US Stock Alert | Ultragenyx Pharmaceutical (RARE.US) Plummets Over 42% Pre-Market After Late-Stage Trial Failure for Investigational Genetic Bone Disease Drug

Stock News
Dec 29, 2025

Ultragenyx Pharmaceutical (RARE.US) shares experienced a severe sell-off during Monday's pre-market trading session. At the time of writing, the stock was down more than 42%, trading at $19.69. The catalyst for the plunge was the company's announcement that its investigational drug for a specific genetic bone disease failed to meet the primary efficacy endpoint in a late-stage clinical trial.

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