异动解读|Arrowhead制药盘中上涨5.06%,阿尔茨海默病siRNA药物临床进展持续催化

行情直击
Jun 18

6月17日,Arrowhead制药盘中上涨5.06%,报80.25美元/股,成交额5127.81万美元。

消息面上,公司近期持续受到ARO-MAPT临床进展催化。该药物基于TRiM BBB平台开发,利用siRNA偶联转铁蛋白受体靶向配体,通过皮下注射给药跨越血脑屏障,在全脑范围内沉默MAPT基因,用于治疗阿尔茨海默病等Tau蛋白病。临床前数据显示,ARO-MAPT在非人灵长类动物中实现高达70-80%的mRNA敲降,覆盖神经元、星形胶质细胞等多种细胞类型。公司已启动1/2a期临床试验,早期数据有望于下半年读出,市场对其CNS递送平台拓展潜力持续给予积极定价。

(以上内容均基于市场公开消息,由程序或算法智能生成,仅作为股价异动提醒,不作为投资建议或交易依据。)

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