JCR Pharmaceuticals (TYO:4552) and Modalis Therapeutics (TYO:4883) have validated the initial proof of concept for a novel gene therapy targeting a central nervous system (CNS) disease, according to a filing on Monday.
Building on this success, they have signed a new joint research agreement to conduct pre-clinical studies, read the filing.
The research will utilize JCR's J-Brain Cargo technology to cross the blood-brain barrier and Modalis' CRISPR-GNDM technology for gene modulation.
The goal is to develop an innovative gene therapy offering improved efficacy and safety through minimally invasive intravenous injection.
Modalis Therapeutics' shares gained nearly 7% at market close.
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