在AD/PD 2026国际会议上，Anavex生命科学公司发布了其AD-004二期b/三期临床试验的最新分析结果。数据显示，口服药物Blarcamesine的治疗效果与早期阿尔茨海默病患者脑容量保留程度之间存在持续一致性关联。
该研究通过脑影像学检测发现，接受Blarcamesine治疗的患者群体相较于对照组，展现出更缓慢的脑萎缩速率。这一发现进一步佐证了该药物通过激活Sigma-1受体蛋白来调控神经元保护机制的潜在作用路径。
研究人员强调，脑容量指标与认知功能评分的协同改善趋势，为Blarcamesine延缓阿尔茨海默病进展的临床价值提供了客观生物学依据。目前该试验仍在进行最终阶段的数据收集与盲态分析。
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