Biontech与施贵宝公布Pumitamig全球二期研究数据

投资观察
Dec 09, 2025

12月9日(路透社)- BioNTech SE与施贵宝(Bristol Myers Squibb)首次公布PD-L1XVEGF-A双特异性抗体Pumitamig在晚期三阴性乳腺癌中的全球二期研究数据,显示出令人鼓舞的疗效。Pumitamig联合化疗实现了61.5%的确认客观反应率(CORR)、71.8%的未确认客观反应率(UORR)和92.3%的疾病控制率(DCR),与PD-L1表达水平无关。这些数据与先前在中国进行的1L TNBC I期/II期临床试验中报告的数据一致,并确认了关键III期ROSETTA BREAST-01试验的剂量选择。相关数据将于2025年圣安东尼奥乳腺癌研讨会(SABCS)上公布。

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