美股详情

本页面由Tiger Trade Technology Pte. Ltd.提供服务

Ionis Pharmaceuticals, Inc

61.53

+1.792.99%

成交量：116.59万

成交额：7,110.62万

市值：102.24亿

市盈率：-17.68

高：61.53

开：60.60

低：59.70

收：59.74

52周最高：86.74

52周最低：41.71

股本：1.66亿

流通股本：1.62亿

量比：0.54

换手率：0.72%

股息：- -

股息率：- -

每股收益(TTM):-3.4800

每股收益(LYR):-2.3812

净资产收益率：-105.50%

总资产收益率：-12.42%

市净率：23.25

市盈率(LYR):-25.84

数据加载中...

总览公司新闻资讯公告

美国研究综述-艾伯维、亚马逊、伊利姆纳

异动解读｜Ionis Pharmaceuticals盘中上涨5.39%，报56.92美元

异动解读｜Ionis Pharmaceuticals盘中下跌5.16%，财报前机构偏空叠加心血管管线挫折余波

异动解读｜Ionis Pharmaceuticals盘前下跌6.35%，财报前机构偏空叠加管线挫折余波

财报前瞻｜Ionis Pharmaceuticals, Inc本季度营收或小幅回落，机构观点偏谨慎

Biogen公布Celia二期数据：Diranersen在早期阿尔茨海默病中展现显著临床获益及强劲Tau蛋白降低

“木头姐”再度调整持仓，加码Meta、减持AMD

老虎资讯综合

异动解读｜Ionis Pharmaceuticals盘中下跌6.04%，核心管线三期试验失败余震延续

美国研究综述-贝莱德、彭纳特集团、威斯尔豪瑟公司

异动解读｜Ionis Pharmaceuticals盘中下跌20.03%，核心管线Eplontersen三期心脏试验未达主要终点

联合开发心脏药物III期试验未达主要终点，阿斯利康与Ionis股价暴跌

BUZZ——美国股市动态-Levi、Ionis Pharmaceuticals、Gloo Holdings

联合开发心脏药物III期试验未达主要终点阿斯利康(AZN.US)与Ionis(IONS.US)股价暴跌

受中东局势持续紧张影响，伦敦富时100指数走低，阿斯利康拖累大盘

与阿斯利康合作研发药物三期心脏病试验失败，Ionis Pharmaceuticals盘前股价大跌13.8%

异动解读｜Ionis Pharmaceuticals盘前下跌14.75%，核心管线三期试验未达主要终点

阿斯利康因心脏病药物晚期临床试验失败，成为富时100指数中跌幅最大的个股

阿斯利康与Ionis合作研发的药物在晚期心脏病临床试验中未能达到主要目标

Ionis制药Eplontersen三期心脏转归试验至第140周未达主要终点

Eplontersen治疗转甲状腺素蛋白介导淀粉样心肌病成人患者的Cardio-Ttransform三期试验最新进展

{"basename":"/hans","ssrTDKData":{"titleTemplate":"%s - 老虎证券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎证券,老虎证券开户,老虎券商,老虎证券官网,老虎证券app,tigertrade老虎证券,股票,炒股,新加坡股票交易平台,投资,投资理财","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.itiger.com/hans/stock/IONS/news"},"companyName":"老虎证券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"IONS","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","market":"US","secType":"STK","nameCN":"Ionis Pharmaceuticals, Inc","latestPrice":61.525,"timestamp":1787597251913,"preClose":59.74,"halted":0,"volume":1165876,"delay":0,"changeRate":0.02987947773685967,"floatShares":161921007,"shares":166184322,"eps":-3.48,"marketStatus":"交易中","change":1.785,"latestTime":"08-24 14:47:33 EDT","open":60.6,"high":61.53,"low":59.7,"amount":71106229.27828,"amplitude":0.030633,"askPrice":61.53,"askSize":11,"bidPrice":61.51,"bidSize":340,"shortable":3,"etf":0,"ttmEps":-3.48,"tradingStatus":2,"nextMarketStatus":{"tag":"盘后交易","tradingStatus":3,"beginTime":1787601600000},"marketStatusCode":2,"adr":0,"adrRate":0,"exchange":"NASDAQ","adjPreClose":59.74,"preHourTrading":{"tag":"盘前","latestPrice":60.23,"preClose":59.74,"latestTime":"09:29 EDT","volume":2365,"amount":143331.88925,"timestamp":1787578199986,"change":0.49,"changeRate":0.008202,"amplitude":0.014563},"postHourTrading":{"tag":"盘后","latestPrice":60.653,"preClose":59.74,"latestTime":"19:58 EDT","volume":111370,"amount":6657464.6882,"timestamp":1787356733552,"change":0.913,"changeRate":0.015283,"amplitude":0.021021},"volumeRatio":0.542467,"impliedVol":0.5591,"impliedVolPercentile":0.9602},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","floatShares":161921007,"roa":"-12.42%","roe":"-105.50%","lyrEps":-2.38125,"volumeRatio":0.542467,"shares":166184322,"dividePrice":0,"high":61.53,"amplitude":0.030633,"preClose":59.74,"low":59.7,"week52Low":41.705,"pbRate":"23.25","psRate":"11.70","week52High":86.74,"institutionHeld":0.98,"latestPrice":61.525,"committee":0.937322,"eps":-3.48,"divideRate":0,"volume":1165876,"delay":0,"ttmEps":-3.48,"open":60.6,"prevYearClose":79.11,"prevWeekClose":59.74,"prevMonthClose":51.77,"prevQuarterClose":79.29,"fiveDayClose":58.63,"twentyDayClose":55.96,"sixtyDayClose":77.33},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/IONS\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-29","symbol":"IONS","fiscalQuarterEnding":"2026/06","expectedEps":-1.09,"name":null,"time":"盘前","type":"earning","dateTimestamp":1785297600000,"reportTimeType":"pre","actualEps":-0.7},{"market":"US","date":"2026-04-29","symbol":"IONS","fiscalQuarterEnding":"2026/03","expectedEps":-0.89,"name":null,"time":"盘前","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"pre","actualEps":-0.56},{"market":"US","date":"2026-02-25","symbol":"IONS","fiscalQuarterEnding":"2025/12","expectedEps":-1.31,"name":null,"time":"盘前","type":"earning","dateTimestamp":1771995600000,"reportTimeType":"pre","actualEps":-1.41},{"market":"US","date":"2025-10-29","symbol":"IONS","fiscalQuarterEnding":"2025/09","expectedEps":-1.23,"name":null,"time":"盘前","type":"earning","dateTimestamp":1761710400000,"reportTimeType":"pre","actualEps":-0.8},{"market":"US","date":"2025-07-30","symbol":"IONS","fiscalQuarterEnding":"2025/06","expectedEps":-0.11,"name":null,"time":"盘前","type":"earning","dateTimestamp":1753848000000,"reportTimeType":"pre","actualEps":0.7}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"IONS\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"IONS\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2308,"buy":0.5385,"hold":0.2308,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5385,"analysts":26,"updateTime":1787112000000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/IONS\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"IONS","date":"2026-08-21","current":-17.537356,"percent":0.568755,"low":-1664.931905,"twenty":-46.83029,"median":-17.93492,"eighty":-11.52511,"high":882.260453,"avg":-65.086095,"sd":366.247252,"marketCap":9764990760},"quantilePoints":[{"date":"2021-08-27","current":-10.175088,"twenty":-43.823694,"median":23.306229,"eighty":141.027241,"marketCap":5593683271},{"date":"2021-09-03","current":-10.146845,"twenty":-43.823694,"median":22.806307,"eighty":135.009304,"marketCap":5578157024},{"date":"2021-09-10","current":-9.266185,"twenty":-43.823694,"median":22.273726,"eighty":92.336284,"marketCap":5094020420},{"date":"2021-09-17","current":-9.553748,"twenty":-43.823694,"median":22.105712,"eighty":90.484478,"marketCap":5252105842},{"date":"2021-09-24","current":-9.294428,"twenty":-43.823694,"median":21.894477,"eighty":89.822908,"marketCap":5109546667},{"date":"2021-10-01","current":-8.61917,"twenty":-43.823694,"median":21.739571,"eighty":88.160122,"marketCap":4738328221},{"date":"2021-10-08","current":-8.752681,"twenty":-43.823694,"median":21.475528,"eighty":87.371554,"marketCap":4811725024},{"date":"2021-10-15","current":-9.012001,"twenty":-43.823694,"median":21.145012,"eighty":86.264015,"marketCap":4954284199},{"date":"2021-10-22","current":-7.815535,"twenty":-43.823694,"median":21.004285,"eighty":84.663252,"marketCap":4296535927},{"date":"2021-10-29","current":-8.182691,"twenty":-43.823694,"median":20.82218,"eighty":83.19244,"marketCap":4498377135},{"date":"2021-11-05","current":-7.827936,"twenty":-43.823694,"median":20.669316,"eighty":82.070133,"marketCap":4757365405},{"date":"2021-11-12","current":-7.595584,"twenty":-43.823694,"median":20.616507,"eighty":76.079084,"marketCap":4616155390},{"date":"2021-11-19","current":-7.432938,"twenty":-43.823694,"median":20.366546,"eighty":75.49578,"marketCap":4517308379},{"date":"2021-11-26","current":-6.749823,"twenty":-43.823694,"median":20.294106,"eighty":74.547727,"marketCap":4102150935},{"date":"2021-12-03","current":-6.131767,"twenty":-43.823694,"median":20.173015,"eighty":74.030875,"marketCap":3726532295},{"date":"2021-12-10","current":-6.847411,"twenty":-43.823694,"median":20.114106,"eighty":72.607318,"marketCap":4161459142},{"date":"2021-12-17","current":-7.542143,"twenty":-43.823694,"median":20.025743,"eighty":70.436541,"marketCap":4583677086},{"date":"2021-12-23","current":-7.600231,"twenty":-43.823694,"median":19.891562,"eighty":60.214071,"marketCap":4618979590},{"date":"2021-12-31","current":-7.070469,"twenty":-43.823694,"median":19.796653,"eighty":53.012098,"marketCap":4297020756},{"date":"2022-01-07","current":-7.058851,"twenty":-43.611673,"median":19.749198,"eighty":51.923862,"marketCap":4289960255},{"date":"2022-01-14","current":-7.686201,"twenty":-43.611673,"median":19.64938,"eighty":51.147099,"marketCap":4671227296},{"date":"2022-01-21","current":-6.942675,"twenty":-43.611673,"median":19.61175,"eighty":50.934296,"marketCap":4219355248},{"date":"2022-01-28","current":-7.360909,"twenty":-43.611673,"median":19.468798,"eighty":50.847883,"marketCap":4473533275},{"date":"2022-02-04","current":-7.319085,"twenty":-43.611673,"median":19.28882,"eighty":50.5876,"marketCap":4448115472},{"date":"2022-02-11","current":-7.639731,"twenty":-43.611673,"median":19.164904,"eighty":50.143461,"marketCap":4642985293},{"date":"2022-02-18","current":-7.497996,"twenty":-43.611673,"median":18.965356,"eighty":49.908881,"marketCap":4556847184},{"date":"2022-02-25","current":-157.459445,"twenty":-44.533501,"median":18.77393,"eighty":49.713145,"marketCap":4502867744},{"date":"2022-03-04","current":-160.035874,"twenty":-45.829592,"median":18.155386,"eighty":49.32903,"marketCap":4576545882},{"date":"2022-03-11","current":-159.49086,"twenty":-46.633425,"median":-6.144547,"eighty":48.69515,"marketCap":4560960122},{"date":"2022-03-18","current":-174.652153,"twenty":-47.12015,"median":-6.881102,"eighty":48.427938,"marketCap":4994527626},{"date":"2022-03-25","current":-181.687786,"twenty":-47.927671,"median":-7.000763,"eighty":48.265452,"marketCap":5195725619},{"date":"2022-04-01","current":-192.736702,"twenty":-48.230031,"median":-7.040263,"eighty":47.833218,"marketCap":5511691480},{"date":"2022-04-08","current":-198.781401,"twenty":-48.689101,"median":-7.082087,"eighty":47.228668,"marketCap":5684551727},{"date":"2022-04-14","current":-202.992871,"twenty":-49.716018,"median":-7.119262,"eighty":46.918857,"marketCap":5804987145},{"date":"2022-04-22","current":-206.852389,"twenty":-50.435043,"median":-7.237762,"eighty":46.570634,"marketCap":5915357781},{"date":"2022-04-29","current":-182.216483,"twenty":-51.591015,"median":-7.300497,"eighty":46.245658,"marketCap":5210844764},{"date":"2022-05-06","current":-1322.183946,"twenty":-128.214398,"median":-7.341159,"eighty":45.925265,"marketCap":5147262100},{"date":"2022-05-13","current":-1314.170709,"twenty":-130.326929,"median":-7.37485,"eighty":45.90793,"marketCap":5116066572},{"date":"2022-05-20","current":-1438.375868,"twenty":-130.86667,"median":-7.37485,"eighty":45.90793,"marketCap":5599597254},{"date":"2022-05-27","current":-1370.6276,"twenty":-132.625178,"median":-7.37485,"eighty":45.90793,"marketCap":5335853246},{"date":"2022-06-03","current":-1316.720376,"twenty":-134.128325,"median":-7.37485,"eighty":45.90793,"marketCap":5125992422},{"date":"2022-06-10","current":-1266.091293,"twenty":-137.45382,"median":-7.37485,"eighty":45.90793,"marketCap":4928893405},{"date":"2022-06-17","current":-1284.303193,"twenty":-139.005646,"median":-7.37485,"eighty":45.90793,"marketCap":4999792332},{"date":"2022-06-24","current":-1429.634156,"twenty":-139.862338,"median":-7.360909,"eighty":45.909339,"marketCap":5565565769},{"date":"2022-07-01","current":-1386.289834,"twenty":-141.353878,"median":-7.360909,"eighty":45.909339,"marketCap":5396826323},{"date":"2022-07-08","current":-1353.144176,"twenty":-142.456573,"median":-7.360909,"eighty":45.909339,"marketCap":5267790276},{"date":"2022-07-15","current":-1431.819584,"twenty":-143.808127,"median":-7.360909,"eighty":45.909339,"marketCap":5574073640},{"date":"2022-07-22","current":-1387.746786,"twenty":-144.656772,"median":-7.360909,"eighty":45.909339,"marketCap":5402498237},{"date":"2022-07-29","current":-1368.077934,"twenty":-146.022974,"median":-7.360909,"eighty":45.909339,"marketCap":5325927396},{"date":"2022-08-05","current":-1664.567667,"twenty":-147.819198,"median":-7.360909,"eighty":45.909339,"marketCap":6480161927},{"date":"2022-08-12","current":-222.342663,"twenty":-148.698169,"median":-7.360909,"eighty":45.909339,"marketCap":6259613005},{"date":"2022-08-19","current":-221.838485,"twenty":-149.407406,"median":-7.360909,"eighty":45.909339,"marketCap":6245418872},{"date":"2022-08-26","current":-213.519542,"twenty":-149.883165,"median":-7.360909,"eighty":45.909339,"marketCap":6011215664},{"date":"2022-09-02","current":-218.006729,"twenty":-150.165357,"median":-7.360909,"eighty":45.909339,"marketCap":6137543455},{"date":"2022-09-09","current":-236.157151,"twenty":-151.092649,"median":-7.360909,"eighty":45.909339,"marketCap":6648532271},{"date":"2022-09-16","current":-233.585841,"twenty":-153.529951,"median":-7.360909,"eighty":45.909339,"marketCap":6576142189},{"date":"2022-09-23","current":-217.956312,"twenty":-156.46647,"median":-7.360909,"eighty":45.909339,"marketCap":6136124041},{"date":"2022-09-30","current":-222.998095,"twenty":-157.969129,"median":-7.360909,"eighty":45.909339,"marketCap":6278065379},{"date":"2022-10-07","current":-231.569128,"twenty":-159.577078,"median":-7.360909,"eighty":45.909339,"marketCap":6519365654},{"date":"2022-10-14","current":-233.737095,"twenty":-160.082841,"median":-7.360909,"eighty":45.909339,"marketCap":6580400429},{"date":"2022-10-21","current":-226.62818,"twenty":-160.43291,"median":-7.360909,"eighty":45.909339,"marketCap":6380263143},{"date":"2022-10-28","current":-224.913973,"twenty":-161.94987,"median":-7.360909,"eighty":45.909339,"marketCap":6332003088},{"date":"2022-11-04","current":-209.486115,"twenty":-162.370971,"median":-7.360909,"eighty":45.909339,"marketCap":5897662593},{"date":"2022-11-11","current":839.185498,"twenty":-162.756411,"median":-7.319085,"eighty":46.031035,"marketCap":6143677032},{"date":"2022-11-18","current":836.080997,"twenty":-162.756411,"median":-7.284232,"eighty":46.34415,"marketCap":6120948978},{"date":"2022-11-25","current":806.394204,"twenty":-162.756411,"median":-7.219174,"eighty":46.64061,"marketCap":5903611964},{"date":"2022-12-02","current":782.334319,"twenty":-162.756411,"median":-7.102998,"eighty":47.141347,"marketCap":5727469547},{"date":"2022-12-09","current":727.617484,"twenty":-162.756411,"median":-7.058851,"eighty":47.387939,"marketCap":5326887600},{"date":"2022-12-16","current":750.125118,"twenty":-162.756411,"median":-7.014704,"eighty":48.047842,"marketCap":5491665989},{"date":"2022-12-23","current":740.423552,"twenty":-162.756411,"median":-6.972881,"eighty":48.293594,"marketCap":5420640821},{"date":"2022-12-30","current":732.85633,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5365241190},{"date":"2023-01-06","current":786.214945,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5755879614},{"date":"2023-01-13","current":773.214846,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5660705889},{"date":"2023-01-20","current":790.871697,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5789971695},{"date":"2023-01-27","current":776.513379,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5684854446},{"date":"2023-02-03","current":793.976198,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5812699749},{"date":"2023-02-10","current":756.722183,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5539963104},{"date":"2023-02-17","current":748.96093,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5483142969},{"date":"2023-02-24","current":-18.915876,"twenty":-162.756411,"median":-6.942675,"eighty":48.318169,"marketCap":5102028010},{"date":"2023-03-03","current":-19.398181,"twenty":-162.756411,"median":-7.010057,"eighty":48.167441,"marketCap":5232116143},{"date":"2023-03-10","current":-17.998968,"twenty":-162.756411,"median":-7.047233,"eighty":47.522459,"marketCap":4854717602},{"date":"2023-03-17","current":-18.645574,"twenty":-162.756411,"median":-7.096027,"eighty":47.151665,"marketCap":5029121473},{"date":"2023-03-24","current":-17.993668,"twenty":-162.756411,"median":-7.188968,"eighty":46.719576,"marketCap":4853288062},{"date":"2023-03-31","current":-18.942377,"twenty":-162.739653,"median":-7.283071,"eighty":46.447558,"marketCap":5109175709},{"date":"2023-04-06","current":-19.392881,"twenty":-162.739653,"median":-7.309791,"eighty":46.139197,"marketCap":5230686603},{"date":"2023-04-14","current":-19.906986,"twenty":-162.756411,"median":-7.388791,"eighty":45.881909,"marketCap":5369351977},{"date":"2023-04-21","current":-19.158378,"twenty":-162.756411,"median":-7.484055,"eighty":45.586713,"marketCap":5167435947},{"date":"2023-04-28","current":-18.691747,"twenty":-162.756411,"median":-7.542143,"eighty":45.238708,"marketCap":5041575343},{"date":"2023-05-05","current":-15.654507,"twenty":-162.722895,"median":-7.581643,"eighty":45.096531,"marketCap":5148454369},{"date":"2023-05-12","current":-15.484823,"twenty":-162.005118,"median":-7.581643,"eighty":45.096531,"marketCap":5092648444},{"date":"2023-05-19","current":-15.937315,"twenty":-160.611822,"median":-7.581643,"eighty":45.096531,"marketCap":5241464245},{"date":"2023-05-26","current":-17.042442,"twenty":-160.205418,"median":-7.581643,"eighty":45.096531,"marketCap":5604918222},{"date":"2023-06-02","current":-18.682728,"twenty":-159.773437,"median":-7.581643,"eighty":45.096531,"marketCap":6144375503},{"date":"2023-06-09","current":-18.121463,"twenty":-159.192484,"median":-7.581643,"eighty":45.096531,"marketCap":5959786673},{"date":"2023-06-16","current":-18.138866,"twenty":-156.985977,"median":-7.581643,"eighty":45.096531,"marketCap":5965510357},{"date":"2023-06-23","current":-17.925673,"twenty":-155.435521,"median":-7.578157,"eighty":45.109315,"marketCap":5895395220},{"date":"2023-06-30","current":-17.886515,"twenty":-151.740635,"median":-7.574672,"eighty":45.122099,"marketCap":5882516929},{"date":"2023-07-07","current":-18.169323,"twenty":-150.657265,"median":-7.574672,"eighty":45.122099,"marketCap":5975526805},{"date":"2023-07-14","current":-18.560903,"twenty":-150.083568,"median":-7.574672,"eighty":45.122099,"marketCap":6104309711},{"date":"2023-07-21","current":-17.821251,"twenty":-149.641501,"median":-7.574672,"eighty":45.122099,"marketCap":5861053112},{"date":"2023-07-28","current":-16.750932,"twenty":-149.090615,"median":-7.574672,"eighty":45.122099,"marketCap":5509046504},{"date":"2023-08-04","current":-17.151214,"twenty":-148.303568,"median":-7.574672,"eighty":45.122099,"marketCap":5640691252},{"date":"2023-08-11","current":-18.467972,"twenty":-148.00823,"median":-7.574672,"eighty":45.122099,"marketCap":5707249602},{"date":"2023-08-18","current":-18.147959,"twenty":-147.735407,"median":-7.574672,"eighty":45.122099,"marketCap":5608354519},{"date":"2023-08-25","current":-18.463334,"twenty":-145.579013,"median":-7.574672,"eighty":45.122099,"marketCap":5705816340},{"date":"2023-09-01","current":-18.676675,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5771746396},{"date":"2023-09-08","current":-18.727692,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5787512279},{"date":"2023-09-15","current":-20.239635,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":6254755717},{"date":"2023-09-22","current":-19.701643,"twenty":-144.797122,"median":-7.574672,"eighty":45.122099,"marketCap":6088497315},{"date":"2023-09-29","current":-21.454756,"twenty":-143.400598,"median":-7.574672,"eighty":45.122099,"marketCap":6630270382},{"date":"2023-10-06","current":-21.728389,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6714832844},{"date":"2023-10-13","current":-21.38055,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6607338188},{"date":"2023-10-20","current":-21.593891,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6673268244},{"date":"2023-10-27","current":-21.16257,"twenty":-143.300049,"median":-7.55957,"eighty":45.146419,"marketCap":6539974871},{"date":"2023-11-03","current":-15.297336,"twenty":-140.032184,"median":-7.55957,"eighty":45.146419,"marketCap":6267655075},{"date":"2023-11-10","current":-16.577399,"twenty":-22.395314,"median":-7.55957,"eighty":45.146419,"marketCap":6787665949},{"date":"2023-11-17","current":-17.008391,"twenty":-21.672735,"median":-7.55957,"eighty":45.146419,"marketCap":6964136656},{"date":"2023-11-24","current":-17.460406,"twenty":-21.484438,"median":-7.55957,"eighty":45.146419,"marketCap":7149215689},{"date":"2023-12-01","current":-17.334262,"twenty":-21.2275,"median":-7.55957,"eighty":45.146419,"marketCap":7097565726},{"date":"2023-12-08","current":-17.334262,"twenty":-20.411236,"median":-7.572349,"eighty":45.140651,"marketCap":7097565726},{"date":"2023-12-15","current":-17.456902,"twenty":-20.127399,"median":-7.572349,"eighty":45.140651,"marketCap":7147780968},{"date":"2023-12-22","current":-17.208119,"twenty":-19.907658,"median":-7.572349,"eighty":45.140651,"marketCap":7045915764},{"date":"2023-12-29","current":-17.695174,"twenty":-19.76602,"median":-7.55957,"eighty":45.146419,"marketCap":7245342009},{"date":"2024-01-05","current":-18.038565,"twenty":-19.665059,"median":-7.54679,"eighty":45.152187,"marketCap":7385944686},{"date":"2024-01-12","current":-18.763892,"twenty":-19.458602,"median":-7.54679,"eighty":45.152187,"marketCap":7682931972},{"date":"2024-01-19","current":-17.747734,"twenty":-19.2678,"median":-7.544467,"eighty":45.157955,"marketCap":7266862827},{"date":"2024-01-26","current":-18.073605,"twenty":-19.134896,"median":-7.54679,"eighty":45.152187,"marketCap":7400291898},{"date":"2024-02-02","current":-17.859862,"twenty":-19.007278,"median":-7.54679,"eighty":45.152187,"marketCap":7312773905},{"date":"2024-02-09","current":-17.512966,"twenty":-18.941814,"median":-7.54679,"eighty":45.152187,"marketCap":7170736507},{"date":"2024-02-16","current":-15.866089,"twenty":-18.881956,"median":-7.54679,"eighty":45.152187,"marketCap":6496417548},{"date":"2024-02-23","current":-17.500434,"twenty":-18.811317,"median":-7.54679,"eighty":45.152187,"marketCap":6410164032},{"date":"2024-03-01","current":-17.989873,"twenty":-18.791838,"median":-7.578157,"eighty":45.146419,"marketCap":6589438742},{"date":"2024-03-08","current":-17.774998,"twenty":-18.791838,"median":-7.603716,"eighty":45.146419,"marketCap":6510732771},{"date":"2024-03-15","current":-16.784182,"twenty":-18.791838,"median":-7.673842,"eighty":45.146419,"marketCap":6147810797},{"date":"2024-03-22","current":-17.010995,"twenty":-18.791838,"median":-7.777023,"eighty":45.146419,"marketCap":6230889321},{"date":"2024-03-28","current":-17.771018,"twenty":-18.791838,"median":-7.81825,"eighty":45.146419,"marketCap":6509275254},{"date":"2024-04-05","current":-17.042828,"twenty":-18.796083,"median":-7.904612,"eighty":45.152187,"marketCap":6242549465},{"date":"2024-04-12","current":-16.911516,"twenty":-18.796083,"median":-8.182691,"eighty":45.152187,"marketCap":6194451372},{"date":"2024-04-19","current":-16.239034,"twenty":-18.796083,"median":-8.560117,"eighty":45.152187,"marketCap":5948130835},{"date":"2024-04-26","current":-16.659633,"twenty":-18.791838,"median":-8.646128,"eighty":45.146419,"marketCap":6102190447},{"date":"2024-05-03","current":-17.157352,"twenty":-18.791838,"median":-8.845112,"eighty":45.146419,"marketCap":6284497762},{"date":"2024-05-10","current":-14.961134,"twenty":-18.791838,"median":-9.293144,"eighty":45.146419,"marketCap":5756535778},{"date":"2024-05-17","current":-14.25989,"twenty":-18.791838,"median":-9.334225,"eighty":45.146419,"marketCap":5486720952},{"date":"2024-05-24","current":-14.40393,"twenty":-18.791838,"median":-9.552464,"eighty":45.146419,"marketCap":5542142376},{"date":"2024-05-31","current":-13.854306,"twenty":-18.791838,"median":-9.739892,"eighty":45.146419,"marketCap":5330665890},{"date":"2024-06-07","current":-15.112755,"twenty":-18.791838,"median":-9.90935,"eighty":45.146419,"marketCap":5814874119},{"date":"2024-06-14","current":-15.586568,"twenty":-18.796083,"median":-9.987659,"eighty":45.152187,"marketCap":5997181434},{"date":"2024-06-21","current":-15.469062,"twenty":-18.800329,"median":-10.068299,"eighty":45.157955,"marketCap":5951969220},{"date":"2024-06-28","current":-17.902568,"twenty":-18.809069,"median":-10.099656,"eighty":45.171414,"marketCap":6888299589},{"date":"2024-07-05","current":-17.284716,"twenty":-18.809069,"median":-10.146845,"eighty":45.171414,"marketCap":6650570851},{"date":"2024-07-12","current":-17.932892,"twenty":-18.809069,"median":-10.187925,"eighty":45.171414,"marketCap":6899967258},{"date":"2024-07-15","current":-18.194437,"twenty":-18.809069,"median":-10.208466,"eighty":45.171414,"marketCap":7000600896},{"date":"2024-08-02","current":-20.490271,"twenty":-18.868176,"median":-10.389456,"eighty":45.307924,"marketCap":7484809124},{"date":"2024-08-09","current":-18.992918,"twenty":-18.884076,"median":-10.451704,"eighty":45.307924,"marketCap":6946488933},{"date":"2024-08-16","current":-18.655115,"twenty":-18.884076,"median":-10.488762,"eighty":45.307924,"marketCap":6822940561},{"date":"2024-08-23","current":-19.004911,"twenty":-18.92096,"median":-10.554325,"eighty":45.307924,"marketCap":6950875266},{"date":"2024-08-30","current":-19.948361,"twenty":-18.942377,"median":-10.636992,"eighty":45.307924,"marketCap":7295933440},{"date":"2024-09-06","current":-19.248769,"twenty":-18.979477,"median":-10.675476,"eighty":45.307924,"marketCap":7040064031},{"date":"2024-09-13","current":-17.667381,"twenty":-18.992918,"median":-10.762419,"eighty":45.307924,"marketCap":6461685590},{"date":"2024-09-20","current":-18.408188,"twenty":-18.992918,"median":-10.826557,"eighty":45.307924,"marketCap":6732629014},{"date":"2024-09-27","current":-17.701837,"twenty":-18.992918,"median":-11.068858,"eighty":45.307924,"marketCap":6474287610},{"date":"2024-10-04","current":-16.284829,"twenty":-18.992918,"median":-11.242743,"eighty":45.307924,"marketCap":5956029551},{"date":"2024-10-11","current":-16.345127,"twenty":-18.992918,"median":-12.040191,"eighty":45.307924,"marketCap":5978083085},{"date":"2024-10-18","current":-16.577706,"twenty":-18.992918,"median":-13.03948,"eighty":45.307924,"marketCap":6063146718},{"date":"2024-10-25","current":-16.698302,"twenty":-18.992918,"median":-13.446915,"eighty":45.307924,"marketCap":6107253787},{"date":"2024-10-31","current":-16.909346,"twenty":-18.992918,"median":-13.562755,"eighty":45.307924,"marketCap":6184441157},{"date":"2024-11-08","current":-16.902216,"twenty":-18.995317,"median":-13.748329,"eighty":45.31946,"marketCap":6072729658},{"date":"2024-11-15","current":-16.383322,"twenty":-18.995317,"median":-13.840323,"eighty":45.31946,"marketCap":5878515995},{"date":"2024-11-22","current":-14.935534,"twenty":-18.995317,"median":-14.176174,"eighty":45.31946,"marketCap":5359033920},{"date":"2024-11-29","current":-15.723236,"twenty":-18.995317,"median":-14.25989,"eighty":45.31946,"marketCap":5641670064},{"date":"2024-12-06","current":-16.172094,"twenty":-18.995317,"median":-14.506273,"eighty":45.31946,"marketCap":5802725297},{"date":"2024-12-13","current":-16.286509,"twenty":-18.995317,"median":-14.813304,"eighty":45.31946,"marketCap":5843778591},{"date":"2024-12-20","current":-15.661628,"twenty":-18.995317,"median":-14.935534,"eighty":45.31946,"marketCap":5619564444},{"date":"2024-12-27","current":-15.98727,"twenty":-18.995317,"median":-15.08243,"eighty":45.31946,"marketCap":5736408436},{"date":"2025-01-03","current":-15.265577,"twenty":-18.995317,"median":-15.112755,"eighty":45.31946,"marketCap":5477456886},{"date":"2025-01-10","current":-15.005943,"twenty":-18.997715,"median":-15.244128,"eighty":45.330996,"marketCap":5384297486},{"date":"2025-01-17","current":-14.205039,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5096924424},{"date":"2025-01-24","current":-15.164364,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5441140510},{"date":"2025-01-31","current":-14.662699,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5261137602},{"date":"2025-02-07","current":-14.359059,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5152188474},{"date":"2025-02-14","current":-13.35573,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4792182660},{"date":"2025-02-21","current":-11.446164,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5196558396},{"date":"2025-02-28","current":-10.979464,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4983545602},{"date":"2025-03-07","current":-12.044139,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5466798509},{"date":"2025-03-14","current":-11.522308,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5229940998},{"date":"2025-03-21","current":-11.46277,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5202916987},{"date":"2025-03-28","current":-11.109046,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5042362567},{"date":"2025-04-04","current":-9.988335,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4533675297},{"date":"2025-04-11","current":-9.354433,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4245949060},{"date":"2025-04-17","current":-9.928797,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4506651286},{"date":"2025-04-25","current":-10.356068,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4700588308},{"date":"2025-05-02","current":-11.018739,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5046935029},{"date":"2025-05-09","current":-11.380123,"twenty":-19.000114,"median":-15.297336,"eighty":45.26178,"marketCap":5212460492},{"date":"2025-05-16","current":-11.463519,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5250658676},{"date":"2025-05-23","current":-11.55734,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5293631632},{"date":"2025-05-30","current":-11.626837,"twenty":-19.000114,"median":-15.297336,"eighty":45.007986,"marketCap":5325463452},{"date":"2025-06-06","current":-12.24536,"twenty":-19.000114,"median":-15.297336,"eighty":44.117786,"marketCap":5608766648},{"date":"2025-06-13","current":-12.377404,"twenty":-19.000114,"median":-15.297336,"eighty":-6.098308,"marketCap":5669247106},{"date":"2025-06-20","current":-12.860408,"twenty":-19.002512,"median":-15.301886,"eighty":-6.769341,"marketCap":5890478253},{"date":"2025-06-27","current":-13.82294,"twenty":-19.002512,"median":-15.301886,"eighty":-6.989146,"marketCap":6331348958},{"date":"2025-07-03","current":-14.941841,"twenty":-19.002512,"median":-15.301886,"eighty":-7.017492,"marketCap":6843841257},{"date":"2025-07-11","current":-14.7264,"twenty":-19.002512,"median":-15.301886,"eighty":-7.061175,"marketCap":6745162615},{"date":"2025-07-18","current":-14.653429,"twenty":-19.002512,"median":-15.301886,"eighty":-7.105786,"marketCap":6711739204},{"date":"2025-07-25","current":-14.646479,"twenty":-19.002512,"median":-15.301886,"eighty":-7.221033,"marketCap":6708556022},{"date":"2025-08-01","current":-25.541485,"twenty":-19.026904,"median":-15.342587,"eighty":-7.288415,"marketCap":6850635022},{"date":"2025-08-08","current":-24.394555,"twenty":-19.059439,"median":-15.406519,"eighty":-7.31955,"marketCap":6543009950},{"date":"2025-08-15","current":-25.464231,"twenty":-19.208439,"median":-15.476942,"eighty":-7.439444,"marketCap":6829914162},{"date":"2025-08-22","current":-25.693023,"twenty":-19.327123,"median":-15.573133,"eighty":-7.500784,"marketCap":6891279785},{"date":"2025-08-29","current":-25.32755,"twenty":-19.462842,"median":-15.656683,"eighty":-7.572814,"marketCap":6793254179},{"date":"2025-09-05","current":-35.269594,"twenty":-19.610183,"median":-15.723236,"eighty":-7.595584,"marketCap":9459869441},{"date":"2025-09-12","current":-38.056694,"twenty":-19.731561,"median":-15.763036,"eighty":-7.642541,"marketCap":10207414305},{"date":"2025-09-19","current":-36.689886,"twenty":-19.905803,"median":-15.876073,"eighty":-7.741966,"marketCap":9840814478},{"date":"2025-09-26","current":-37.420831,"twenty":-20.021346,"median":-16.03996,"eighty":-7.801291,"marketCap":10036865690},{"date":"2025-10-03","current":-40.647687,"twenty":-20.250766,"median":-16.203648,"eighty":-7.855354,"marketCap":10902360063},{"date":"2025-10-10","current":-41.758962,"twenty":-20.936243,"median":-16.267488,"eighty":-8.057965,"marketCap":11200421661},{"date":"2025-10-17","current":-43.422902,"twenty":-21.44548,"median":-16.302057,"eighty":-8.466659,"marketCap":11646717103},{"date":"2025-10-24","current":-42.489907,"twenty":-21.627284,"median":-16.365719,"eighty":-8.619683,"marketCap":11396472873},{"date":"2025-10-31","current":-46.865674,"twenty":-22.311833,"median":-16.491552,"eighty":-8.824572,"marketCap":12013640728},{"date":"2025-11-07","current":-46.821444,"twenty":-24.565703,"median":-16.551864,"eighty":-9.220997,"marketCap":12002302521},{"date":"2025-11-14","current":-44.129685,"twenty":-25.310911,"median":-16.577552,"eighty":-9.310347,"marketCap":11312291607},{"date":"2025-11-21","current":-46.202213,"twenty":-25.459477,"median":-16.623152,"eighty":-9.406991,"marketCap":11843567616},{"date":"2025-11-28","current":-52.274467,"twenty":-25.606854,"median":-16.659586,"eighty":-9.54788,"marketCap":13400141532},{"date":"2025-12-05","current":-51.693149,"twenty":-25.977676,"median":-16.714478,"eighty":-9.709339,"marketCap":13251125091},{"date":"2025-12-12","current":-50.00606,"twenty":-36.254884,"median":-16.738094,"eighty":-9.817591,"marketCap":12818653462},{"date":"2025-12-19","current":-49.051939,"twenty":-36.458718,"median":-16.773398,"eighty":-9.930898,"marketCap":12574072128},{"date":"2025-12-26","current":-50.960181,"twenty":-37.51116,"median":-16.804783,"eighty":-9.964551,"marketCap":13063234795},{"date":"2026-01-02","current":-49.987104,"twenty":-38.080464,"median":-16.872737,"eighty":-9.994875,"marketCap":12813794230},{"date":"2026-01-09","current":-51.522544,"twenty":-40.33867,"median":-16.913584,"eighty":-10.055281,"marketCap":13207392005},{"date":"2026-01-16","current":-48.786554,"twenty":-41.579494,"median":-16.936559,"eighty":-10.101905,"marketCap":12506042883},{"date":"2026-01-23","current":-51.680511,"twenty":-42.352038,"median":-16.969214,"eighty":-10.147872,"marketCap":13247885603},{"date":"2026-01-30","current":-53.001116,"twenty":-43.304049,"median":-17.016336,"eighty":-10.177655,"marketCap":13586412084},{"date":"2026-02-06","current":-52.748369,"twenty":-43.896106,"median":-17.042828,"eighty":-10.276361,"marketCap":13521622327},{"date":"2026-02-13","current":-51.674193,"twenty":-45.89007,"median":-17.08842,"eighty":-10.365331,"marketCap":13246265859},{"date":"2026-02-20","current":-52.536693,"twenty":-46.437268,"median":-17.113581,"eighty":-10.415699,"marketCap":13467360905},{"date":"2026-02-27","current":-34.265449,"twenty":-46.808807,"median":-17.154283,"eighty":-10.419492,"marketCap":13055136075},{"date":"2026-03-06","current":-32.554417,"twenty":-46.808807,"median":-17.180856,"eighty":-10.419492,"marketCap":12415831546},{"date":"2026-03-13","current":-31.332977,"twenty":-46.808807,"median":-17.209871,"eighty":-10.419492,"marketCap":11949990075},{"date":"2026-03-20","current":-30.891179,"twenty":-46.808807,"median":-17.218631,"eighty":-10.419492,"marketCap":11781494224},{"date":"2026-03-27","current":-32.155933,"twenty":-46.808807,"median":-17.24834,"eighty":-10.419492,"marketCap":12263854896},{"date":"2026-04-02","current":-32.541423,"twenty":-46.808807,"median":-17.287579,"eighty":-10.419492,"marketCap":12410875786},{"date":"2026-04-10","current":-33.104499,"twenty":-46.808807,"median":-17.33251,"eighty":-10.419492,"marketCap":12625625400},{"date":"2026-04-17","current":-32.597731,"twenty":-46.808807,"median":-17.370954,"eighty":-10.419492,"marketCap":12432350747},{"date":"2026-04-24","current":-32.090963,"twenty":-46.808807,"median":-17.417852,"eighty":-10.419492,"marketCap":12239076094},{"date":"2026-05-01","current":-37.78562,"twenty":-46.808807,"median":-17.460406,"eighty":-10.419492,"marketCap":12355028686},{"date":"2026-05-08","current":-38.422456,"twenty":-46.808807,"median":-17.499692,"eighty":-10.425443,"marketCap":12563259507},{"date":"2026-05-15","current":-38.250612,"twenty":-46.808807,"median":-17.54086,"eighty":-10.441583,"marketCap":12507070238},{"date":"2026-05-22","current":-38.301154,"twenty":-46.808807,"median":-17.626193,"eighty":-10.45769,"marketCap":12523596493},{"date":"2026-05-29","current":-39.084564,"twenty":-46.821444,"median":-17.65446,"eighty":-10.515842,"marketCap":12779753455},{"date":"2026-06-05","current":-37.972628,"twenty":-46.808807,"median":-17.690774,"eighty":-10.584827,"marketCap":12416175832},{"date":"2026-06-12","current":-37.31052,"twenty":-46.808807,"median":-17.738974,"eighty":-10.668419,"marketCap":12199681883},{"date":"2026-06-18","current":-37.558179,"twenty":-46.808807,"median":-17.769888,"eighty":-10.69486,"marketCap":12280660536},{"date":"2026-06-26","current":-39.595044,"twenty":-46.821444,"median":-17.818766,"eighty":-10.726786,"marketCap":12946668637},{"date":"2026-07-02","current":-40.024656,"twenty":-46.821444,"median":-17.854581,"eighty":-10.726786,"marketCap":13087141809},{"date":"2026-07-10","current":-32.483705,"twenty":-46.821444,"median":-17.871767,"eighty":-10.726786,"marketCap":10621424474},{"date":"2026-07-17","current":-27.621511,"twenty":-46.821444,"median":-17.880886,"eighty":-10.979464,"marketCap":9031598685},{"date":"2026-07-24","current":-28.23813,"twenty":-46.821444,"median":-17.925673,"eighty":-11.109046,"marketCap":9233219003},{"date":"2026-07-31","current":-15.666504,"twenty":-46.83029,"median":-17.93492,"eighty":-11.257113,"marketCap":8854300676},{"date":"2026-08-07","current":-16.022293,"twenty":-46.83029,"median":-17.93492,"eighty":-11.326236,"marketCap":9055383705},{"date":"2026-08-14","current":-16.42807,"twenty":-46.83029,"median":-17.93492,"eighty":-11.457268,"marketCap":9284718070},{"date":"2026-08-21","current":-17.277849,"twenty":-46.83029,"median":-17.93492,"eighty":-11.52511,"marketCap":9764990760}],"updateTime":1787584965556},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"IONS\",pageSize:20,pageCount:1,lang_content:\"cn\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"2656329979","title":"美国研究综述-艾伯维、亚马逊、伊利姆纳","url":"https://stock-news.laohu8.com/highlight/detail?id=2656329979","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2656329979?lang=zh_cn&edition=fundamental","pubTime":"2026-08-03 15:47","pubTimestamp":1785743242,"startTime":"0","endTime":"0","summary":"美国研究综述-艾伯维、亚马逊、伊利姆纳路透8月3日-周一，华尔街证券分析师下调了包括艾伯维、亚马逊和伊利姆纳在内的多家美国上市公司评级及目标股价。股票按字母顺序排列。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260803:nL4S4400J4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IYF","MSA","RTH","LNC","OMCL","CFR","CL","MTZ","GTES","TRUH","LH","BEPC","CBNA","FHN","VCYT","TW","CHD","LAUR","BBT","BN","IXJ","WANT","FULT","ABBV","KOD","ILDR","INO","NBN","BOKF","VLY","PFG","IONS","TFNS","IR","AGIO","FTXH","CATY","IYH","ILMN","ONLN","PRM","TEM","GNOM","GNMX","ARES","AMZN","LSEG.UK","PJP","LBO","FLG"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1136465309","title":"异动解读｜Ionis Pharmaceuticals盘中上涨5.39%，报56.92美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1136465309","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1136465309?lang=zh_cn&edition=fundamental","pubTime":"2026-07-23 21:57","pubTimestamp":1784815031,"startTime":"0","endTime":"0","summary":"7月23日，Ionis Pharmaceuticals盘中上涨5.39%，报56.92美元/股，成交额2821.87万美元。Ionis Pharmaceuticals所在的生物科技行业中，个股中，艾伯维公司涨0.6%，Argenx SE涨3.77%，再生元制药公司跌1.98%，吉利德科学跌1.98%，安进跌1.22%。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。）","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1116842451","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.16%，财报前机构偏空叠加心血管管线挫折余波","url":"https://stock-news.laohu8.com/highlight/detail?id=1116842451","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1116842451?lang=zh_cn&edition=fundamental","pubTime":"2026-07-22 21:37","pubTimestamp":1784727454,"startTime":"0","endTime":"0","summary":"7月22日，Ionis Pharmaceuticals盘中下跌5.16%，报51.395美元/股，成交额3660.52万美元。消息面上，公司与阿斯利康联合开发的Eplontersen心脏转归III期试验于7月9日公布结果，在第140周未达主要终点，股价此前已单日暴跌超20%。随后RBC将目标价从100美元下调至85美元，TD Cowen从108美元下调至94美元。心血管核心管线受挫、目标价下修及财报不确定性三重因素叠加，短期内持续压制股价。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1119990036","title":"异动解读｜Ionis Pharmaceuticals盘前下跌6.35%，财报前机构偏空叠加管线挫折余波","url":"https://stock-news.laohu8.com/highlight/detail?id=1119990036","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1119990036?lang=zh_cn&edition=fundamental","pubTime":"2026-07-22 19:33","pubTimestamp":1784720018,"startTime":"0","endTime":"0","summary":"7月22日，Ionis Pharmaceuticals盘前下跌6.35%，报50.0美元/股，成交额7.72万美元。此前7月9日，公司与阿斯利康联合开发的Eplontersen心脏转归III期试验未达主要终点，股价曾单日暴跌超20%。随后RBC将目标价从100美元下调至85美元，TD Cowen从108美元下调至94美元，市场情绪持续承压。尽管公司在Diranersen及Zilganersen等管线取得积极进展，但短期内核心心血管管线受挫及财报季不确定性仍主导股价走势。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1163634673","title":"财报前瞻｜Ionis Pharmaceuticals, Inc本季度营收或小幅回落，机构观点偏谨慎","url":"https://stock-news.laohu8.com/highlight/detail?id=1163634673","media":"财报Agent","labels":["earningPreview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1163634673?lang=zh_cn&edition=fundamental","pubTime":"2026-07-22 12:19","pubTimestamp":1784693967,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals, Inc将于2026年07月29日发布最新季度财报，市场关注商业化放量与研发推进节奏对利润率的影响。Ionis Pharmaceuticals, Inc的收入结构对合作与里程碑事件高度敏感，在高基数季度后，若本季度缺乏同等量级的合作里程碑，营收回落压力将上升。近期分析师对Ionis Pharmaceuticals, Inc的短期业绩持偏谨慎态度，看空比例更高，核心依据在于合作里程碑的不确定性与费用刚性的组合使得本季度营收与利润率面临回落风险。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"财报前瞻｜Ionis Pharmaceuticals, Inc本季度营收或小幅回落，机构观点偏谨慎","news_tag":"earningPreview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1173298853","title":"Biogen公布Celia二期数据：Diranersen在早期阿尔茨海默病中展现显著临床获益及强劲Tau蛋白降低","url":"https://stock-news.laohu8.com/highlight/detail?id=1173298853","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1173298853?lang=zh_cn&edition=fundamental","pubTime":"2026-07-14 21:24","pubTimestamp":1784035453,"startTime":"0","endTime":"0","summary":"在阿尔茨海默病协会国际会议（AAIC）上，Ionis Pharmaceuticals 的合作伙伴百健（Biogen）公布了Celia二期研究数据。结果显示，在早期阿尔茨海默病患者中，候选药物Diranersen展现出具有临床意义的积极结果，并实现了Tau蛋白水平的强劲降低。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1138442146","title":"“木头姐”再度调整持仓，加码Meta、减持AMD","url":"https://stock-news.laohu8.com/highlight/detail?id=1138442146","media":"老虎资讯综合","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1138442146?lang=zh_cn&edition=fundamental","pubTime":"2026-07-10 22:38","pubTimestamp":1783694306,"startTime":"0","endTime":"0","summary":"方舟投资创始人兼首席投资官Cathie Wood周四继续调整投资组合，大举加仓 $Meta Platforms, Inc.$，同时进一步减持芯片巨头 $美国超微公司$。这也是Meta将于7月29日公布第二季度业绩前的重要布局。此外，Meta近期持续加码AI业务，不仅推出首个付费AI模型，还宣布自研AI芯片将于9月进入量产阶段。与此同时，ARK继续减持AMD，合计卖出10774股，套现约560万美元。市场分析认为，此次减持更可能是获利了结及投资组合再平衡，并不代表ARK看空AMD的基本面。","market":"us","thumbnail":"https://static.tigerbbs.com/0fb0479ff67cd3a760cdce353bcb60ed","type":0,"news_type":0,"thumbnails":["https://static.tigerbbs.com/0fb0479ff67cd3a760cdce353bcb60ed"],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOOI","AMUU","FBYY","HOOG","AMDY","META","FBY","AMDW","HOYY","METW","HOOW","HOOX","HOOY","ICRC","FBL","ROBN","CRCD","AMDL","NTRA","IONS","ROKU","HOOZ","DAMD","CRCL","METU","CCUP","HODU","AMYY","HOII","CRCO","AMDU","AMDD","CRCA","CRCG","HOOD","METD","AMD","AMDG"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"1101026949","title":"异动解读｜Ionis Pharmaceuticals盘中下跌6.04%，核心管线三期试验失败余震延续","url":"https://stock-news.laohu8.com/highlight/detail?id=1101026949","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1101026949?lang=zh_cn&edition=fundamental","pubTime":"2026-07-10 21:37","pubTimestamp":1783690641,"startTime":"0","endTime":"0","summary":"7月10日，Ionis Pharmaceuticals盘中下跌6.04%，报59.59美元/股，成交额4121.97万美元，延续前一交易日超20%的暴跌走势。消息面上，Ionis与合作伙伴阿斯利康此前宣布，其药物Eplontersen针对转甲状腺素蛋白介导的淀粉样心肌病的三期临床试验Cardio-Ttransform未能达到主要疗效终点。ATTR-CM为Ionis心脏代谢管线核心适应症，此次失败构成重大挫折。此外，TD Cowen将Ionis目标价从108美元下调至94美元，维持买入评级，进一步压制市场情绪。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650618314","title":"美国研究综述-贝莱德、彭纳特集团、威斯尔豪瑟公司","url":"https://stock-news.laohu8.com/highlight/detail?id=2650618314","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650618314?lang=zh_cn&edition=fundamental","pubTime":"2026-07-10 16:34","pubTimestamp":1783672484,"startTime":"0","endTime":"0","summary":"美国研究综述-贝莱德、彭纳特集团、威斯尔豪瑟公司路透7月10日-周五，华尔街证券分析师下调了包括贝莱德、彭纳特集团和威斯尔豪瑟公司在内的多家美国上市公司的评级和目标股价。股票条目按字母顺序排列。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260710:nL4S43C0KE:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACHC","FTXH","PNTG","VDE","CVS","HONA","NULC","OC","XLP","TYLG","SEIC","IONS","SF","TROW","FTXN","PJT","XLE","BTSG","FENY","FHLC","BLK","NSC","RMD","AVXX","RTH","XHB","AVAV","FTXG","HLNE","HLI","PPH","PEP","KO","RXL","WY","CHE","CVX","WEEI","EVR","RJF","SNPE","PWP","OGIG","DRLL","MSFT","MRK","LAZ","XLK","ROM","XLV"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1118873423","title":"异动解读｜Ionis Pharmaceuticals盘中下跌20.03%，核心管线Eplontersen三期心脏试验未达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1118873423","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1118873423?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 22:46","pubTimestamp":1783608396,"startTime":"0","endTime":"0","summary":"7月9日，Ionis Pharmaceuticals盘中下跌20.03%，报67.55美元/股，成交额5.38亿美元。消息面上，Ionis与合作伙伴阿斯利康宣布，其药物Eplontersen针对转甲状腺素蛋白介导的淀粉样心肌病的三期临床试验Cardio-Ttransform未能达到主要疗效终点。ATTR-CM是Ionis心脏代谢管线的核心适应症之一，此次试验失败对公司该领域布局构成重大挫折。Ionis与阿斯利康计划继续分析完整数据，并将于8月欧洲心脏病学会大会上公布详细结果。受同一消息拖累，阿斯利康盘前亦跌超8%。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650929828","title":"联合开发心脏药物III期试验未达主要终点，阿斯利康与Ionis股价暴跌","url":"https://stock-news.laohu8.com/highlight/detail?id=2650929828","media":"智通财经","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650929828?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 19:57","pubTimestamp":1783598269,"startTime":"0","endTime":"0","summary":"7月9日，阿斯利康与IONS联合开发的一款实验性心脏病药物在后期临床试验中未能达到主要疗效终点，Ionis股价盘前下跌超20%，阿斯利康盘前跌超8%。","market":"us","thumbnail":"https://community-static.tradeup.com/news/56ac818c9a46212bd08488d4935a4dad","type":0,"news_type":0,"thumbnails":["https://community-static.tradeup.com/news/56ac818c9a46212bd08488d4935a4dad"],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://www.zhitongcaijing.com/content/detail/1465485.html","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"stock_zhitongcaijing","symbols":["BK4007","III","LU0889565916.HKD","IONS","BK4134","LU2417539215.USD","LU0109394709.USD","LU2456880835.USD","BK4139","LU2462157665.USD","LU2237443465.HKD","LU1267930573.SGD","AZN","LU0310800379.SGD","LU2236285917.USD","LU2237443622.USD","LU0320765992.SGD","LU0128525929.USD","BK4585","BK4588","LU0289739699.SGD","LU0708994859.HKD","LU2468319806.SGD","BK4568","LU1829250122.USD","LU2237443549.SGD","LU2237443978.SGD","LU2237443382.USD","LU2237443895.HKD","LU0058720904.USD","IE00B3T34201.USD","LU0432979614.USD","LU0029864427.USD","LU2089984988.USD","AZNH"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2650492956","title":"BUZZ——美国股市动态-Levi、Ionis Pharmaceuticals、Gloo Holdings","url":"https://stock-news.laohu8.com/highlight/detail?id=2650492956","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650492956?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 19:37","pubTimestamp":1783597073,"startTime":"0","endTime":"0","summary":"BUZZ——美国股市动态-Levi、Ionis Pharmaceuticals、Gloo Holdings工作区中用于查询单只股票行情的搜索字符串：STXBZ《Day Ahead》通讯：https://refini.tv/3LI4BU7《晨间新闻简报》：https://refini.tv/3dKUyB8路透7月9日-周四，美国股指期货小幅走高，此前美国对伊朗发动新一轮空袭，重新点燃了地缘政治担忧，","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4T43B0ZT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["FCX","LU0969580561.USD","LU0661504455.SGD","HEAL","LU0823416689.USD","LU2357627491.SGD","LU2237443895.HKD","LU1023059063.AUD","FTXG","IONS","BK4121","LU1430597077.USD","LU0029864427.USD","LU0171293334.USD","LU0784384876.USD","FTRE","LU0310800379.SGD","LU0511384066.AUD","PEP","SCCO","LU0792757196.USD","AZN.UK","LU2114397693.USD","EART","LU1815336091.USD","LU2089984988.USD","03165","LU0648001328.SGD","GLSI","COPA","COPX","IE0000B7K699.USD","EKG","GLOO","ICLR","COPP","IQV","LEVI","LU1201861249.SGD","LU2244417387.USD","PICK","LU0654597011.USD","LU1496350171.SGD","SETM","FCXG","LU1201861165.SGD","CRL","BHP.AU","ICOP","GMET"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650929827","title":"联合开发心脏药物III期试验未达主要终点 阿斯利康(AZN.US)与Ionis(IONS.US)股价暴跌","url":"https://stock-news.laohu8.com/highlight/detail?id=2650929827","media":"智通财经","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650929827?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 19:29","pubTimestamp":1783596558,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.zhitongcaijing.com/immediately.html?type=usstock","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"live_zhitongcaijing","symbols":["BK4588","BK4568","LU0128525929.USD","BK4134","IE00B3T34201.USD","LU2237443978.SGD","LU2462157665.USD","LU2468319806.SGD","LU0310800379.SGD","LU2417539215.USD","LU1267930573.SGD","AZN","LU0058720904.USD","LU0889565916.HKD","LU2237443895.HKD","LU0289739699.SGD","LU2236285917.USD","LU2456880835.USD","BK4139","III","LU2237443622.USD","LU0708994859.HKD","LU2089984988.USD","LU2237443465.HKD","LU2237443549.SGD","LU1829250122.USD","LU0029864427.USD","IONS","LU0109394709.USD","AZNH","LU2237443382.USD","LU0432979614.USD","LU0320765992.SGD","BK4007","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650268739","title":"受中东局势持续紧张影响，伦敦富时100指数走低，阿斯利康拖累大盘","url":"https://stock-news.laohu8.com/highlight/detail?id=2650268739","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650268739?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 19:02","pubTimestamp":1783594923,"startTime":"0","endTime":"0","summary":"截至GMT10:45，蓝筹股富时100指数.FTSE下跌0.6%，报10,417.63点；而中盘股富时250指数.FTMC则上涨0.1%。制药股.FTNMX201030表现最差，下跌6.2%，其中阿斯利康AZN.L领跌，跌幅达9.2%。贵金属矿商.FTNMX551030上涨2.6%，跟随金价走高——美元走软提升了黄金的吸引力，与此同时，投资者继续密切关注中东局势，以寻找有关通胀和利率前景的线索。GOL/PlaytechPTEC.L领涨中盘股指数，涨幅达17.7%。ComputacenterCCC.L也是该基准指数中表现最佳的个股之一，涨幅超过7%。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4S43B0XY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2114397693.USD","LU2125909247.SGD","LU0171276677.USD","IE0002141913.USD","LU1119994496.HKD","LU0557290698.USD","LU0960981461.USD","LU2539964713.USD","CCC.UK","LU0859254822.USD","LU1267930227.SGD","LU0792757196.USD","LU0972486137.USD","LU1291159041.SGD","PTEC.UK","IONS","LU0128525689.USD","LU0920840948.USD","LU2237443382.USD","IE0009355771.USD","LU0203347892.USD","LU1267930813.SGD","LU0553294199.USD","LU0784385840.USD","03165","LU0784385170.HKD","LU1989772923.USD","LU0823399737.USD","BK5094","LU1267930573.SGD","LU2089984988.USD","LU1057294990.SGD","LU1084165304.USD","LU2125909593.SGD","LU2237443978.SGD","LU2133065610.SGD","LU0211326755.USD","AZN.UK","LU1196032939.SGD","LU0058720904.USD","LU2112291526.USD","LU1051770623.HKD","LU1983299246.USD","LU2355687059.USD","BK4139","LU0047473722.EUR","LU0997586515.USD","BK5077","LU1814569148.SGD","LU0827474353.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1107257650","title":"与阿斯利康合作研发药物三期心脏病试验失败，Ionis Pharmaceuticals盘前股价大跌13.8%","url":"https://stock-news.laohu8.com/highlight/detail?id=1107257650","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1107257650?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 16:29","pubTimestamp":1783585755,"startTime":"0","endTime":"0","summary":"因与阿斯利康制药合作开发的一款药物在晚期心脏病临床试验中未能达到主要终点，Ionis Pharmaceuticals, Inc的股价在盘前交易时段应声下挫13.8%。此次试验挫折对市场关于该药物前景的预期造成了显著打击，导致投资者迅速抛售股票。股价的剧烈波动反映出市场对生物制药公司研发管线进展的高度敏感性，尤其是在关键后期试验阶段的结果公布之时。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1064927863.SGD","LU0128525689.USD","LU0211327993.USD","LU2112291526.USD","LU2114397693.USD","LU2293690249.USD","LU0545039389.USD","IE00BKPKM643.USD","LU0128525929.USD","LU0972486137.USD","LU1003077747.HKD","LU2108987350.USD","LU0887340254.USD","LU0784383803.USD","LU0949170426.SGD","LU0857590862.USD","LU2237443622.USD","LU0708994859.HKD","LU1046234339.USD","LU1880407132.USD","LU0158827948.USD","LU0920783379.SGD","LU0390134368.USD","LU1829250122.USD","LU0827474353.SGD","LU0640478417.SGD","LU1057294990.SGD","LU2237443465.HKD","LU1003076772.USD","LU2089283258.USD","LU0997586432.USD","LU1019634622.SGD","LU0949170772.SGD","LU0976567544.SGD","LU0784385840.USD","LU2324357040.USD","LU0171293334.USD","LU0792757196.USD","LU2091194634.USD","LU0553294199.USD","LU0058720904.USD","LU1291159041.SGD","LU1078025761.USD","LU1267930227.SGD","LU1989772923.USD","LU0963555726.SGD","LU0211328371.USD","LU0575583348.USD","LU0557290698.USD","LU0997586515.USD","BK4139","LU2125909247.SGD","LU0077335932.USD","IE00BJJMRZ35.SGD","LU1989771016.USD","LU0310799852.SGD","LU0499090636.EUR","LU1061106388.HKD","LU2125909593.SGD","LU2237443549.SGD","LU0757432116.USD","LU0047473722.SGD","LU1084165304.USD","LU0211326839.USD","LU0526926950.USD","LU0203345920.USD","LU1923622614.USD","LU2355687059.USD","LU2237443382.USD","SGXZ57979304.SGD","LU1196032939.SGD","LU2357627491.SGD","IE00BFTCPJ56.SGD","LU1481600234.SGD","LU0171276677.USD","LU0823399737.USD","LU2279689827.SGD","LU0784385170.HKD","LU0859254822.USD","IE00BJT1NW94.SGD","LU1019632923.USD","LU0114720955.EUR","LU1267930573.SGD","LU1267930490.SGD","SG9999001176.USD","LU0661504455.SGD","LU1153584641.USD","LU1170363599.USD","LU0345777147.USD","LU0738911758.USD","LU0784384876.USD","AZN.UK","IE00B2B36J28.USD","LU0957799991.USD","IONS","LU0310800379.SGD","LU2023251221.USD","LU0211326755.USD","LU1880407215.USD","IE0009355771.USD","LU0052756011.USD","LU1273509221.SGD","LU2237443978.SGD","LU1983299246.USD","LU2133065610.SGD","LU0345777659.USD","LU1323610961.USD","LU1496350171.SGD","LU1814569148.SGD","IE00B3T34201.USD","LU0823416689.USD","LU1267930813.SGD","SG9999001176.SGD","LU1104425308.USD","LU0432979614.USD","LU2293690082.USD","LU1119994496.HKD","LU1355424745.HKD","LU0496365809.HKD","LU0889565080.SGD","LU0964806797.USD","IE00B4R5TH58.HKD","LU0203347892.USD","IE0002141913.USD","LU2468319806.SGD","LU1496350502.SGD","LU0266013472.USD","LU1481599808.USD","LU2089984988.USD","LU2433249047.HKD","LU1487256676.USD","LU0122379950.USD","LU0889566641.SGD","LU1301847155.USD","LU1261432733.SGD","SG9999013999.USD","LU2237443895.HKD","LU2539964713.USD","LU1015430645.USD","03165","LU1153585028.USD","IE0034235188.USD","LU0969580561.USD","LU0960981461.USD","LU1051770623.HKD","LU1023059063.AUD","BK5011","LU0029864427.USD","LU0882574055.USD","LU0920840948.USD","LU1989772840.SGD","LU2089284900.SGD","LU0310800965.SGD","LU0289739699.SGD","LU0047473722.EUR","LU0011850046.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1142104638","title":"异动解读｜Ionis Pharmaceuticals盘前下跌14.75%，核心管线三期试验未达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1142104638","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1142104638?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 16:20","pubTimestamp":1783585239,"startTime":"0","endTime":"0","summary":"7月9日，Ionis Pharmaceuticals盘前下跌14.75%，报74.68美元/股，成交额8.62万美元。消息面上，Ionis与合作伙伴阿斯利康宣布，其药物Eplontersen针对转甲状腺素蛋白介导的淀粉样心肌病的三期临床试验Cardio-Ttransform未能达到主要疗效终点。Ionis与阿斯利康计划继续分析完整数据，并于8月欧洲心脏病学会大会上公布结果。Ionis是一家商业阶段生物技术公司，拥有七种已上市药物，管线覆盖神经病学、心脏代谢疾病等领域，此次ATTR-CM试验失败对其心脏代谢管线构成重大挫折。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650941777","title":"阿斯利康因心脏病药物晚期临床试验失败，成为富时100指数中跌幅最大的个股","url":"https://stock-news.laohu8.com/highlight/detail?id=2650941777","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650941777?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 15:26","pubTimestamp":1783581986,"startTime":"0","endTime":"0","summary":"BUZZ-阿斯利康因心脏病药物晚期临床试验失败，成为富时100指数中跌幅最大的个股7月9日-** 阿斯利康（AZN.L）股价一度暴跌9.6%至12,874便士；有望创下自2017年以来最惨淡的一天** AZN成为富时100指数.FTSE中跌幅最大的个股，该指数下跌0.4%** 该公司表示，其与Ionis（IONS.O）合作研发的神经疾病药物Wainua，在晚期临床试验中 (link) 未能达到降低心血管死亡率及心血管疾病复发率的主要目标** 今年以来，AZN股价下跌6%","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4S43B0KZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2237443895.HKD","LU2433249047.HKD","LU1003077747.HKD","LU2357627491.SGD","IE00BFTCPJ56.SGD","LU0203347892.USD","LU1261432733.SGD","LU0553294199.USD","LU0047473722.SGD","LU0857590862.USD","LU0976567544.SGD","LU0859254822.USD","LU0432979614.USD","LU1119994496.HKD","LU1496350502.SGD","LU1267930227.SGD","LU0266013472.USD","LU1003076772.USD","AZN.UK","LU1481600234.SGD","LU0128525929.USD","LU1989772923.USD","LU0887340254.USD","LU2125909593.SGD","IE0002141913.USD","LU1323610961.USD","IE00B2B36J28.USD","LU0058720904.USD","LU1023059063.AUD","LU1061106388.HKD","LU2023251221.USD","03165","LU2539964713.USD","LU2237443382.USD","LU0345777147.USD","LU0575583348.USD","IONS","LU1983299246.USD","LU0114720955.EUR","LU0203345920.USD","LU1481599808.USD","LU1170363599.USD","LU1291159041.SGD","LU0949170772.SGD","LU0557290698.USD","IE00BKPKM643.USD","LU1267930813.SGD","LU1019634622.SGD","LU0128525689.USD","LU0122379950.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650462469","title":"阿斯利康与Ionis合作研发的药物在晚期心脏病临床试验中未能达到主要目标","url":"https://stock-news.laohu8.com/highlight/detail?id=2650462469","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650462469?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 14:11","pubTimestamp":1783577471,"startTime":"0","endTime":"0","summary":"阿斯利康与Ionis合作研发的药物在晚期心脏病临床试验中未能达到主要目标路透7月9日-阿斯利康AZN.L周四表示，其与IonisIONS.O合作研发的药物Wainua在后期临床试验中未能达到降低心血管死亡率和心血管疾病复发率这一主要目标。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4S43B0FZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0011850046.USD","LU1196032939.SGD","LU1355424745.HKD","BK5011","LU1301847155.USD","IE00B4R5TH58.HKD","LU0047473722.EUR","LU1989772923.USD","IE0009355771.USD","LU2539964713.USD","LU0211326755.USD","LU0661504455.SGD","LU2133065610.SGD","LU0058720904.USD","LU2355687059.USD","LU2112291526.USD","LU2108987350.USD","LU0963555726.SGD","LU1267930813.SGD","LU2089283258.USD","LU2114397693.USD","03165","LU1078025761.USD","LU1880407132.USD","IONS","LU1880407215.USD","LU0171293334.USD","LU1019632923.USD","LU0997586432.USD","LU0077335932.USD","LU0345777659.USD","LU1496350502.SGD","LU0203347892.USD","AZN.UK","LU0047473722.SGD","LU0823416689.USD","LU0827474353.SGD","LU1057294990.SGD","LU0029864427.USD","LU0345777147.USD","IE0002141913.USD","LU0211326839.USD","LU0390134368.USD","LU0122379950.USD","LU2089284900.SGD","LU0310799852.SGD","LU0997586515.USD","LU0889566641.SGD","LU0920840948.USD","LU0792757196.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1123213240","title":"Ionis制药Eplontersen三期心脏转归试验至第140周未达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1123213240","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1123213240?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 14:02","pubTimestamp":1783576945,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals, Inc宣布，其针对药物Eplontersen开展的三期心脏转归临床试验“Cardio-Ttransform”，在截至第140周的分析中未能达到主要研究终点。\n该试验旨在评估Eplontersen在特定患者群体中的心血管获益。尽管未能达到预设的主要终点，但公司表示，试验过程中收集到的全面数据正在进行深入分析，以评估药物的整体获益风险特征，并为未来的开发决策提供依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1138721848","title":"Eplontersen治疗转甲状腺素蛋白介导淀粉样心肌病成人患者的Cardio-Ttransform三期试验最新进展","url":"https://stock-news.laohu8.com/highlight/detail?id=1138721848","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1138721848?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 14:00","pubTimestamp":1783576824,"startTime":"0","endTime":"0","summary":"针对Eplontersen用于治疗转甲状腺素蛋白介导的淀粉样心肌病成人患者的Cardio-Ttransform三期临床试验，现已发布最新动态。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":1,"totalSize":46,"code":"91000000","status":"200"}]}}