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Denali Therapeutics Inc.

21.03

+1.346.81%

成交量：130.84萬

成交額：2,752.84萬

市值：33.35億

市盈率：-7.08

高：21.48

開：20.32

低：20.17

收：19.69

52周最高：23.77

52周最低：10.57

股本：1.59億

流通股本：1.44億

量比：1.41

換手率：0.91%

股息：- -

股息率：- -

每股收益(TTM):-2.9700

每股收益(LYR):-2.9700

淨資產收益率：-45.69%

總資產收益率：-27.56%

市淨率：3.29

市盈率(LYR):-7.08

資料載入中...

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Denali Therapeutics將公布酶轉運載體項目數據，聚焦亨特綜合徵、A型桑菲利波綜合徵及龐貝病治療進展

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Denali Therapeutics 第三季度運營支出為1.37434億美元

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Denali Therapeutics Inc.：認為修正案中提交的更新信息不會影響BLA的臨床藥理學或獲益風險結論

Denali Therapeutics宣佈其治療MPS II型（亨特綜合徵）藥物Tividenofusp Alfa的生物製品許可申請獲FDA審查延期

Denali Therapeutics Inc.盤中異動快速上漲5.08%

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(DNLI) 近日披露了其2025年第四季度及全年的财务报告，并同步分享了公司在此期间取得的重要业务进展。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4548","DNLI","BK4139","BK4535"],"gpt_icon":0},{"id":"2608002929","title":"Denali Therapeutics：FDA「黑天鵝」驚雷後，TV平台如何攻克血腦屏障，引領CNS罕見病新紀元？","url":"https://stock-news.laohu8.com/highlight/detail?id=2608002929","media":"医道社创新药新...","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2608002929?lang=zh_tw&edition=fundamental","pubTime":"2026-02-01 11:45","pubTimestamp":1769917538,"startTime":"0","endTime":"0","summary":"今天，我想和各位临床医生、药品研发同行们聊聊Denali Therapeutics。这家公司最近因为竞争对手Regenxbio的基因疗法试验被FDA冻结，股价暴涨3.7%，市值冲上33.7亿美元。基因分析显示，AAV病毒载体整合入肿瘤基因组，引发致癌基因突变。RGX-121的PDUFA原定2月8日，现在大概率推迟或重审。Fierce Biotech 2025年报道直言，AAV的“一次性高风险”在CNS领域越来越难站稳脚跟。Fierce Biotech 2025称TV是“BBB突破的游戏改变者”，模块化设计让Denali从罕见病跃升主流神经领域。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2026020113053597a45036&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, .wx-sou","directOrigin":true},"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2026020113053597a45036&s=b","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tencent","symbols":["LENZ","BK4535","DNLI","BK4007","BK4548","TV","BK4539","CNS","BK4100","BK4139","BK4135"],"gpt_icon":0},{"id":"1130865050","title":"Denali Therapeutics將公布酶轉運載體項目數據，聚焦亨特綜合徵、A型桑菲利波綜合徵及龐貝病治療進展","url":"https://stock-news.laohu8.com/highlight/detail?id=1130865050","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1130865050?lang=zh_tw&edition=fundamental","pubTime":"2026-01-30 05:00","pubTimestamp":1769720422,"startTime":"0","endTime":"0","summary":"Denali Therapeutics Inc.近日宣布，将在2026年世界研讨会上展示其酶转运载体技术平台在亨特综合征、A型桑菲利波综合征以及庞贝病治疗领域的多项研究数据。此次公布的数据将涵盖临床前及早期临床研究结果，重点展示酶转运载体技术在突破血脑屏障、提升治疗效率方面的潜力。公司表示，这些数据的发布将为进一步推进罕见病治疗方案的临床开发提供重要科学依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","DNLI","BK4535","BK4548"],"gpt_icon":0},{"id":"1153996693","title":"Denali Therapeutics公布2026年關鍵預期里程碑與優先事項 含Hunter綜合徵療法Tividenofusp Alfa的商業化上市","url":"https://stock-news.laohu8.com/highlight/detail?id=1153996693","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1153996693?lang=zh_tw&edition=fundamental","pubTime":"2026-01-06 21:12","pubTimestamp":1767705146,"startTime":"0","endTime":"0","summary":"Denali Therapeutics Inc. 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，公开发行价值2亿美元的股票和预先筹资的认股权证。(为便利非英文母语者，路透将其报导自动化翻译为数种其他语言。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nL4T3XF1TM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0061475181.USD","LU1668664300.SGD","LU0251142724.SGD","LU2237443382.USD","LU0106831901.USD","IE00B19Z3B42.SGD","BK4535","BK4548","LU2237443895.HKD","IE00BFXG1179.USD","LU0742534661.SGD","LU1894683264.USD","BK4504","BK4127","LU2471134523.USD","LU0345770308.USD","LU2237443622.USD","LU2237443978.SGD","LU1791807156.HKD","LU2265009873.SGD","BK4585","LU2237443465.HKD","IE0004091025.USD","LU0096364046.USD","LU1894683348.USD","LU1868836757.USD","IE00B19Z3581.USD","IE00BSNM7G36.USD","LU2471134879.HKD","LU1804176565.USD","LU1868837136.USD","IE0004086264.USD","LU2471134952.CNY","DNLI","LU2471134796.USD","BK4139","BK4533","BK4552","LU2750360997.AUD","LU1868836914.USD","LU1868836591.USD","LU2237443549.SGD","BK4588","IE0002270589.USD","BK4516","LU1868837300.USD","IE0034235188.USD","LU2237438978.USD","LU0251131958.USD","LU0345770993.USD"],"gpt_icon":0},{"id":"1115187360","title":"Denali 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