美股详情

本页面由Tiger Trade Technology Pte. Ltd.提供服务

Karyopharm Therapeutics Inc.

1.86

-0.1000-5.10%

盘后：1.870.0100+0.54%16:58 EDT

成交量：83.99万

成交额：157.52万

市值：4,215.31万

市盈率：-0.14

高：1.96

开：1.95

低：1.83

收：1.96

52周最高：10.99

52周最低：1.79

股本：2,266.29万

流通股本：1,706.56万

量比：0.83

换手率：4.92%

股息：- -

股息率：- -

每股收益(TTM):-13.0816

每股收益(LYR):-17.9300

净资产收益率：-891.05%

总资产收益率：-47.61%

市净率：-0.13

市盈率(LYR):-0.10

数据加载中...

总览公司新闻资讯公告

Karyopharm Therapeutics 携手 Centerview Partners，积极评估融资与战略替代方案

Karyopharm Therapeutics：计划于8月提交Selinexor联合Ruxolitinib治疗骨髓纤维化的sNDA申请按计划推进

Karyopharm 公布2026年第二季度财务业绩，并强调骨髓纤维化sNDA申报工作持续推进

Karyopharm因子宫内膜癌临床试验未达预期而股价创下历史新低

美国研究综述-苹果、亚马逊、万事达卡

Karyopharm Therapeutics 申请优先审评：Selinexor联合Ruxolitinib提交补充新药申请

Karyopharm计划提交Selinexor联合Ruxolitinib治疗骨髓纤维化的加速审批补充新药申请

Karyopharm骨髓纤维化三期Sentry试验获选EHA 2026最新突破性口头报告

Karyopharm公布2026年第一季度财务业绩并完成子宫内膜癌三期试验患者招募

美国研究综述-东西银行集团、瑞莱斯、标普全球

美国研究综述-弗格森企业、哈特福德保险集团、摩根大通

BUZZ-券商观点：Karyopharm 公司的抗癌药物试验结果限制了监管机会

BUZZ--美国股票走势-DexCom、Ocugen、雅诗兰黛

Karyopharm Therapeutics股价盘前飙升16%，其血癌药物在后期研究中达成两大主要目标之一

BUZZ-Karyopharm 股价上涨，因血癌药物达到研究两大主要目标之一

Karyopharm Therapeutics的血癌药物在研究中实现了两大目标之一

Karyopharm将与美国FDA会面商讨Sentry试验数据及潜在sNDA申请事宜

Karyopharm骨髓纤维化三期Sentry试验达成首个共同主要终点，脾脏体积缩小呈现统计学显著改善

Karyopharm Therapeutics修订融资条款取消50%资金用于提升最低流动性要求的限制

Karyopharm Therapeutics Inc. 修订协议允许公司延期付款至2026年9月——SEC文件披露

{"basename":"/hans","ssrTDKData":{"titleTemplate":"%s - 老虎证券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎证券,老虎证券开户,老虎券商,老虎证券官网,老虎证券app,tigertrade老虎证券,股票,炒股,新加坡股票交易平台,投资,投资理财","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.itiger.com/hans/stock/KPTI/news"},"companyName":"老虎证券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"KPTI","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"KPTI\",,,,,undefined,":{"symbol":"KPTI","market":"US","secType":"STK","nameCN":"Karyopharm Therapeutics Inc.","latestPrice":1.86,"timestamp":1787601600000,"preClose":1.96,"halted":0,"volume":839902,"hourTrading":{"tag":"盘后","latestPrice":1.87,"preClose":1.86,"latestTime":"16:58 EDT","volume":3023,"amount":5627.964445,"timestamp":1787605109252,"change":0.01,"changeRate":0.005376,"amplitude":0.010753},"delay":0,"changeRate":-0.05102040816326524,"floatShares":17065600,"shares":22662943,"eps":-13.0816,"marketStatus":"盘后交易","change":-0.1,"latestTime":"08-24 17:07:57 EDT","open":1.95,"high":1.96,"low":1.83,"amount":1575164.5573594,"amplitude":0.066327,"askPrice":1.87,"askSize":164,"bidPrice":1.84,"bidSize":250,"shortable":3,"etf":0,"ttmEps":-13.0816,"tradingStatus":3,"nextMarketStatus":{"tag":"收盘","tradingStatus":0,"beginTime":1787616000000},"marketStatusCode":4,"adr":0,"adrRate":0,"listingDate":1383714000000,"exchange":"NASDAQ","adjPreClose":1.96,"preHourTrading":{"tag":"盘前","latestPrice":1.946,"preClose":1.96,"latestTime":"09:25 EDT","volume":72118,"amount":141356.5878848,"timestamp":1787577941030,"change":-0.014,"changeRate":-0.007143,"amplitude":0.038776},"postHourTrading":{"tag":"盘后","latestPrice":1.87,"preClose":1.86,"latestTime":"16:58 EDT","volume":3023,"amount":5627.964445,"timestamp":1787605109252,"change":0.01,"changeRate":0.005376,"amplitude":0.010753},"volumeRatio":0.82873,"impliedVol":1.4098,"impliedVolPercentile":0.4183},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"KPTI\",,,,,undefined,":{"symbol":"KPTI","floatShares":17065600,"roa":"-47.61%","roe":"-891.05%","lyrEps":-17.93,"volumeRatio":0.82873,"shares":22662943,"dividePrice":0,"high":1.96,"amplitude":0.066327,"preClose":1.96,"low":1.83,"week52Low":1.79,"pbRate":"-0.13","psRate":"0.29","week52High":10.99,"institutionHeld":0,"latestPrice":1.86,"committee":0.207729,"eps":-13.0816,"divideRate":0,"volume":839902,"delay":0,"ttmEps":-13.0816,"open":1.95,"prevYearClose":7.36,"prevWeekClose":1.96,"prevMonthClose":1.92,"prevQuarterClose":9.77,"fiveDayClose":1.81,"twentyDayClose":7.09,"sixtyDayClose":9.11},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/KPTI\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-13","symbol":"KPTI","fiscalQuarterEnding":"2026/06","expectedEps":-1.53,"name":null,"time":"盘前","type":"earning","dateTimestamp":1786593600000,"reportTimeType":"pre","actualEps":-2.32},{"market":"US","date":"2026-05-14","symbol":"KPTI","fiscalQuarterEnding":"2026/03","expectedEps":-1.45,"name":null,"time":"盘前","type":"earning","dateTimestamp":1778731200000,"reportTimeType":"pre","actualEps":-1.24},{"market":"US","date":"2026-02-12","symbol":"KPTI","fiscalQuarterEnding":"2025/12","expectedEps":-2.26,"name":null,"time":"盘前","type":"earning","dateTimestamp":1770872400000,"reportTimeType":"pre","actualEps":-3.6},{"date":"2026-01-12","symbol":"KPTI","type":"earning","reportTimeType":"pre","market":"US","fiscalQuarterEnding":null,"expectedEps":null,"defaultRemindTime":1768208400000,"name":null,"time":"盘前","dateTimestamp":1768194000000,"actualEps":null},{"market":"US","date":"2025-11-03","symbol":"KPTI","fiscalQuarterEnding":"2025/09","expectedEps":-3.3,"name":null,"time":"盘前","type":"earning","dateTimestamp":1762146000000,"reportTimeType":"pre","actualEps":-3.82}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"KPTI\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"KPTI\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2,"buy":0.6,"hold":0.2,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.6,"analysts":5,"updateTime":1785556800000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/KPTI\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"KPTI","date":"2026-08-21","current":-0.143331,"percent":0.999186,"low":-8.777863,"twenty":-3.263757,"median":-1.105825,"eighty":-0.729154,"high":-0.182671,"avg":-1.809695,"sd":1.423808,"marketCap":41280257},"quantilePoints":[{"date":"2021-08-27","current":-2.033479,"twenty":-6.178113,"median":-4.217056,"eighty":-3.286193,"marketCap":422784650},{"date":"2021-09-03","current":-2.069791,"twenty":-6.178113,"median":-4.217056,"eighty":-3.26987,"marketCap":430334376},{"date":"2021-09-10","current":-2.102472,"twenty":-6.178113,"median":-4.217056,"eighty":-3.26987,"marketCap":437129129},{"date":"2021-09-17","current":-2.204146,"twenty":-6.178113,"median":-4.217056,"eighty":-3.26987,"marketCap":458268362},{"date":"2021-09-24","current":-2.273139,"twenty":-6.178113,"median":-4.217056,"eighty":-3.263434,"marketCap":472612841},{"date":"2021-10-01","current":-2.142415,"twenty":-6.178113,"median":-4.217056,"eighty":-3.244364,"marketCap":445433828},{"date":"2021-10-08","current":-2.069791,"twenty":-6.178113,"median":-4.217056,"eighty":-3.226402,"marketCap":430334376},{"date":"2021-10-15","current":-2.029848,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":422029677},{"date":"2021-10-22","current":-1.913649,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":397870554},{"date":"2021-10-29","current":-1.982642,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":412215034},{"date":"2021-11-05","current":-3.08082,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":635354458},{"date":"2021-11-12","current":-3.110126,"twenty":-6.178113,"median":-4.217056,"eighty":-3.191989,"marketCap":641398258},{"date":"2021-11-19","current":-2.773104,"twenty":-6.178113,"median":-4.217056,"eighty":-3.171935,"marketCap":571894559},{"date":"2021-11-26","current":-2.663206,"twenty":-6.178113,"median":-4.217056,"eighty":-3.152248,"marketCap":549230310},{"date":"2021-12-03","current":-2.461725,"twenty":-6.178113,"median":-4.217056,"eighty":-3.122043,"marketCap":507679186},{"date":"2021-12-10","current":-2.194306,"twenty":-6.178113,"median":-4.217056,"eighty":-3.077558,"marketCap":452529513},{"date":"2021-12-17","current":-2.252918,"twenty":-6.178113,"median":-4.217056,"eighty":-3.041599,"marketCap":464617112},{"date":"2021-12-23","current":-2.692512,"twenty":-6.178113,"median":-4.217056,"eighty":-3.015867,"marketCap":555274110},{"date":"2021-12-31","current":-2.35549,"twenty":-6.178113,"median":-4.217056,"eighty":-2.991773,"marketCap":485770412},{"date":"2022-01-07","current":-2.586277,"twenty":-6.177382,"median":-4.216189,"eighty":-2.951041,"marketCap":533365335},{"date":"2022-01-14","current":-2.945279,"twenty":-6.177382,"median":-4.216189,"eighty":-2.925652,"marketCap":607401883},{"date":"2022-01-21","current":-3.033197,"twenty":-6.177382,"median":-4.216189,"eighty":-2.908348,"marketCap":625533283},{"date":"2022-01-28","current":-3.128443,"twenty":-6.177382,"median":-4.216189,"eighty":-2.906995,"marketCap":645175632},{"date":"2022-02-04","current":-3.568037,"twenty":-6.177382,"median":-4.216189,"eighty":-2.906995,"marketCap":735832630},{"date":"2022-02-11","current":-6.238509,"twenty":-6.180304,"median":-4.234673,"eighty":-2.906995,"marketCap":774124120},{"date":"2022-02-18","current":-8.777863,"twenty":-6.208868,"median":-4.248181,"eighty":-2.906995,"marketCap":1089227480},{"date":"2022-02-25","current":-6.403323,"twenty":-6.240007,"median":-4.257032,"eighty":-2.906995,"marketCap":794575540},{"date":"2022-03-04","current":-3.770193,"twenty":-6.251665,"median":-4.26161,"eighty":-2.906995,"marketCap":467835694},{"date":"2022-03-11","current":-4.038125,"twenty":-6.251665,"median":-4.254328,"eighty":-2.906995,"marketCap":501082901},{"date":"2022-03-18","current":-4.58037,"twenty":-6.251665,"median":-4.26161,"eighty":-2.906995,"marketCap":568368914},{"date":"2022-03-25","current":-4.663301,"twenty":-6.251665,"median":-4.282008,"eighty":-2.906995,"marketCap":578659716},{"date":"2022-04-01","current":-5.141752,"twenty":-6.251665,"median":-4.29009,"eighty":-2.906995,"marketCap":638029728},{"date":"2022-04-08","current":-5.184068,"twenty":-6.251665,"median":-4.298174,"eighty":-2.906995,"marketCap":643280680},{"date":"2022-04-14","current":-4.992066,"twenty":-6.251665,"median":-4.351584,"eighty":-2.906995,"marketCap":619455470},{"date":"2022-04-22","current":-4.300857,"twenty":-6.251665,"median":-4.367129,"eighty":-2.906995,"marketCap":533684712},{"date":"2022-04-29","current":-3.904052,"twenty":-6.251665,"median":-4.367129,"eighty":-2.906995,"marketCap":484445944},{"date":"2022-05-06","current":-4.467939,"twenty":-6.251665,"median":-4.381025,"eighty":-2.906995,"marketCap":482863561},{"date":"2022-05-13","current":-3.924144,"twenty":-6.251665,"median":-4.381025,"eighty":-2.906995,"marketCap":424093983},{"date":"2022-05-20","current":-4.276876,"twenty":-6.251665,"median":-4.381025,"eighty":-2.906995,"marketCap":462214791},{"date":"2022-05-27","current":-4.688396,"twenty":-6.251665,"median":-4.393149,"eighty":-2.906995,"marketCap":506689066},{"date":"2022-06-03","current":-4.592865,"twenty":-6.251665,"median":-4.413146,"eighty":-2.906995,"marketCap":496364681},{"date":"2022-06-10","current":-4.041721,"twenty":-6.251665,"median":-4.422403,"eighty":-2.906995,"marketCap":436800919},{"date":"2022-06-17","current":-3.262771,"twenty":-6.251665,"median":-4.422403,"eighty":-2.906995,"marketCap":352617469},{"date":"2022-06-24","current":-3.799218,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":410592864},{"date":"2022-07-01","current":-3.47588,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":375648790},{"date":"2022-07-08","current":-3.858006,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":416946332},{"date":"2022-07-15","current":-3.461183,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":374060423},{"date":"2022-07-22","current":-3.27012,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":353411653},{"date":"2022-07-29","current":-3.123148,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":337527983},{"date":"2022-08-05","current":-3.6068,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":373494962},{"date":"2022-08-12","current":-4.169399,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":431753792},{"date":"2022-08-19","current":-4.21564,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":436542189},{"date":"2022-08-26","current":-3.945901,"twenty":-6.253625,"median":-4.431432,"eighty":-2.906836,"marketCap":408609873},{"date":"2022-09-02","current":-4.038383,"twenty":-6.253625,"median":-4.431432,"eighty":-2.906836,"marketCap":418186667},{"date":"2022-09-09","current":-4.123158,"twenty":-6.253625,"median":-4.431432,"eighty":-2.906836,"marketCap":426965395},{"date":"2022-09-16","current":-3.884246,"twenty":-6.253625,"median":-4.431329,"eighty":-2.906836,"marketCap":402225344},{"date":"2022-09-23","current":-3.391009,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":351149110},{"date":"2022-09-30","current":-4.207933,"twenty":-6.253625,"median":-4.419107,"eighty":-2.906836,"marketCap":435744123},{"date":"2022-10-07","current":-4.269588,"twenty":-6.253625,"median":-4.407185,"eighty":-2.906836,"marketCap":442128652},{"date":"2022-10-14","current":-3.691575,"twenty":-6.253625,"median":-4.365357,"eighty":-2.906836,"marketCap":382273690},{"date":"2022-10-21","current":-3.506611,"twenty":-6.253625,"median":-4.320057,"eighty":-2.906836,"marketCap":363120102},{"date":"2022-10-28","current":-3.907367,"twenty":-6.253625,"median":-4.320057,"eighty":-2.906836,"marketCap":404619543},{"date":"2022-11-04","current":-4.368078,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":384674823},{"date":"2022-11-11","current":-5.215891,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":459337447},{"date":"2022-11-18","current":-4.580032,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":403340479},{"date":"2022-11-25","current":-4.552385,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":400905828},{"date":"2022-12-02","current":-4.745908,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":417948383},{"date":"2022-12-09","current":-4.331217,"twenty":-6.253625,"median":-4.294457,"eighty":-2.906836,"marketCap":381428622},{"date":"2022-12-16","current":-2.85676,"twenty":-6.253625,"median":-4.284224,"eighty":-2.903809,"marketCap":251580580},{"date":"2022-12-23","current":-3.32961,"twenty":-6.253625,"median":-4.284224,"eighty":-2.862041,"marketCap":293222102},{"date":"2022-12-30","current":-4.370917,"twenty":-6.253625,"median":-4.294457,"eighty":-2.862041,"marketCap":384924767},{"date":"2023-01-06","current":-4.512329,"twenty":-6.253625,"median":-4.322002,"eighty":-2.862041,"marketCap":397378216},{"date":"2023-01-13","current":-4.24236,"twenty":-6.253625,"median":-4.320057,"eighty":-2.862041,"marketCap":373603451},{"date":"2023-01-20","current":-4.33235,"twenty":-6.253625,"median":-4.322002,"eighty":-2.862041,"marketCap":381528372},{"date":"2023-01-27","current":-4.088093,"twenty":-6.253625,"median":-4.294457,"eighty":-2.862041,"marketCap":360017871},{"date":"2023-02-03","current":-4.370917,"twenty":-6.253625,"median":-4.284224,"eighty":-2.862041,"marketCap":384924767},{"date":"2023-02-10","current":-4.165226,"twenty":-6.253625,"median":-4.269527,"eighty":-2.862041,"marketCap":366810661},{"date":"2023-02-17","current":-2.43428,"twenty":-6.240783,"median":-4.262179,"eighty":-2.84267,"marketCap":402364561},{"date":"2023-02-24","current":-2.057138,"twenty":-6.238604,"median":-4.24236,"eighty":-2.823533,"marketCap":340026390},{"date":"2023-03-03","current":-2.146281,"twenty":-6.180304,"median":-4.224661,"eighty":-2.781626,"marketCap":354760866},{"date":"2023-03-10","current":-2.057138,"twenty":-6.152907,"median":-4.208959,"eighty":-2.75484,"marketCap":340026390},{"date":"2023-03-17","current":-2.331423,"twenty":-6.11274,"median":-4.196041,"eighty":-2.706336,"marketCap":385363242},{"date":"2023-03-24","current":-2.276566,"twenty":-6.11274,"median":-4.183771,"eighty":-2.661741,"marketCap":376295871},{"date":"2023-03-31","current":-2.667422,"twenty":-6.111964,"median":-4.173741,"eighty":-2.649856,"marketCap":440900885},{"date":"2023-04-06","current":-2.681136,"twenty":-6.111964,"median":-4.146073,"eighty":-2.649856,"marketCap":443167728},{"date":"2023-04-14","current":-2.978326,"twenty":-6.11274,"median":-4.128054,"eighty":-2.647561,"marketCap":492290498},{"date":"2023-04-21","current":-2.619824,"twenty":-6.11274,"median":-4.108854,"eighty":-2.641981,"marketCap":433033309},{"date":"2023-04-28","current":-2.412996,"twenty":-6.11274,"median":-4.086917,"eighty":-2.626336,"marketCap":398846469},{"date":"2023-05-05","current":-1.997872,"twenty":-6.087907,"median":-4.049743,"eighty":-2.6213,"marketCap":315699670},{"date":"2023-05-12","current":-1.911983,"twenty":-6.00906,"median":-4.038383,"eighty":-2.601613,"marketCap":302127687},{"date":"2023-05-19","current":-1.738822,"twenty":-5.954697,"median":-4.012327,"eighty":-2.595069,"marketCap":274765179},{"date":"2023-05-26","current":-1.738822,"twenty":-5.924166,"median":-3.998811,"eighty":-2.559679,"marketCap":274765179},{"date":"2023-06-02","current":-1.587306,"twenty":-5.912525,"median":-3.987794,"eighty":-2.54416,"marketCap":250822985},{"date":"2023-06-09","current":-1.688317,"twenty":-5.903664,"median":-3.97614,"eighty":-2.515942,"marketCap":266784448},{"date":"2023-06-16","current":-1.493511,"twenty":-5.881585,"median":-3.961315,"eighty":-2.495534,"marketCap":236001627},{"date":"2023-06-23","current":-1.464651,"twenty":-5.820152,"median":-3.946448,"eighty":-2.476356,"marketCap":231441209},{"date":"2023-06-30","current":-1.32035,"twenty":-5.781367,"median":-3.938194,"eighty":-2.46815,"marketCap":208639119},{"date":"2023-07-07","current":-1.096684,"twenty":-5.767239,"median":-3.926795,"eighty":-2.461725,"marketCap":173295880},{"date":"2023-07-14","current":-1.183265,"twenty":-5.753441,"median":-3.916124,"eighty":-2.45079,"marketCap":186977134},{"date":"2023-07-21","current":-1.16162,"twenty":-5.738623,"median":-3.902098,"eighty":-2.423309,"marketCap":183556821},{"date":"2023-07-28","current":-1.21934,"twenty":-5.710966,"median":-3.89966,"eighty":-2.39588,"marketCap":192677657},{"date":"2023-08-04","current":-1.46188,"twenty":-5.691895,"median":-3.884246,"eighty":-2.372906,"marketCap":206981717},{"date":"2023-08-11","current":-1.348806,"twenty":-5.675808,"median":-3.862584,"eighty":-2.346821,"marketCap":190972081},{"date":"2023-08-18","current":-1.356883,"twenty":-5.661094,"median":-3.856444,"eighty":-2.327554,"marketCap":192115627},{"date":"2023-08-25","current":-1.122659,"twenty":-5.642939,"median":-3.835297,"eighty":-2.279163,"marketCap":158952810},{"date":"2023-09-01","current":-1.033816,"twenty":-5.621148,"median":-3.822591,"eighty":-2.226817,"marketCap":146373811},{"date":"2023-09-08","current":-0.936895,"twenty":-5.610619,"median":-3.805269,"eighty":-2.211408,"marketCap":132651266},{"date":"2023-09-15","current":-1.049969,"twenty":-5.594688,"median":-3.791764,"eighty":-2.194285,"marketCap":148660902},{"date":"2023-09-22","current":-1.009586,"twenty":-5.573404,"median":-3.784057,"eighty":-2.163015,"marketCap":142943175},{"date":"2023-09-29","current":-1.106506,"twenty":-5.553533,"median":-3.768644,"eighty":-2.142415,"marketCap":156665719},{"date":"2023-10-06","current":-1.058046,"twenty":-5.535997,"median":-3.751711,"eighty":-2.124259,"marketCap":149804447},{"date":"2023-10-13","current":-1.009586,"twenty":-5.530362,"median":-3.745537,"eighty":-2.113365,"marketCap":142943175},{"date":"2023-10-20","current":-0.856129,"twenty":-5.528881,"median":-3.711035,"eighty":-2.099567,"marketCap":121215812},{"date":"2023-10-27","current":-0.647104,"twenty":-5.530246,"median":-3.695288,"eighty":-2.090126,"marketCap":91620857},{"date":"2023-11-03","current":-0.622876,"twenty":-5.530246,"median":-3.680928,"eighty":-2.070428,"marketCap":87058111},{"date":"2023-11-10","current":-0.56813,"twenty":-5.530246,"median":-3.667547,"eighty":-2.054937,"marketCap":79406415},{"date":"2023-11-17","current":-0.570752,"twenty":-5.530246,"median":-3.644676,"eighty":-2.02705,"marketCap":79772924},{"date":"2023-11-24","current":-0.605088,"twenty":-5.530246,"median":-3.63006,"eighty":-2.008787,"marketCap":84571898},{"date":"2023-12-01","current":-0.630983,"twenty":-5.530246,"median":-3.594199,"eighty":-1.984272,"marketCap":88191173},{"date":"2023-12-08","current":-0.687115,"twenty":-5.530188,"median":-3.575973,"eighty":-1.952485,"marketCap":96036751},{"date":"2023-12-15","current":-0.688509,"twenty":-5.530188,"median":-3.560803,"eighty":-1.928904,"marketCap":96231459},{"date":"2023-12-22","current":-0.62328,"twenty":-5.530188,"median":-3.557127,"eighty":-1.913316,"marketCap":87114553},{"date":"2023-12-29","current":-0.756605,"twenty":-5.530246,"median":-3.558965,"eighty":-1.898992,"marketCap":105749233},{"date":"2024-01-05","current":-0.676053,"twenty":-5.530304,"median":-3.549366,"eighty":-1.893314,"marketCap":94490542},{"date":"2024-01-12","current":-0.604924,"twenty":-5.530304,"median":-3.523541,"eighty":-1.878246,"marketCap":84548992},{"date":"2024-01-19","current":-0.593206,"twenty":-5.530362,"median":-3.503855,"eighty":-1.861175,"marketCap":82911156},{"date":"2024-01-26","current":-0.717599,"twenty":-5.530304,"median":-3.501098,"eighty":-1.83927,"marketCap":100297415},{"date":"2024-02-02","current":-0.737758,"twenty":-5.530304,"median":-3.501098,"eighty":-1.821001,"marketCap":103114952},{"date":"2024-02-09","current":-1.237381,"twenty":-5.530304,"median":-3.501098,"eighty":-1.803757,"marketCap":172946326},{"date":"2024-02-16","current":-1.065295,"twenty":-5.530304,"median":-3.497357,"eighty":-1.784998,"marketCap":148894188},{"date":"2024-02-23","current":-0.925987,"twenty":-5.530304,"median":-3.493617,"eighty":-1.76886,"marketCap":129423409},{"date":"2024-03-01","current":-0.931533,"twenty":-5.530246,"median":-3.493617,"eighty":-1.765064,"marketCap":133301400},{"date":"2024-03-08","current":-1.230286,"twenty":-5.530246,"median":-3.493617,"eighty":-1.765064,"marketCap":176052636},{"date":"2024-03-15","current":-1.077505,"twenty":-5.530246,"median":-3.493617,"eighty":-1.765064,"marketCap":154189891},{"date":"2024-03-22","current":-1.141834,"twenty":-5.530246,"median":-3.493617,"eighty":-1.75222,"marketCap":163395257},{"date":"2024-03-28","current":-1.19008,"twenty":-5.530246,"median":-3.493617,"eighty":-1.741713,"marketCap":170299282},{"date":"2024-04-05","current":-1.069464,"twenty":-5.530304,"median":-3.493617,"eighty":-1.717331,"marketCap":153039220},{"date":"2024-04-12","current":-1.077505,"twenty":-5.530304,"median":-3.493617,"eighty":-1.708028,"marketCap":154189891},{"date":"2024-04-19","current":-1.041769,"twenty":-5.530304,"median":-3.493617,"eighty":-1.692185,"marketCap":149076142},{"date":"2024-04-26","current":-0.862715,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":123453680},{"date":"2024-05-03","current":-0.878993,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":125782994},{"date":"2024-05-10","current":-0.860696,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":125949981},{"date":"2024-05-17","current":-0.912982,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":133601148},{"date":"2024-05-24","current":-0.876784,"twenty":-5.530246,"median":-3.493617,"eighty":-1.679677,"marketCap":128304186},{"date":"2024-05-31","current":-0.807467,"twenty":-5.530246,"median":-3.493617,"eighty":-1.663086,"marketCap":118160637},{"date":"2024-06-07","current":-0.828501,"twenty":-5.530246,"median":-3.493617,"eighty":-1.652426,"marketCap":121238645},{"date":"2024-06-14","current":-0.86861,"twenty":-5.530304,"median":-3.493617,"eighty":-1.621772,"marketCap":127108046},{"date":"2024-06-21","current":-0.807575,"twenty":-5.530362,"median":-3.495487,"eighty":-1.552674,"marketCap":118176450},{"date":"2024-06-28","current":-0.828782,"twenty":-5.531765,"median":-3.501098,"eighty":-1.502169,"marketCap":121279797},{"date":"2024-07-05","current":-0.705372,"twenty":-5.531765,"median":-3.501098,"eighty":-1.463543,"marketCap":103220561},{"date":"2024-07-12","current":-0.819669,"twenty":-5.531765,"median":-3.501098,"eighty":-1.430073,"marketCap":119946230},{"date":"2024-07-15","current":-0.803572,"twenty":-5.531765,"median":-3.501098,"eighty":-1.408574,"marketCap":117590677},{"date":"2024-08-02","current":-0.786708,"twenty":-5.540395,"median":-3.52844,"eighty":-1.378071,"marketCap":115122956},{"date":"2024-08-09","current":-1.162622,"twenty":-5.540395,"median":-3.52844,"eighty":-1.348806,"marketCap":104534798},{"date":"2024-08-16","current":-1.156659,"twenty":-5.540395,"median":-3.52844,"eighty":-1.300346,"marketCap":103998658},{"date":"2024-08-23","current":-1.091622,"twenty":-5.540395,"median":-3.52844,"eighty":-1.26245,"marketCap":98150993},{"date":"2024-08-30","current":-1.06888,"twenty":-5.540395,"median":-3.52844,"eighty":-1.237381,"marketCap":96106181},{"date":"2024-09-06","current":-1.106182,"twenty":-5.540395,"median":-3.52844,"eighty":-1.214203,"marketCap":99460172},{"date":"2024-09-13","current":-1.020345,"twenty":-5.540395,"median":-3.52844,"eighty":-1.19008,"marketCap":91742252},{"date":"2024-09-20","current":-1.024921,"twenty":-5.540395,"median":-3.52844,"eighty":-1.179196,"marketCap":92153708},{"date":"2024-09-27","current":-0.979714,"twenty":-5.540395,"median":-3.52844,"eighty":-1.162622,"marketCap":88089020},{"date":"2024-10-04","current":-1.221696,"twenty":-5.540395,"median":-3.52844,"eighty":-1.156659,"marketCap":109846322},{"date":"2024-10-11","current":-1.174547,"twenty":-5.540395,"median":-3.52844,"eighty":-1.156659,"marketCap":105607077},{"date":"2024-10-18","current":-1.184254,"twenty":-5.540395,"median":-3.52844,"eighty":-1.156659,"marketCap":106479863},{"date":"2024-10-25","current":-1.131559,"twenty":-5.540395,"median":-3.52844,"eighty":-1.155827,"marketCap":101741883},{"date":"2024-10-31","current":-1.165118,"twenty":-5.540395,"median":-3.52844,"eighty":-1.155436,"marketCap":104759228},{"date":"2024-11-08","current":-1.26376,"twenty":-5.541296,"median":-3.5198,"eighty":-1.15523,"marketCap":110552457},{"date":"2024-11-15","current":-1.19944,"twenty":-5.541296,"median":-3.493617,"eighty":-1.15523,"marketCap":104925835},{"date":"2024-11-22","current":-1.113919,"twenty":-5.541296,"median":-3.47588,"eighty":-1.14719,"marketCap":97444559},{"date":"2024-11-29","current":-1.210614,"twenty":-5.541296,"median":-3.463693,"eighty":-1.14719,"marketCap":105903289},{"date":"2024-12-06","current":-1.140851,"twenty":-5.541296,"median":-3.43751,"eighty":-1.145928,"marketCap":99800472},{"date":"2024-12-13","current":-1.037137,"twenty":-5.541296,"median":-3.414129,"eighty":-1.13842,"marketCap":90727702},{"date":"2024-12-20","current":-0.930558,"twenty":-5.537319,"median":-3.387697,"eighty":-1.128401,"marketCap":81404303},{"date":"2024-12-27","current":-0.859506,"twenty":-5.530188,"median":-3.36644,"eighty":-1.123123,"marketCap":75188703},{"date":"2025-01-03","current":-1.162625,"twenty":-5.516937,"median":-3.343606,"eighty":-1.121478,"marketCap":101705253},{"date":"2025-01-10","current":-1.025677,"twenty":-5.508837,"median":-3.312909,"eighty":-1.11771,"marketCap":89725186},{"date":"2025-01-17","current":-1.007316,"twenty":-5.497414,"median":-3.305436,"eighty":-1.112429,"marketCap":88118996},{"date":"2025-01-24","current":-0.992746,"twenty":-5.497414,"median":-3.273794,"eighty":-1.107,"marketCap":86844470},{"date":"2025-01-31","current":-0.957982,"twenty":-5.497414,"median":-3.261546,"eighty":-1.105896,"marketCap":83803273},{"date":"2025-02-07","current":-0.94774,"twenty":-5.497414,"median":-3.175832,"eighty":-1.099644,"marketCap":82907318},{"date":"2025-02-14","current":-0.879508,"twenty":-5.497414,"median":-3.156988,"eighty":-1.094654,"marketCap":76938496},{"date":"2025-02-21","current":-1.007647,"twenty":-5.497414,"median":-3.135466,"eighty":-1.083557,"marketCap":77006432},{"date":"2025-02-28","current":-0.919547,"twenty":-5.497414,"median":-3.112977,"eighty":-1.076519,"marketCap":70273658},{"date":"2025-03-07","current":-0.68498,"twenty":-5.459269,"median":-3.063461,"eighty":-1.066729,"marketCap":52347563},{"date":"2025-03-14","current":-0.764271,"twenty":-5.377449,"median":-3.033537,"eighty":-1.058663,"marketCap":58407088},{"date":"2025-03-21","current":-0.67617,"twenty":-5.323498,"median":-2.978326,"eighty":-1.050101,"marketCap":51674282},{"date":"2025-03-28","current":-0.479046,"twenty":-5.224446,"median":-2.945279,"eighty":-1.041892,"marketCap":36609630},{"date":"2025-04-04","current":-0.425084,"twenty":-5.182452,"median":-2.90636,"eighty":-1.037854,"marketCap":32485787},{"date":"2025-04-11","current":-0.439401,"twenty":-5.097768,"median":-2.855494,"eighty":-1.033601,"marketCap":33579867},{"date":"2025-04-17","current":-0.486754,"twenty":-4.988131,"median":-2.820242,"eighty":-1.024311,"marketCap":37198750},{"date":"2025-04-25","current":-0.657449,"twenty":-4.90474,"median":-2.783037,"eighty":-1.019651,"marketCap":50243561},{"date":"2025-05-02","current":-0.758085,"twenty":-4.802193,"median":-2.732808,"eighty":-1.010806,"marketCap":57934396},{"date":"2025-05-09","current":-0.689678,"twenty":-4.756262,"median":-2.687994,"eighty":-1.007448,"marketCap":52706588},{"date":"2025-05-16","current":-0.745686,"twenty":-4.690954,"median":-2.666869,"eighty":-1.002814,"marketCap":46621762},{"date":"2025-05-23","current":-0.641201,"twenty":-4.668631,"median":-2.639443,"eighty":-0.991544,"marketCap":40089154},{"date":"2025-05-30","current":-0.626,"twenty":-4.606093,"median":-2.61192,"eighty":-0.988921,"marketCap":39138765},{"date":"2025-06-06","current":-0.588689,"twenty":-4.57934,"median":-2.571624,"eighty":-0.98354,"marketCap":36805991},{"date":"2025-06-13","current":-0.602508,"twenty":-4.544148,"median":-2.497361,"eighty":-0.976077,"marketCap":37669981},{"date":"2025-06-20","current":-0.613563,"twenty":-4.525095,"median":-2.464938,"eighty":-0.968885,"marketCap":38361173},{"date":"2025-06-27","current":-0.620472,"twenty":-4.496165,"median":-2.44341,"eighty":-0.961125,"marketCap":38793168},{"date":"2025-07-03","current":-0.606653,"twenty":-4.462711,"median":-2.413709,"eighty":-0.955525,"marketCap":37929178},{"date":"2025-07-11","current":-0.690949,"twenty":-4.419353,"median":-2.38628,"eighty":-0.94965,"marketCap":43199520},{"date":"2025-07-18","current":-0.562433,"twenty":-4.370917,"median":-2.350313,"eighty":-0.944972,"marketCap":35164409},{"date":"2025-07-25","current":-0.612181,"twenty":-4.34425,"median":-2.283059,"eighty":-0.930753,"marketCap":38274774},{"date":"2025-08-01","current":-0.526503,"twenty":-4.321613,"median":-2.22019,"eighty":-0.921603,"marketCap":32918034},{"date":"2025-08-08","current":-0.548614,"twenty":-4.291871,"median":-2.206071,"eighty":-0.917005,"marketCap":34300418},{"date":"2025-08-15","current":-0.326315,"twenty":-4.268071,"median":-2.187423,"eighty":-0.909097,"marketCap":40321442},{"date":"2025-08-22","current":-0.422455,"twenty":-4.25249,"median":-2.149795,"eighty":-0.897627,"marketCap":52201093},{"date":"2025-08-29","current":-0.538946,"twenty":-4.228811,"median":-2.135675,"eighty":-0.890144,"marketCap":66595415},{"date":"2025-09-05","current":-0.47263,"twenty":-4.21564,"median":-2.12104,"eighty":-0.879508,"marketCap":58401057},{"date":"2025-09-12","current":-0.465964,"twenty":-4.197295,"median":-2.11268,"eighty":-0.876852,"marketCap":57577285},{"date":"2025-09-19","current":-0.402104,"twenty":-4.178393,"median":-2.097025,"eighty":-0.869983,"marketCap":49686422},{"date":"2025-09-26","current":-0.467367,"twenty":-4.162571,"median":-2.082501,"eighty":-0.859744,"marketCap":57750711},{"date":"2025-10-03","current":-0.441402,"twenty":-4.136838,"median":-2.059833,"eighty":-0.852257,"marketCap":54542338},{"date":"2025-10-10","current":-0.40842,"twenty":-4.110409,"median":-2.031663,"eighty":-0.841527,"marketCap":50466837},{"date":"2025-10-17","current":-0.423157,"twenty":-4.087399,"median":-2.015323,"eighty":-0.828364,"marketCap":52287806},{"date":"2025-10-24","current":-0.434385,"twenty":-4.048591,"median":-1.980827,"eighty":-0.8194,"marketCap":53675210},{"date":"2025-10-31","current":-0.768209,"twenty":-4.035263,"median":-1.924543,"eighty":-0.814808,"marketCap":94924556},{"date":"2025-11-07","current":-0.71421,"twenty":-4.001921,"median":-1.893677,"eighty":-0.800042,"marketCap":89005572},{"date":"2025-11-14","current":-0.75252,"twenty":-3.983807,"median":-1.863937,"eighty":-0.787249,"marketCap":93779818},{"date":"2025-11-21","current":-0.788094,"twenty":-3.966625,"median":-1.80015,"eighty":-0.784283,"marketCap":98213045},{"date":"2025-11-28","current":-0.768939,"twenty":-3.952294,"median":-1.769857,"eighty":-0.774404,"marketCap":95825923},{"date":"2025-12-05","current":-0.808617,"twenty":-3.936806,"median":-1.738822,"eighty":-0.768355,"marketCap":100770677},{"date":"2025-12-12","current":-0.957753,"twenty":-3.920106,"median":-1.702747,"eighty":-0.768355,"marketCap":119356132},{"date":"2025-12-19","current":-0.871555,"twenty":-3.906704,"median":-1.645027,"eighty":-0.768355,"marketCap":108614080},{"date":"2025-12-26","current":-1.022059,"twenty":-3.900594,"median":-1.598129,"eighty":-0.768355,"marketCap":127370043},{"date":"2026-01-02","current":-1.007009,"twenty":-3.882973,"median":-1.518763,"eighty":-0.768355,"marketCap":125494447},{"date":"2026-01-09","current":-1.2004,"twenty":-3.860185,"median":-1.463265,"eighty":-0.768355,"marketCap":149595012},{"date":"2026-01-16","current":-0.978539,"twenty":-3.835167,"median":-1.428644,"eighty":-0.768355,"marketCap":121946484},{"date":"2026-01-23","current":-0.9756,"twenty":-3.827408,"median":-1.378071,"eighty":-0.768355,"marketCap":121580279},{"date":"2026-01-30","current":-0.974131,"twenty":-3.803157,"median":-1.352845,"eighty":-0.768355,"marketCap":121397176},{"date":"2026-02-06","current":-0.89479,"twenty":-3.785183,"median":-1.314386,"eighty":-0.768355,"marketCap":111509623},{"date":"2026-02-13","current":-0.835007,"twenty":-3.775776,"median":-1.289956,"eighty":-0.768355,"marketCap":163693930},{"date":"2026-02-20","current":-0.904851,"twenty":-3.76825,"median":-1.270277,"eighty":-0.768355,"marketCap":177386170},{"date":"2026-02-27","current":-0.874908,"twenty":-3.750555,"median":-1.253537,"eighty":-0.768355,"marketCap":171516100},{"date":"2026-03-06","current":-0.825314,"twenty":-3.712954,"median":-1.240985,"eighty":-0.768355,"marketCap":161793797},{"date":"2026-03-13","current":-0.739227,"twenty":-3.688987,"median":-1.228001,"eighty":-0.765509,"marketCap":144917347},{"date":"2026-03-20","current":-0.72332,"twenty":-3.668455,"median":-1.212409,"eighty":-0.761437,"marketCap":141798872},{"date":"2026-03-27","current":-0.557402,"twenty":-3.6487,"median":-1.205909,"eighty":-0.756677,"marketCap":109272438},{"date":"2026-04-02","current":-0.669265,"twenty":-3.625972,"median":-1.19992,"eighty":-0.747155,"marketCap":131202099},{"date":"2026-04-10","current":-0.938351,"twenty":-3.584639,"median":-1.19048,"eighty":-0.745958,"marketCap":183953458},{"date":"2026-04-17","current":-0.995848,"twenty":-3.563174,"median":-1.18618,"eighty":-0.745958,"marketCap":195225116},{"date":"2026-04-24","current":-1.006198,"twenty":-3.529112,"median":-1.182503,"eighty":-0.745958,"marketCap":197254015},{"date":"2026-05-01","current":-0.9556,"twenty":-3.517162,"median":-1.1762,"eighty":-0.745958,"marketCap":187334955},{"date":"2026-05-08","current":-1.017697,"twenty":-3.505508,"median":-1.167532,"eighty":-0.745958,"marketCap":199508346},{"date":"2026-05-15","current":-1.023807,"twenty":-3.505508,"median":-1.162834,"eighty":-0.745958,"marketCap":200706125},{"date":"2026-05-22","current":-0.932267,"twenty":-3.496609,"median":-1.161289,"eighty":-0.745958,"marketCap":181763075},{"date":"2026-05-29","current":-1.053716,"twenty":-3.497357,"median":-1.155827,"eighty":-0.745686,"marketCap":205441887},{"date":"2026-06-05","current":-1.049089,"twenty":-3.496609,"median":-1.149081,"eighty":-0.745958,"marketCap":204539837},{"date":"2026-06-12","current":-1.040992,"twenty":-3.460937,"median":-1.141342,"eighty":-0.745958,"marketCap":202961250},{"date":"2026-06-18","current":-1.092644,"twenty":-3.431873,"median":-1.136983,"eighty":-0.745958,"marketCap":213031664},{"date":"2026-06-26","current":-1.099618,"twenty":-3.381209,"median":-1.125752,"eighty":-0.745686,"marketCap":214391440},{"date":"2026-07-02","current":-1.11008,"twenty":-3.358303,"median":-1.125545,"eighty":-0.745686,"marketCap":216431105},{"date":"2026-07-10","current":-1.185635,"twenty":-3.314211,"median":-1.123239,"eighty":-0.745686,"marketCap":231162018},{"date":"2026-07-17","current":-1.090319,"twenty":-3.30428,"median":-1.122268,"eighty":-0.745686,"marketCap":212578405},{"date":"2026-07-24","current":-0.824132,"twenty":-3.267699,"median":-1.11771,"eighty":-0.745686,"marketCap":160680265},{"date":"2026-07-31","current":-0.814833,"twenty":-3.263757,"median":-1.115455,"eighty":-0.745685,"marketCap":158867230},{"date":"2026-08-07","current":-0.226665,"twenty":-3.263757,"median":-1.110137,"eighty":-0.741781,"marketCap":44192738},{"date":"2026-08-14","current":-0.200837,"twenty":-3.263757,"median":-1.106918,"eighty":-0.738013,"marketCap":45136105},{"date":"2026-08-21","current":-0.18368,"twenty":-3.263757,"median":-1.105825,"eighty":-0.729154,"marketCap":41280257}],"updateTime":1787588161144},"$inf$@#url:\"https://stock-news.skytigris.cn/v2/news/list\",params:#symbols:\"KPTI\",pageSize:20,pageCount:1,lang_content:\"cn\",edition:\"fundamental\",,,undefined,":[{"items":[{"id":"1139049633","title":"Karyopharm Therapeutics 携手 Centerview Partners，积极评估融资与战略替代方案","url":"https://stock-news.laohu8.com/highlight/detail?id=1139049633","media":"美股速递","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1139049633?lang=zh_cn&edition=fundamental","pubTime":"2026-08-13 19:36","pubTimestamp":1786620969,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics 正与 Centerview Partners 紧密合作，主动审视融资机会并探索各类战略替代方案。这一举措表明，这家生物制药公司正在大胆寻求资金补充与业务转型的潜在路径，旨在应对当前市场环境的挑战。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1157957381","title":"Karyopharm Therapeutics：计划于8月提交Selinexor联合Ruxolitinib治疗骨髓纤维化的sNDA申请按计划推进","url":"https://stock-news.laohu8.com/highlight/detail?id=1157957381","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1157957381?lang=zh_cn&edition=fundamental","pubTime":"2026-08-13 19:35","pubTimestamp":1786620958,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc. 宣布，其计划于8月提交的补充新药申请（sNDA）正在按既定时间表稳步推进。该申请旨在寻求批准Selinexor与Ruxolitinib的联合疗法，用于治疗骨髓纤维化患者。这一进展标志着公司在关键临床试验成果转化道路上迈出了坚实的一步，为期待新疗法的病患群体带来了潜在希望。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1173189756","title":"Karyopharm 公布2026年第二季度财务业绩，并强调骨髓纤维化sNDA申报工作持续推进","url":"https://stock-news.laohu8.com/highlight/detail?id=1173189756","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1173189756?lang=zh_cn&edition=fundamental","pubTime":"2026-08-13 19:32","pubTimestamp":1786620777,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc. 近日披露了2026年第二季度的财务数据，同时对外释放出明确信号——其针对骨髓纤维化的补充新药申请（sNDA）准备工作正稳步向前推进。这一进展，无疑为市场注入了新的关注焦点。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2656739393","title":"Karyopharm因子宫内膜癌临床试验未达预期而股价创下历史新低","url":"https://stock-news.laohu8.com/highlight/detail?id=2656739393","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2656739393?lang=zh_cn&edition=fundamental","pubTime":"2026-08-01 01:45","pubTimestamp":1785519916,"startTime":"0","endTime":"0","summary":"BUZZ-Karyopharm因子宫内膜癌临床试验未达预期而股价创下历史新低7月31日-** Karyopharm Therapeutics（KPTI.O）股价下跌71.9%，跌至1.97美元的历史最低点** 股价跌破2025年8月创下的3.65美元的52周低点** 该公司周四晚间表示，其用于治疗晚期或复发性子宫内膜癌的维持治疗药物塞利内索（selinexor），在一项晚期临床试验中未能实现显著改","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260731:nL4S43X24R:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2655835829","title":"美国研究综述-苹果、亚马逊、万事达卡","url":"https://stock-news.laohu8.com/highlight/detail?id=2655835829","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2655835829?lang=zh_cn&edition=fundamental","pubTime":"2026-07-31 15:15","pubTimestamp":1785482121,"startTime":"0","endTime":"0","summary":"美国研究综述-苹果、亚马逊、万事达卡路透7月31日-周五，华尔街证券分析师下调了包括苹果、亚马逊和万事达卡在内的多家美国上市公司评级及目标股价。股票按字母顺序排列。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260731:nL4T43X0O3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRS","AAPL","AVY","AMZN","LBO","KPTI","AJG","BXMT","FCF","KKR","CLIX","SPTE","DXCM","HSY","COIA","IP","CUT","TREE","BHRB","DAPP","GPI","GDDY","BMY","ALNY","AX","GDYN","CSW","CMCO","BITQ","ESS","ALRS","EXPO","BELFB","CWH","FLS","XLK","FMC","DXC","GH","CORZ","CFR","GNMX","COIN","ILMN","DRS","H","ARXS","BUSE","HULL","CHDN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1199634645","title":"Karyopharm Therapeutics 申请优先审评：Selinexor联合Ruxolitinib提交补充新药申请","url":"https://stock-news.laohu8.com/highlight/detail?id=1199634645","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1199634645?lang=zh_cn&edition=fundamental","pubTime":"2026-07-31 04:30","pubTimestamp":1785443409,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics 宣布，将寻求优先审评资格，针对其药物 Selinexor 与 Ruxolitinib 联合使用的方案，提交补充新药申请（sNDA）。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1127835746","title":"Karyopharm计划提交Selinexor联合Ruxolitinib治疗骨髓纤维化的加速审批补充新药申请","url":"https://stock-news.laohu8.com/highlight/detail?id=1127835746","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1127835746?lang=zh_cn&edition=fundamental","pubTime":"2026-07-31 04:29","pubTimestamp":1785443394,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc.（KPTI）近日宣布，公司计划提交一项补充新药申请（sNDA），旨在推动其核心药物组合——Selinexor与Ruxolitinib的联合疗法，用于治疗骨髓纤维化。这一申请将走加速审批通道，寻求监管机构的快速审查与批准。此举标志着Karyopharm在血液肿瘤领域迈出关键一步，尤其针对那些对现有治疗反应不佳的患者群体。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1136153850","title":"Karyopharm骨髓纤维化三期Sentry试验获选EHA 2026最新突破性口头报告","url":"https://stock-news.laohu8.com/highlight/detail?id=1136153850","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1136153850?lang=zh_cn&edition=fundamental","pubTime":"2026-06-02 22:05","pubTimestamp":1780409127,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc.宣布，其评估Selinexor联合Ruxolitinib治疗骨髓纤维化的三期SENTRY试验，已被遴选为2026年欧洲血液学协会年会的最新突破性口头报告。这项名为SENTRY的关键性三期试验，旨在评估口服核输出抑制剂Selinexor联合JAK抑制剂Ruxolitinib，在既往未接受过JAK抑制剂治疗的骨髓纤维化患者中的疗效与安全性。入选EHA年会的最新突破性报告环节，彰显了国际血液学界对该试验数据及其潜在临床价值的高度期待。骨髓纤维化是一种罕见的骨髓增生性肿瘤，目前治疗选择有限。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1188494010","title":"Karyopharm公布2026年第一季度财务业绩并完成子宫内膜癌三期试验患者招募","url":"https://stock-news.laohu8.com/highlight/detail?id=1188494010","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1188494010?lang=zh_cn&edition=fundamental","pubTime":"2026-05-14 19:31","pubTimestamp":1778758278,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc. (KPTI) 近日宣布了其2026年第一季度的财务业绩，并同步披露了一项关键临床进展：公司已成功完成其针对子宫内膜癌的三期临床试验的患者招募工作。\n这一进展标志着公司核心管线药物selinexor在拓展新适应症方面迈出了重要一步。子宫内膜癌是女性生殖系统常见的恶性肿瘤，此次三期试验的顺利完成，为后续获取关键疗效数据、寻求监管批准奠定了坚实基础。\n与此同时，公司公布的2026年第一季度财务数据，为投资者评估其当前运营状况与资金储备提供了最新依据。在推进多项后期临床研究的同时，公司的财务状况与研发里程碑共同构成了市场关注的核心焦点。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2630366410","title":"美国研究综述-东西银行集团、瑞莱斯、标普全球","url":"https://stock-news.laohu8.com/highlight/detail?id=2630366410","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2630366410?lang=zh_cn&edition=fundamental","pubTime":"2026-04-27 16:42","pubTimestamp":1777279371,"startTime":"0","endTime":"0","summary":"美国研究综述-东西银行集团、瑞莱斯、标普全球路透4月27日 - 周一，华尔街的证券分析师们上调了多家在美国上市公司的评级和目标股价，其中包括东西银行集团、瑞莱恩斯和标普全球。重点摘要 * 东西银行集团EWBC.O：Piper Sandler将目标价从111美元上调至123美元 * 瑞莱恩斯公司 RS.N：Keybanc将目标价从341美元上调至378美元 * 标普全球公司 SPGI.N：杰富瑞将目标价从500美元上调至535美元以下是路透周一报道的针对美国公司的研究报告摘要。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260427:nL4S41A0M2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["WSFS","NOC","NSC","VRSK","EWBC","SLB","SSB","HAL","TSLW","TSYY","CSGP","SPGI","AMAL","GNRC","DOW","BKR","TSLI","TMDX","PFBC","CHTR","KNSL","TSLG","BANR","MATX","PNFP","EQIX","DLR","GL","NBHC","LBRT","ABCB","GE","IT","HCA","CHE","CRSH","TSLA","PFG","TLA","KPTI","HIG","PG","BX","RS","TSLZ","LMT","TESL","TERN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2623239478","title":"美国研究综述-弗格森企业、哈特福德保险集团、摩根大通","url":"https://stock-news.laohu8.com/highlight/detail?id=2623239478","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2623239478?lang=zh_cn&edition=fundamental","pubTime":"2026-03-30 15:36","pubTimestamp":1774856215,"startTime":"0","endTime":"0","summary":"美国研究综述-弗格森企业、哈特福德保险集团、摩根大通路透3月30日 - 华尔街证券分析师周一调整了对弗格森企业、哈特福德保险集团和摩根大通等几家美国上市公司的评级和目标价。要闻 * 弗格森企业FERG.N：摩根士丹利将目标价从270美元上调至280美元* 哈特福德保险集团HIG.N：KBW将其评级从 \"跑赢大盘 \"下调至 \"市场表现\"。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260330:nL4T40I0JZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4142","GRDN","CCL.UK","SG9999002224.SGD","FERG","LU0820561909.HKD","RF","VRDN","HIG","LU2244417387.USD","LU1989764748.USD","LU2294711713.HKD","LU0823414478.USD","CCL","LU2746668461.USD","FDMT","FLUT","KPTI","BK4566","VOR","IE00BJTD4V19.USD","LU2213496289.HKD","MMM","PTCT","LU0320765992.SGD","LEGN","VSTM","LU0323591593.USD","BPH","LGN","BSX","LU2505996509.AUD","BK4082","BP","LU0950375773.USD","LU0353189680.USD","LU1829250122.USD","JPMO","LU2237443978.SGD","GLUE","EYPT","LU0882574139.USD","FITB","KMI","LU0868494708.USD","CHWY","LU1162221912.USD","JPM","LU2362541513.USD","LU2487616109.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2622078786","title":"BUZZ-券商观点：Karyopharm 公司的抗癌药物试验结果限制了监管机会","url":"https://stock-news.laohu8.com/highlight/detail?id=2622078786","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2622078786?lang=zh_cn&edition=fundamental","pubTime":"2026-03-25 19:49","pubTimestamp":1774439372,"startTime":"0","endTime":"0","summary":"3月25日 - ** Karyopharm Therapeutics KPTI.O周二表示，  在一项针对骨髓纤维化患者的晚期研究中，其疗法导致脾脏体积显著缩小，但只达到了两个主要目标中的一个。** 杰富瑞 称，根据目前的结果，FDA 批准的可能性很低，尽管早期生存信号仍能提供支持。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260325:nL4T40D13G:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621060385","title":"BUZZ--美国股票走势-DexCom、Ocugen、雅诗兰黛","url":"https://stock-news.laohu8.com/highlight/detail?id=2621060385","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621060385?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 21:11","pubTimestamp":1774357883,"startTime":"0","endTime":"0","summary":"nL4N40C0TS ** 阿拉斯加航空集团ALK.N:BUZZ - 由于长期趋势良好，BMO首次给予阿拉斯加航空“跑赢大盘”评级。nL4N40C0UK ** Karyopharm Therapeutics Inc KPTI.O:BUZZ - 血液癌症药物在研究中达到两个主要目标之一，该公司股价大涨 nL6N40C0RF ** DexCom Inc DXCM.O:BUZZ - 因Evercore上调目标价，看好其糖尿病设备有望获得保险覆盖而上涨 nL4N40C0PS ** JetBlue Airways Corp JBLU.O:BUZZ - BMO开始对捷蓝航空进行 \"市场表现 \"评级。nL4N40C0ZA ** Arthur J. Gallagher & Co JG.N:BUZZ - BMO将Gallagher的评级上调至 \"跑赢大盘\"，原因是人工智能带来了生产力方面的好处。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260324:nL4T40C167:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SFD","OCGN","FCXG","LU0577902611.USD","HBBD.SI","LU2257852520.SGD","ECL","RIO.AU","LU0251144936.SGD","JEF","BABW","EL","HOTH","RIO.UK","BABO","FTAI","LU0787776722.HKD","BHP.AU","EVR","LU0329678170.USD","APO","AJG","ARES","BABX","BABU","89988","LU0823417737.USD","WT","JBLU","LU1166156734.SGD","LU0823426480.USD","KPTI","LU0819121731.USD","LU0797268264.HKD","LU0384037296.USD","KBAB","LU1196710864.SGD","00288","ALK","SCCO","ALBmain","BBYY","DXCM","LU2476274308.USD","LU2778985437.USD","CNXC","FCX","LU0345775950.USD"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"1196415628","title":"Karyopharm Therapeutics股价盘前飙升16%，其血癌药物在后期研究中达成两大主要目标之一","url":"https://stock-news.laohu8.com/highlight/detail?id=1196415628","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1196415628?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 19:36","pubTimestamp":1774352204,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc.（股票代码：KPTI）股价在盘前交易中大幅上涨16%，此前该公司宣布其研发的一款血癌药物在一项关键后期研究中，成功达到了预设的两大主要目标之一。这一积极进展为药物的后续审批及商业化前景注入了强劲动力，显著提振了投资者信心。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621309061","title":"BUZZ-Karyopharm 股价上涨，因血癌药物达到研究两大主要目标之一","url":"https://stock-news.laohu8.com/highlight/detail?id=2621309061","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621309061?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 19:35","pubTimestamp":1774352158,"startTime":"0","endTime":"0","summary":"BUZZ-Karyopharm 股价上涨，因血癌药物达到研究两大主要目标之一3月24日 - ** 制药商Karyopharm Therapeutics KPTI.O股价盘前上涨16%至7.78美元** 该公司称其selinexor加ruxolitinib组合药物在骨髓纤维化晚期试验中达到了两个主要目标之一，骨髓纤维化是一种罕见的血癌，会导致骨髓瘢痕和脾脏肿大。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260324:nL4T40C0XN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621306937","title":"Karyopharm Therapeutics的血癌药物在研究中实现了两大目标之一","url":"https://stock-news.laohu8.com/highlight/detail?id=2621306937","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621306937?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 19:12","pubTimestamp":1774350723,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics的血癌药物在研究中实现了两大目标之一路透3月24日 - Karyopharm Therapeutics KPTI.O周二表示，在一项针对罕见血癌患者的后期试验中，该公司的肿瘤疗法显示脾脏体积有了统计学意义上的显著改善，这也是该研究的主要目标之一。然而，该药物未能达到改善患者症状的另一个目标。(为便利非英文母语者，路透将其报导自动化翻译为数种其他语言。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260324:nL4T40C0UF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1116071082","title":"Karyopharm将与美国FDA会面 商讨Sentry试验数据及潜在sNDA申请事宜","url":"https://stock-news.laohu8.com/highlight/detail?id=1116071082","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1116071082?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 19:02","pubTimestamp":1774350132,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc. 即将与美国食品药品监督管理局（FDA）举行会议，重点讨论其Sentry临床试验所获得的数据结果，以及后续提交补充新药申请（sNDA）的潜在可能性。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1185126516","title":"Karyopharm骨髓纤维化三期Sentry试验达成首个共同主要终点，脾脏体积缩小呈现统计学显著改善","url":"https://stock-news.laohu8.com/highlight/detail?id=1185126516","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1185126516?lang=zh_cn&edition=fundamental","pubTime":"2026-03-24 19:01","pubTimestamp":1774350093,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc.（纳斯达克代码：KPTI）宣布，其针对骨髓纤维化患者的三期Sentry临床试验已成功达到首个共同主要终点。数据显示，接受治疗的患者在脾脏体积缩小方面取得统计学上的显著改善。\n该突破性进展为骨髓纤维化治疗领域带来新的希望，标志着Karyopharm在血液恶性肿瘤治疗研发中迈出关键一步。研究人员将继续评估试验的第二个共同主要终点——总症状评分改善情况。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1103779071","title":"Karyopharm Therapeutics修订融资条款 取消50%资金用于提升最低流动性要求的限制","url":"https://stock-news.laohu8.com/highlight/detail?id=1103779071","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1103779071?lang=zh_cn&edition=fundamental","pubTime":"2026-03-03 19:06","pubTimestamp":1772535977,"startTime":"0","endTime":"0","summary":"Karyopharm Therapeutics Inc.近日宣布，已成功完成对其融资协议的修订。根据最新条款，公司取消了原有协议中要求将50%融资收益专项用于提高最低流动性承诺的规定。这一调整将为Karyopharm提供更灵活的资金运用空间，使其能够根据研发进展和商业需求更高效地配置资源。通过解除资金使用限制，Karyopharm可以更自主地决定将融资款项投入最具潜力的领域，包括创新药物研发、临床试验推进以及商业化布局。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1101404919","title":"Karyopharm Therapeutics Inc. 修订协议允许公司延期付款至2026年9月——SEC文件披露","url":"https://stock-news.laohu8.com/highlight/detail?id=1101404919","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1101404919?lang=zh_cn&edition=fundamental","pubTime":"2026-03-03 19:04","pubTimestamp":1772535854,"startTime":"0","endTime":"0","summary":"根据提交给美国证券交易委员会（SEC）的一份文件，Karyopharm Therapeutics Inc. 已通过一项修订协议，获得将特定款项的支付期限推迟至2026年9月的许可。此项安排为公司提供了更灵活的财务运营空间。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":1,"pageCount":1,"totalSize":20,"code":"91000000","status":"200"}]}}