异动解读|Roivant Sciences盘中上涨14.2%,核心管线Mosliciguat二期临床达主要终点

行情直击
Sep 08

9月8日,Roivant Sciences盘中上涨14.2%,报39.9美元/股,成交额3711.26万美元。

消息面上,公司旗下Pulmovant部门宣布其吸入式sGC激活剂Mosliciguat在间质性肺病相关肺动脉高压(PH-ILD)患者中开展的二期PHocus研究达到主要及次要终点。数据显示,治疗16周后肺血管阻力经安慰剂校正降低56.3%,六分钟步行距离改善35.2米,NT-proBNP下降53.2%;在预设探索性分析中,24周时六分钟步行距离改善进一步扩大至52.7米,NT-proBNP降幅达75.9%。药物安全性良好,疗效持续改善。PH-ILD长期缺乏有效疗法,该数据为潜在突破。公司同时披露已启动Phrontier三期研究,推动Mosliciguat向注册阶段迈进。

Roivant Sciences是一家生物制药公司,核心管线包括处于FDA审查阶段的brepocitinib、靶向FcRn的IMVT-1402以及Mosliciguat。

(以上内容均基于市场公开消息,由程序或算法智能生成,仅作为股价异动提醒,不作为投资建议或交易依据。)

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