生物制药公司Sarepta Therapeutics(SRPT)股价今日盘前大跌12.29%,延续了昨日夜盘的下跌趋势,引发市场广泛关注。这一显著跌幅主要源于公司近期遭遇的一系列负面消息,对其核心业务造成重大打击。
据悉,Sarepta Therapeutics计划裁员36%,约500人,这一决定与其基因疗法Elevidys遭遇的重大挫折密切相关。公司披露,使用Elevidys治疗的两名患者不幸身亡,这一事件严重打击了投资者对该疗法的信心。更令人担忧的是,美国食品和药物管理局(FDA)决定对Elevidys增加黑框警告,提示其存在严重的肝脏风险。值得注意的是,Elevidys是FDA批准的唯一一种用于治疗四岁及以上杜氏肌营养不良症患者的基因疗法,这次事件无疑会对Sarepta的核心业务造成重大影响。
尽管公司宣布任命Ryan Wong为新任首席财务官,但这一人事变动似乎未能提振投资者信心。分析人士指出,Sarepta面临的挑战可能会持续一段时间,投资者需密切关注公司后续的应对措施及Elevidys的进一步发展。当前的股价大跌反映了市场对公司前景的担忧,Sarepta Therapeutics面临着重建投资者信心的艰巨任务。
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