康方生物PD-1/VEGF双特异性抗体(AK112)Ia期临床进展

新浪港股
Nov 02, 2020
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  康方生物-B(09926-HK)公布,公司核心自主研发的新药PD-1/VEGF双特异性抗体(研发代号:AK112)Ia期临床研究阶段性数据已在2020中国肿瘤免疫治疗会议上发布。

  目前AK112已经在澳洲和中国开展Ia期临床研究,最初剂量递增阶段的临床研究结果令人鼓舞。本研究的结果显示,在有至少经历过一次肿瘤评估并对PD-1抑制剂不敏感或接受过PD-1抑制剂治疗的11例晚期实体瘤患者中,共有4例达到了缓解(客观缓解率(ORR):36 %),共7例肿瘤缩小且疾病稳定(疾病控制率(DCR):64%)。

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