Movement Alert|Arrowhead Pharmaceuticals Rises 5.89% in Regular Trading, Preliminary Clinical Data for Alzheimer siRNA Drug Disclosed

Market Focus
Jun 12

On June 11, Arrowhead Pharmaceuticals rose 5.89% in regular trading, trading at $74.995/share, with turnover of $45.59 million.

On the news front, the company disclosed preliminary clinical results for ARO-MAPT7, an siRNA drug developed on its TRiM BBB (blood-brain barrier) platform. The drug utilizes siRNA conjugated with a transferrin receptor-targeting ligand, administered via subcutaneous injection, designed to efficiently cross the blood-brain barrier and silence the MAPT gene throughout the brain for the treatment of Alzheimer's disease and other Tau protein disorders.

This data release marks a key milestone for the company in central nervous system RNA interference therapeutics. The market responded positively to the demonstrated potential of Arrowhead's BBB delivery technology platform, which addresses one of the most significant challenges in neurological drug development — delivering therapeutic agents across the blood-brain barrier.

Within the Biotechnology sector, Amgen gained 5.17%, Gilead Sciences rose 4.67%, AbbVie advanced 0.68%, and Nuvalent added 0.1%.

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