美国食品药品监督管理局（FDA）已正式批准Corcept医疗公司研发的选择性糖皮质激素受体拮抗剂Lifyorli™（Relacorilant）与白蛋白紫杉醇联合用药方案，用于治疗铂类耐药卵巢癌患者。这一重大进展为面临治疗困境的患者提供了新的希望。
Lifyorli™通过精准阻断糖皮质激素受体的活性，有效抑制肿瘤对化疗药物的耐药机制。与白蛋白紫杉醇的协同使用，有望显著提升晚期卵巢癌患者的临床应答率。该获批基于三期临床试验的积极数据，显示联合疗法能延长无进展生存期并改善生活质量。
此次批准标志着靶向激素通路治疗卵巢癌领域的突破。Corcept医疗计划在本季度启动商业化供应，同时开展真实世界疗效追踪研究。
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