生物制药公司Protara Therapeutics宣布，其针对长期肠外营养患者开展的静脉氯化胆碱三期注册性Thrive-3临床试验已完成首位患者给药。该试验旨在评估药物对肠衰竭相关肝损伤的疗效，标志着公司核心管线推进的重要里程碑。基于胆碱缺乏与肝脂肪变性病理机制的紧密关联，此次试验设计包含多重疗效终点，包括肝脏脂肪含量影像学评估与生化指标改善等核心维度。随着首位患者给药完成，后续将加速推进多中心临床入组工作，为潜在的新药申请奠定基础。
生物制药公司Protara Therapeutics宣布，其针对长期肠外营养患者开展的静脉氯化胆碱三期注册性Thrive-3临床试验已完成首位患者给药。该试验旨在评估药物对肠衰竭相关肝损伤的疗效，标志着公司核心管线推进的重要里程碑。基于胆碱缺乏与肝脂肪变性病理机制的紧密关联，此次试验设计包含多重疗效终点，包括肝脏脂肪含量影像学评估与生化指标改善等核心维度。随着首位患者给药完成，后续将加速推进多中心临床入组工作，为潜在的新药申请奠定基础。
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