IDEAYA Biosciences与阿斯利康达成临床合作 共同推进IDE849联合Imfinzi治疗小细胞肺癌研究

投资观察
Apr 09

IDEAYA Biosciences Inc(简称IDEAYA)于2026年4月8日宣布与阿斯利康制药达成临床合作协定。根据美国证券交易委员会披露文件,双方将针对IDEAYA研发的IDE849与阿斯利康的Imfinzi(度伐利尤单抗)联合疗法,开展针对广泛期小细胞肺癌的临床评估。

根据协议安排,IDEAYA将作为临床试验的申办方,主导研究推进;阿斯利康则负责提供其抗PD-L1抗体Imfinzi。此次合作旨在探索IDE849在DLL3上调实体瘤治疗领域的潜力,目前IDEAYA正在积极推进该药物的全球一期临床试验。

值得注意的是,IDE849作为一款靶向DLL3蛋白的创新疗法,在临床前研究中已显示出对特定肿瘤类型的显著抑制活性。此次与阿斯利康的强强联合,有望加速该药物在难治性肿瘤领域的开发进程。

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