CARSGEN-B (02171): Research Updates on CT0596 to be Presented at 2025 ASH Annual Meeting

Stock News
Oct 06

CARSGEN-B (02171) announced that it will present clinical data for CT0596, a BCMA-targeting allogeneic CAR-T cell candidate, at the 67th American Society of Hematology (ASH) Annual Meeting. The abstract and additional information will be released after November 3, 2025, Eastern Time.

CT0596 is a universal CAR-T cell therapy targeting BCMA, developed based on CARSGEN's proprietary THANK-u Plus™ platform, and is currently undergoing investigator-initiated clinical trials in relapsed/refractory multiple myeloma (R/R MM) or plasma cell leukemia (PCL). CT0596 has demonstrated preliminary favorable safety profile and encouraging efficacy signals, with CAR-T cell expansion observed across all predetermined dose groups.

Beyond R/R MM, the company also plans to further explore CT0596 in other plasma cell malignancies as well as autoreactive plasma cell-driven autoimmune diseases. The company anticipates submitting an IND application for this product candidate in the second half of 2025.

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