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Ionis Pharmaceuticals, Inc

59.74

+0.98001.67%

盘后：60.650.9130+1.53%19:58 EDT

成交量：272.39万

成交额：1.63亿

市值：99.28亿

市盈率：-17.17

高：60.92

开：59.64

低：59.06

收：58.76

52周最高：86.74

52周最低：41.71

股本：1.66亿

流通股本：1.62亿

量比：1.15

换手率：1.68%

股息：- -

股息率：- -

每股收益(TTM):-3.4800

每股收益(LYR):-2.3812

净资产收益率：-105.50%

总资产收益率：-12.42%

市净率：22.58

市盈率(LYR):-25.09

数据加载中...

总览公司新闻资讯公告

美国研究综述-艾伯维、亚马逊、伊利姆纳

异动解读｜Ionis Pharmaceuticals盘中上涨5.39%，报56.92美元

异动解读｜Ionis Pharmaceuticals盘中下跌5.16%，财报前机构偏空叠加心血管管线挫折余波

异动解读｜Ionis Pharmaceuticals盘前下跌6.35%，财报前机构偏空叠加管线挫折余波

财报前瞻｜Ionis Pharmaceuticals, Inc本季度营收或小幅回落，机构观点偏谨慎

Biogen公布Celia二期数据：Diranersen在早期阿尔茨海默病中展现显著临床获益及强劲Tau蛋白降低

“木头姐”再度调整持仓，加码Meta、减持AMD

老虎资讯综合

异动解读｜Ionis Pharmaceuticals盘中下跌6.04%，核心管线三期试验失败余震延续

美国研究综述-贝莱德、彭纳特集团、威斯尔豪瑟公司

异动解读｜Ionis Pharmaceuticals盘中下跌20.03%，核心管线Eplontersen三期心脏试验未达主要终点

联合开发心脏药物III期试验未达主要终点，阿斯利康与Ionis股价暴跌

BUZZ——美国股市动态-Levi、Ionis Pharmaceuticals、Gloo Holdings

联合开发心脏药物III期试验未达主要终点阿斯利康(AZN.US)与Ionis(IONS.US)股价暴跌

受中东局势持续紧张影响，伦敦富时100指数走低，阿斯利康拖累大盘

与阿斯利康合作研发药物三期心脏病试验失败，Ionis Pharmaceuticals盘前股价大跌13.8%

异动解读｜Ionis Pharmaceuticals盘前下跌14.75%，核心管线三期试验未达主要终点

阿斯利康因心脏病药物晚期临床试验失败，成为富时100指数中跌幅最大的个股

阿斯利康与Ionis合作研发的药物在晚期心脏病临床试验中未能达到主要目标

Ionis制药Eplontersen三期心脏转归试验至第140周未达主要终点

Eplontersen治疗转甲状腺素蛋白介导淀粉样心肌病成人患者的Cardio-Ttransform三期试验最新进展

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Pharmaceuticals盘中下跌5.16%，报51.395美元/股，成交额3660.52万美元。消息面上，公司与阿斯利康联合开发的Eplontersen心脏转归III期试验于7月9日公布结果，在第140周未达主要终点，股价此前已单日暴跌超20%。随后RBC将目标价从100美元下调至85美元，TD Cowen从108美元下调至94美元。心血管核心管线受挫、目标价下修及财报不确定性三重因素叠加，短期内持续压制股价。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1119990036","title":"异动解读｜Ionis Pharmaceuticals盘前下跌6.35%，财报前机构偏空叠加管线挫折余波","url":"https://stock-news.laohu8.com/highlight/detail?id=1119990036","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1119990036?lang=zh_cn&edition=fundamental","pubTime":"2026-07-22 19:33","pubTimestamp":1784720018,"startTime":"0","endTime":"0","summary":"7月22日，Ionis Pharmaceuticals盘前下跌6.35%，报50.0美元/股，成交额7.72万美元。此前7月9日，公司与阿斯利康联合开发的Eplontersen心脏转归III期试验未达主要终点，股价曾单日暴跌超20%。随后RBC将目标价从100美元下调至85美元，TD Cowen从108美元下调至94美元，市场情绪持续承压。尽管公司在Diranersen及Zilganersen等管线取得积极进展，但短期内核心心血管管线受挫及财报季不确定性仍主导股价走势。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1163634673","title":"财报前瞻｜Ionis Pharmaceuticals, Inc本季度营收或小幅回落，机构观点偏谨慎","url":"https://stock-news.laohu8.com/highlight/detail?id=1163634673","media":"财报Agent","labels":["earningPreview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1163634673?lang=zh_cn&edition=fundamental","pubTime":"2026-07-22 12:19","pubTimestamp":1784693967,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals, Inc将于2026年07月29日发布最新季度财报，市场关注商业化放量与研发推进节奏对利润率的影响。Ionis Pharmaceuticals, Inc的收入结构对合作与里程碑事件高度敏感，在高基数季度后，若本季度缺乏同等量级的合作里程碑，营收回落压力将上升。近期分析师对Ionis Pharmaceuticals, Inc的短期业绩持偏谨慎态度，看空比例更高，核心依据在于合作里程碑的不确定性与费用刚性的组合使得本季度营收与利润率面临回落风险。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"财报前瞻｜Ionis Pharmaceuticals, Inc本季度营收或小幅回落，机构观点偏谨慎","news_tag":"earningPreview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1173298853","title":"Biogen公布Celia二期数据：Diranersen在早期阿尔茨海默病中展现显著临床获益及强劲Tau蛋白降低","url":"https://stock-news.laohu8.com/highlight/detail?id=1173298853","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1173298853?lang=zh_cn&edition=fundamental","pubTime":"2026-07-14 21:24","pubTimestamp":1784035453,"startTime":"0","endTime":"0","summary":"在阿尔茨海默病协会国际会议（AAIC）上，Ionis Pharmaceuticals 的合作伙伴百健（Biogen）公布了Celia二期研究数据。结果显示，在早期阿尔茨海默病患者中，候选药物Diranersen展现出具有临床意义的积极结果，并实现了Tau蛋白水平的强劲降低。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1138442146","title":"“木头姐”再度调整持仓，加码Meta、减持AMD","url":"https://stock-news.laohu8.com/highlight/detail?id=1138442146","media":"老虎资讯综合","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1138442146?lang=zh_cn&edition=fundamental","pubTime":"2026-07-10 22:38","pubTimestamp":1783694306,"startTime":"0","endTime":"0","summary":"方舟投资创始人兼首席投资官Cathie Wood周四继续调整投资组合，大举加仓 $Meta Platforms, Inc.$，同时进一步减持芯片巨头 $美国超微公司$。这也是Meta将于7月29日公布第二季度业绩前的重要布局。此外，Meta近期持续加码AI业务，不仅推出首个付费AI模型，还宣布自研AI芯片将于9月进入量产阶段。与此同时，ARK继续减持AMD，合计卖出10774股，套现约560万美元。市场分析认为，此次减持更可能是获利了结及投资组合再平衡，并不代表ARK看空AMD的基本面。","market":"us","thumbnail":"https://static.tigerbbs.com/0fb0479ff67cd3a760cdce353bcb60ed","type":0,"news_type":0,"thumbnails":["https://static.tigerbbs.com/0fb0479ff67cd3a760cdce353bcb60ed"],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOOI","AMUU","FBYY","HOOG","AMDY","META","FBY","AMDW","HOYY","METW","HOOW","HOOX","HOOY","ICRC","FBL","ROBN","CRCD","AMDL","NTRA","IONS","ROKU","HOOZ","DAMD","CRCL","METU","CCUP","HODU","AMYY","HOII","CRCO","AMDU","AMDD","CRCA","CRCG","HOOD","METD","AMD","AMDG"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"1101026949","title":"异动解读｜Ionis Pharmaceuticals盘中下跌6.04%，核心管线三期试验失败余震延续","url":"https://stock-news.laohu8.com/highlight/detail?id=1101026949","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1101026949?lang=zh_cn&edition=fundamental","pubTime":"2026-07-10 21:37","pubTimestamp":1783690641,"startTime":"0","endTime":"0","summary":"7月10日，Ionis Pharmaceuticals盘中下跌6.04%，报59.59美元/股，成交额4121.97万美元，延续前一交易日超20%的暴跌走势。消息面上，Ionis与合作伙伴阿斯利康此前宣布，其药物Eplontersen针对转甲状腺素蛋白介导的淀粉样心肌病的三期临床试验Cardio-Ttransform未能达到主要疗效终点。ATTR-CM为Ionis心脏代谢管线核心适应症，此次失败构成重大挫折。此外，TD Cowen将Ionis目标价从108美元下调至94美元，维持买入评级，进一步压制市场情绪。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650618314","title":"美国研究综述-贝莱德、彭纳特集团、威斯尔豪瑟公司","url":"https://stock-news.laohu8.com/highlight/detail?id=2650618314","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650618314?lang=zh_cn&edition=fundamental","pubTime":"2026-07-10 16:34","pubTimestamp":1783672484,"startTime":"0","endTime":"0","summary":"美国研究综述-贝莱德、彭纳特集团、威斯尔豪瑟公司路透7月10日-周五，华尔街证券分析师下调了包括贝莱德、彭纳特集团和威斯尔豪瑟公司在内的多家美国上市公司的评级和目标股价。股票条目按字母顺序排列。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260710:nL4S43C0KE:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACHC","FTXH","PNTG","VDE","CVS","HONA","NULC","OC","XLP","TYLG","SEIC","IONS","SF","TROW","FTXN","PJT","XLE","BTSG","FENY","FHLC","BLK","NSC","RMD","AVXX","RTH","XHB","AVAV","FTXG","HLNE","HLI","PPH","PEP","KO","RXL","WY","CHE","CVX","WEEI","EVR","RJF","SNPE","PWP","OGIG","DRLL","MSFT","MRK","LAZ","XLK","ROM","XLV"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1118873423","title":"异动解读｜Ionis Pharmaceuticals盘中下跌20.03%，核心管线Eplontersen三期心脏试验未达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1118873423","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1118873423?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 22:46","pubTimestamp":1783608396,"startTime":"0","endTime":"0","summary":"7月9日，Ionis Pharmaceuticals盘中下跌20.03%，报67.55美元/股，成交额5.38亿美元。消息面上，Ionis与合作伙伴阿斯利康宣布，其药物Eplontersen针对转甲状腺素蛋白介导的淀粉样心肌病的三期临床试验Cardio-Ttransform未能达到主要疗效终点。ATTR-CM是Ionis心脏代谢管线的核心适应症之一，此次试验失败对公司该领域布局构成重大挫折。Ionis与阿斯利康计划继续分析完整数据，并将于8月欧洲心脏病学会大会上公布详细结果。受同一消息拖累，阿斯利康盘前亦跌超8%。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650929828","title":"联合开发心脏药物III期试验未达主要终点，阿斯利康与Ionis股价暴跌","url":"https://stock-news.laohu8.com/highlight/detail?id=2650929828","media":"智通财经","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650929828?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 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阿斯利康(AZN.US)与Ionis(IONS.US)股价暴跌","url":"https://stock-news.laohu8.com/highlight/detail?id=2650929827","media":"智通财经","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650929827?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 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19:02","pubTimestamp":1783594923,"startTime":"0","endTime":"0","summary":"截至GMT10:45，蓝筹股富时100指数.FTSE下跌0.6%，报10,417.63点；而中盘股富时250指数.FTMC则上涨0.1%。制药股.FTNMX201030表现最差，下跌6.2%，其中阿斯利康AZN.L领跌，跌幅达9.2%。贵金属矿商.FTNMX551030上涨2.6%，跟随金价走高——美元走软提升了黄金的吸引力，与此同时，投资者继续密切关注中东局势，以寻找有关通胀和利率前景的线索。GOL/PlaytechPTEC.L领涨中盘股指数，涨幅达17.7%。ComputacenterCCC.L也是该基准指数中表现最佳的个股之一，涨幅超过7%。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4S43B0XY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK5094","LU0792757196.USD","IE0009355771.USD","LU0171276677.USD","IONS","LU2125909247.SGD","LU2539964713.USD","BK5077","LU0859254822.USD","LU1267930227.SGD","CCC.UK","LU0784385170.HKD","LU1051770623.HKD","LU1291159041.SGD","BK4139","LU2125909593.SGD","LU0203347892.USD","LU0960981461.USD","LU0997586515.USD","LU2133065610.SGD","LU0058720904.USD","LU2112291526.USD","LU0211326755.USD","03165","LU1119994496.HKD","IE0002141913.USD","LU2355687059.USD","LU0553294199.USD","LU0047473722.EUR","LU0827474353.SGD","LU0128525689.USD","LU0920840948.USD","LU0784385840.USD","LU2237443978.SGD","LU0972486137.USD","LU1983299246.USD","LU0557290698.USD","LU2089984988.USD","PTEC.UK","AZN.UK","LU2237443382.USD","LU1267930573.SGD","LU1084165304.USD","LU1057294990.SGD","LU2114397693.USD","LU1267930813.SGD","LU1196032939.SGD","LU1814569148.SGD","LU1989772923.USD","LU0823399737.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1107257650","title":"与阿斯利康合作研发药物三期心脏病试验失败，Ionis Pharmaceuticals盘前股价大跌13.8%","url":"https://stock-news.laohu8.com/highlight/detail?id=1107257650","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1107257650?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 16:29","pubTimestamp":1783585755,"startTime":"0","endTime":"0","summary":"因与阿斯利康制药合作开发的一款药物在晚期心脏病临床试验中未能达到主要终点，Ionis Pharmaceuticals, Inc的股价在盘前交易时段应声下挫13.8%。此次试验挫折对市场关于该药物前景的预期造成了显著打击，导致投资者迅速抛售股票。股价的剧烈波动反映出市场对生物制药公司研发管线进展的高度敏感性，尤其是在关键后期试验阶段的结果公布之时。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2468319806.SGD","IE00BJT1NW94.SGD","LU1057294990.SGD","SG9999001176.SGD","LU0545039389.USD","LU2237443978.SGD","LU0345777659.USD","IE0002141913.USD","LU0310800965.SGD","LU2125909593.SGD","LU0203347892.USD","LU0960981461.USD","IE00B4R5TH58.HKD","LU2091194634.USD","IE00BFTCPJ56.SGD","LU0211328371.USD","LU0310799852.SGD","LU0792757196.USD","LU0757432116.USD","LU1003077747.HKD","LU1196032939.SGD","LU1880407215.USD","LU1323610961.USD","LU2539964713.USD","LU0266013472.USD","BK5011","LU0738911758.USD","LU1023059063.AUD","LU0047473722.EUR","LU0128525689.USD","LU1153585028.USD","LU2023251221.USD","SG9999001176.USD","LU0784385170.HKD","LU0964806797.USD","LU1104425308.USD","LU0887340254.USD","LU2125909247.SGD","LU0997586515.USD","LU1481599808.USD","LU1989772840.SGD","LU0122379950.USD","LU1301847155.USD","LU1084165304.USD","LU2237443895.HKD","LU0784385840.USD","LU1119994496.HKD","LU0211326755.USD","LU0920783379.SGD","LU1355424745.HKD","IE0034235188.USD","LU1291159041.SGD","LU2089984988.USD","IE0009355771.USD","LU0432979614.USD","LU0882574055.USD","LU0171293334.USD","LU0345777147.USD","LU0963555726.SGD","LU0553294199.USD","IE00BKPKM643.USD","LU0997586432.USD","LU1267930573.SGD","LU0058720904.USD","LU1267930490.SGD","LU0640478417.SGD","LU2293690082.USD","BK4139","LU2237443382.USD","LU2324357040.USD","LU0823416689.USD","LU2293690249.USD","LU1046234339.USD","LU2355687059.USD","LU1989772923.USD","LU1064927863.SGD","LU0920840948.USD","03165","LU0969580561.USD","LU0114720955.EUR","LU0526926950.USD","SGXZ57979304.SGD","LU1078025761.USD","LU0575583348.USD","LU1481600234.SGD","IE00BJJMRZ35.SGD","IE00B2B36J28.USD","LU0390134368.USD","LU0499090636.EUR","LU1019634622.SGD","LU1267930227.SGD","LU0496365809.HKD","LU0171276677.USD","SG9999013999.USD","LU1983299246.USD","LU0029864427.USD","LU1880407132.USD","IONS","LU1061106388.HKD","LU2133065610.SGD","LU0077335932.USD","LU1496350171.SGD","LU0557290698.USD","LU0972486137.USD","LU2089283258.USD","LU0857590862.USD","LU0211327993.USD","LU2237443622.USD","LU0784383803.USD","LU0011850046.USD","LU0211326839.USD","LU0957799991.USD","LU1814569148.SGD","LU0289739699.SGD","LU0889565080.SGD","LU1487256676.USD","LU1153584641.USD","LU1003076772.USD","LU2108987350.USD","LU2114397693.USD","LU1261432733.SGD","LU2237443465.HKD","LU2089284900.SGD","LU0661504455.SGD","LU0949170426.SGD","LU0158827948.USD","LU1019632923.USD","LU1015430645.USD","LU2279689827.SGD","AZN.UK","LU0889566641.SGD","LU2112291526.USD","LU1989771016.USD","LU2237443549.SGD","LU1267930813.SGD","LU0823399737.USD","LU0976567544.SGD","LU1496350502.SGD","LU0128525929.USD","LU0052756011.USD","LU0047473722.SGD","LU0859254822.USD","LU0310800379.SGD","LU0949170772.SGD","LU1273509221.SGD","LU1829250122.USD","LU1051770623.HKD","IE00B3T34201.USD","LU1923622614.USD","LU1170363599.USD","LU0827474353.SGD","LU0203345920.USD","LU0784384876.USD","LU0708994859.HKD","LU2433249047.HKD","LU2357627491.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1142104638","title":"异动解读｜Ionis Pharmaceuticals盘前下跌14.75%，核心管线三期试验未达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1142104638","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1142104638?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 16:20","pubTimestamp":1783585239,"startTime":"0","endTime":"0","summary":"7月9日，Ionis Pharmaceuticals盘前下跌14.75%，报74.68美元/股，成交额8.62万美元。消息面上，Ionis与合作伙伴阿斯利康宣布，其药物Eplontersen针对转甲状腺素蛋白介导的淀粉样心肌病的三期临床试验Cardio-Ttransform未能达到主要疗效终点。Ionis与阿斯利康计划继续分析完整数据，并于8月欧洲心脏病学会大会上公布结果。Ionis是一家商业阶段生物技术公司，拥有七种已上市药物，管线覆盖神经病学、心脏代谢疾病等领域，此次ATTR-CM试验失败对其心脏代谢管线构成重大挫折。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650941777","title":"阿斯利康因心脏病药物晚期临床试验失败，成为富时100指数中跌幅最大的个股","url":"https://stock-news.laohu8.com/highlight/detail?id=2650941777","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650941777?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 15:26","pubTimestamp":1783581986,"startTime":"0","endTime":"0","summary":"BUZZ-阿斯利康因心脏病药物晚期临床试验失败，成为富时100指数中跌幅最大的个股7月9日-** 阿斯利康（AZN.L）股价一度暴跌9.6%至12,874便士；有望创下自2017年以来最惨淡的一天** AZN成为富时100指数.FTSE中跌幅最大的个股，该指数下跌0.4%** 该公司表示，其与Ionis（IONS.O）合作研发的神经疾病药物Wainua，在晚期临床试验中 (link) 未能达到降低心血管死亡率及心血管疾病复发率的主要目标** 今年以来，AZN股价下跌6%","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260709:nL4S43B0KZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2237443895.HKD","LU2433249047.HKD","LU1003077747.HKD","LU2357627491.SGD","IE00BFTCPJ56.SGD","LU0203347892.USD","LU1261432733.SGD","LU0553294199.USD","LU0047473722.SGD","LU0857590862.USD","LU0976567544.SGD","LU0859254822.USD","LU0432979614.USD","LU1119994496.HKD","LU1496350502.SGD","LU1267930227.SGD","LU0266013472.USD","LU1003076772.USD","AZN.UK","LU1481600234.SGD","LU0128525929.USD","LU1989772923.USD","LU0887340254.USD","LU2125909593.SGD","IE0002141913.USD","LU1323610961.USD","IE00B2B36J28.USD","LU0058720904.USD","LU1023059063.AUD","LU1061106388.HKD","LU2023251221.USD","03165","LU2539964713.USD","LU2237443382.USD","LU0345777147.USD","LU0575583348.USD","IONS","LU1983299246.USD","LU0114720955.EUR","LU0203345920.USD","LU1481599808.USD","LU1170363599.USD","LU1291159041.SGD","LU0949170772.SGD","LU0557290698.USD","IE00BKPKM643.USD","LU1267930813.SGD","LU1019634622.SGD","LU0128525689.USD","LU0122379950.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650462469","title":"阿斯利康与Ionis合作研发的药物在晚期心脏病临床试验中未能达到主要目标","url":"https://stock-news.laohu8.com/highlight/detail?id=2650462469","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650462469?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 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Inc宣布，其针对药物Eplontersen开展的三期心脏转归临床试验“Cardio-Ttransform”，在截至第140周的分析中未能达到主要研究终点。\n该试验旨在评估Eplontersen在特定患者群体中的心血管获益。尽管未能达到预设的主要终点，但公司表示，试验过程中收集到的全面数据正在进行深入分析，以评估药物的整体获益风险特征，并为未来的开发决策提供依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1138721848","title":"Eplontersen治疗转甲状腺素蛋白介导淀粉样心肌病成人患者的Cardio-Ttransform三期试验最新进展","url":"https://stock-news.laohu8.com/highlight/detail?id=1138721848","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1138721848?lang=zh_cn&edition=fundamental","pubTime":"2026-07-09 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