INNOVENT BIO (01801) surged nearly 5% intraday, trading at HK$90.65 by press time, up 3.9%, with a turnover of HK$177 million. The catalyst behind the rally stems from the latest quarterly review of the Hang Seng Index Series, announced on November 21, with changes taking effect on December 8, 2025. INNOVENT BIO will be added as a constituent stock, expanding the index count from 88 to 89.
Notably, on November 20, the company disclosed that its Mazdutide injection (a GCG/GLP-1 dual agonist, R&D code: IBI362) achieved primary and all key secondary endpoints in the Phase III GLORY-2 trial targeting moderate-to-severe obesity in China. INNOVENT BIO plans to soon submit a new drug application for the 9mg dose of Mazdutide for adult weight management to regulators.