精成瘾药物早期试验显示安全性后上涨 nL4N40X15J ** 通用汽车公司GM.N:BUZZ - 因德意志银行将其评级上调至 \"买入 \"而上涨 nL4N40X15B ** T1 Energy Inc TE.N:BUZZ -计划发行1.25亿美元可转换债券，","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"37684715aaf54a73b9fe52ee56a263cc","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nL4T40X1VL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AVNS","RGTI","BKR","JNJ","TE","AVXL","CAT","GAME","BLK","XOM","RIOT","RVMD","DAL","UAL","QBTS","CRDO","GM","SPOT","NEM","QUBT","CVX","MSTR","DOW","BTBT","KMX","F","NNOX","TSLA","HOTH","ALLO","TVTX","LCID","BTCS","IONQ","GLMD","LUV","MARA","COIN","CDE","GSAT","EAF","HL","GRCE","ILMN","SBET","WMG","CRWV","ACI","CMPS","HAL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627448457","title":"BUZZ-临床前数据显示脂肪肝药物性能优于塞马鲁肽，Hoth 公司业绩上升","url":"https://stock-news.laohu8.com/highlight/detail?id=2627448457","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627448457?lang=zh_cn&edition=fundamental","pubTime":"2026-04-14 19:20","pubTimestamp":1776165644,"startTime":"0","endTime":"0","summary":"BUZZ-临床前数据显示脂肪肝药物性能优于塞马鲁肽，Hoth 公司业绩上升4月14日 - ** 生物技术公司Hoth Therapeutics HOTH.O股价盘前上涨50%至0.76美元** 该公司称其实验性药物GDNF在代谢相关性脂肪肝的临床前研究中取得了令人鼓舞的结果，这种疾病的特征是肝脏脂肪过度堆积，可能导致瘢痕形成和肝功能衰竭。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"37684715aaf54a73b9fe52ee56a263cc","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nL4T40X13Q:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"1149943911","title":"Hoth Therapeutics 计划将 HT-VA 研究成果推进至更多临床前验证研究","url":"https://stock-news.laohu8.com/highlight/detail?id=1149943911","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1149943911?lang=zh_cn&edition=fundamental","pubTime":"2026-04-14 19:05","pubTimestamp":1776164704,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics 宣布将把其 HT-VA 项目的关键发现推进至额外的临床前验证研究阶段。这一举措旨在进一步评估该候选疗法的有效性与安全性，为后续开发奠定基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1188422004","title":"Hoth Therapeutics：GDNF在MAFLD与肥胖模型中显著降低SREBF1并提升PPARα","url":"https://stock-news.laohu8.com/highlight/detail?id=1188422004","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1188422004?lang=zh_cn&edition=fundamental","pubTime":"2026-04-14 05:25","pubTimestamp":1776115540,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics公司公布的研究数据显示，其关注的胶质细胞源性神经营养因子（GDNF）在代谢相关脂肪性肝病（MAFLD）与肥胖实验模型中表现出显著作用。该因子能够有效降低固醇调节元件结合转录因子1（SREBF1）的表达水平，同时促进过氧化物酶体增殖物激活受体α（PPARα）的活性提升。\n这一发现为开发针对代谢紊乱相关疾病的创新疗法提供了新的分子机制依据，突显了GDNF在调节脂质代谢通路中的潜在治疗价值。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1171005149","title":"Hoth Therapeutics公布HT-VA CRADA积极数据：GDNF重构肝脏脂肪代谢机制，关闭脂肪生成基因并激活燃脂通路，效果优于司美格鲁肽","url":"https://stock-news.laohu8.com/highlight/detail?id=1171005149","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1171005149?lang=zh_cn&edition=fundamental","pubTime":"2026-04-14 05:25","pubTimestamp":1776115524,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics最新发布的HT-VA合作研发协议数据取得突破性进展。研究显示，胶质细胞源性神经营养因子能够重塑肝脏脂肪代谢系统，成功抑制脂肪合成基因的表达，同时激活多条脂肪分解代谢通路。值得注意的是，该疗法在临床前研究中表现出优于糖尿病药物司美格鲁肽的代谢调节能力。\n实验数据揭示，GDNF通过调控肝脏细胞能量代谢的关键节点，实现脂肪代谢的双向调节：一方面有效阻断新生脂肪的积累途径，另一方面显著提升脂肪酸氧化效率。这种独特的作用机制为治疗代谢性疾病提供了新的方向，尤其对非酒精性脂肪肝等疾病具有潜在治疗价值。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1131915652","title":"Hoth Therapeutics预计西班牙与波兰监管审批在即 试验站点即将启动","url":"https://stock-news.laohu8.com/highlight/detail?id=1131915652","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1131915652?lang=zh_cn&edition=fundamental","pubTime":"2026-04-01 20:17","pubTimestamp":1775045833,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics近日透露，其针对特应性皮炎的新型疗法已向西班牙与波兰监管机构提交审批申请，预计短期内将获得通过。这意味着该公司位于两国的临床试验站点有望迅速投入运营，加速推进其创新药物的国际化布局。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1118216933","title":"匈牙利批准扩大临床试验，因HT-001中期分析达主要终点，患者第六周实现ARIGA≤1","url":"https://stock-news.laohu8.com/highlight/detail?id=1118216933","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1118216933?lang=zh_cn&edition=fundamental","pubTime":"2026-04-01 20:17","pubTimestamp":1775045830,"startTime":"0","endTime":"0","summary":"匈牙利监管机构已批准扩大HT-001的临床试验规模。这一决定基于该药物在中期分析中成功达到主要研究终点——数据显示，参与试验的患者在第六周时ARIGA评分已降至≤1水平。\nHT-001由生物制药公司Hoth Therapeutics研发，此次中期分析结果为其疗效提供了有力支持。ARIGA指标是评估治疗反应的关键参数，数值≤1代表临床症状获得显著改善。试验数据的积极进展，为后续研究奠定了坚实基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621060385","title":"BUZZ--美国股票走势-DexCom、Ocugen、雅诗兰黛","url":"https://stock-news.laohu8.com/highlight/detail?id=2621060385","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621060385?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 21:11","pubTimestamp":1774357883,"startTime":"0","endTime":"0","summary":"nL4N40C0TS ** 阿拉斯加航空集团ALK.N:BUZZ - 由于长期趋势良好，BMO首次给予阿拉斯加航空“跑赢大盘”评级。nL4N40C0UK ** Karyopharm Therapeutics Inc KPTI.O:BUZZ - 血液癌症药物在研究中达到两个主要目标之一，该公司股价大涨 nL6N40C0RF ** DexCom Inc DXCM.O:BUZZ - 因Evercore上调目标价，看好其糖尿病设备有望获得保险覆盖而上涨 nL4N40C0PS ** JetBlue Airways Corp JBLU.O:BUZZ - BMO开始对捷蓝航空进行 \"市场表现 \"评级。nL4N40C0ZA ** Arthur J. Gallagher & Co JG.N:BUZZ - BMO将Gallagher的评级上调至 \"跑赢大盘\"，原因是人工智能带来了生产力方面的好处。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"37684715aaf54a73b9fe52ee56a263cc","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260324:nL4T40C167:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BBYY","RIO.UK","LU0823426480.USD","LU2778985437.USD","ALK","FTAI","LU0251144936.SGD","LU2476274308.USD","SCCO","AJG","CNXC","ALBmain","JBLU","OCGN","ECL","LU0329678170.USD","RIO.AU","LU0345775950.USD","APO","JEF","DXCM","LU2257852520.SGD","BABX","LU1166156734.SGD","SFD","HOTH","89988","EVR","FCX","LU0823417737.USD","LU0384037296.USD","LU1196710864.SGD","KPTI","ARES","EL","BABU","KBAB","BABW","BABO","FCXG","LU0819121731.USD","LU0797268264.HKD","00288","LU0787776722.HKD","HBBD.SI","BHP.AU","LU0577902611.USD","WT"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2621049064","title":"BUZZ-Hoth Therapeutics 公司崛起，因为皮肤疗法在癌症患者中显示出前景","url":"https://stock-news.laohu8.com/highlight/detail?id=2621049064","media":"路透中文","labels":["shareholding","productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621049064?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 20:22","pubTimestamp":1774354948,"startTime":"0","endTime":"0","summary":"由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"37684715aaf54a73b9fe52ee56a263cc","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260324:nL4S40C12C:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1188249439","title":"Hoth Therapeutics公布HT-001积极数据：EGFR疗法相关皮肤毒性患者药物暴露量提升约77%且全身吸收极低","url":"https://stock-news.laohu8.com/highlight/detail?id=1188249439","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1188249439?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 20:14","pubTimestamp":1774354455,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics最新公布的临床研究数据显示，其针对EGFR抑制剂引发皮肤毒性的抗癌患者研发的HT-001疗法，在药代动力学、安全性及临床活性方面表现积极。数据显示，该疗法可使局部药物暴露量提升约77%，同时全身系统性吸收维持在极低水平。\n该结果印证了HT-001通过局部给药精准靶向皮肤毒性的治疗策略，在维持有效局部药物浓度的同时，最大限度降低了全身性副作用风险。这一特性对于需要长期接受EGFR靶向治疗的癌症患者具有重要临床意义。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1140710087","title":"Hoth Therapeutics公布积极雌性临床前数据，显示HT-VA在MASLD模型中恢复胆固醇水平并改善脂质代谢","url":"https://stock-news.laohu8.com/highlight/detail?id=1140710087","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1140710087?lang=zh_cn&edition=fundamental","pubTime":"2026-03-10 20:14","pubTimestamp":1773144894,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics发布的最新雌性临床前研究数据显示，其候选药物HT-VA在代谢相关脂肪肝病（MASLD）动物模型中表现出显著疗效。实验结果表明，HT-VA能够有效恢复机体的胆固醇平衡，并优化脂质代谢通路。这一突破为开发针对代谢性肝病的新型疗法提供了有力支持。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616555621","title":"BUZZ-利用人工智能加速罕见癌症药物开发，Hoth Therapeutics 公司崛起","url":"https://stock-news.laohu8.com/highlight/detail?id=2616555621","media":"路透中文","labels":["shareholding","productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616555621?lang=zh_cn&edition=fundamental","pubTime":"2026-03-04 21:48","pubTimestamp":1772632097,"startTime":"0","endTime":"0","summary":"BUZZ-利用人工智能加速罕见癌症药物开发，Hoth Therapeutics 公司崛起3月4日 - ** Hoth Therapeutics HOTH.O股价盘前上涨4.33%至1.04美元** 该公司称正在使用OpenAI工具帮助开发治疗由KIT基因缺陷引起的罕见癌症的药物，而该缺陷可推动肿瘤生长** 该公司表示，其实验性药物 HT-KIT 的早期测试在实验室和动物实验中大幅降低了 KIT 基因的水平，而且没有出现严重的副作用。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260304:nL4S3ZS1AN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1189620458","title":"Hoth Therapeutics公司公布Cleer-001中期数据：队列患者100%达到主要疗效终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1189620458","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1189620458?lang=zh_cn&edition=fundamental","pubTime":"2026-02-25 05:17","pubTimestamp":1771967841,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics公司最新发布的Cleer-001中期临床试验数据显示，该研究队列中的所有患者均成功达到了预设的主要疗效终点，这一结果标志着候选疗法在目标患者群体中展现出显著的临床潜力。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1158626179","title":"Hoth Therapeutics 因患者需求增加，增设新临床中心加速 HT-001 试验入组","url":"https://stock-news.laohu8.com/highlight/detail?id=1158626179","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1158626179?lang=zh_cn&edition=fundamental","pubTime":"2026-02-25 05:15","pubTimestamp":1771967741,"startTime":"0","endTime":"0","summary":"随着患者需求显著上升，Hoth Therapeutics 正通过增设新的临床研究中心，全力加快其核心候选药物 HT-001 的临床试验患者入组进程。\n这一战略举措旨在高效应对日益增长的患者参与意愿，确保试验能够按计划甚至提前推进，从而为后续的药物开发奠定坚实基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":2,"pageCount":1,"totalSize":27,"code":"91000000","status":"200"}]}}