6月3日，Praxis Precision Medicines盘后下跌8.94%，报258.59美元/股，成交额21.2万美元。
消息面上，公司宣布其针对难治性局灶性发作癫痫的Power1研究未能达到预设的主要疗效终点，这一结果对公司核心管线构成重大挑战。对于临床阶段的生物制药公司而言，关键试验主要终点未达标通常意味着后续开发路径面临高度不确定性。值得注意的是，该试验达到了次要终点50%应答率，且30毫克剂量组在降低癫痫发作频率方面表现更为显著；此外，核心药物Vormatrigine耐受性良好，因不良事件停药率低于10%。但次要终点的积极信号未能抵消主要终点失败带来的市场担忧，股价在盘中大跌15.36%后盘后继续走低。
（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。）
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