智通财经APP获悉,宜明昂科-B(01541)高开逾3%,截至发稿,涨3.7%,报4.77港元,成交额38.73万港元。
消息面上,宜明昂科-B发布公告,IMM2510联合化疗进行非小细胞肺癌(NSCLC)一线治疗的Ib/II期临床试验成功完成首例患者给药。安全性导入期后,公司计划在上述临床试验中招募一线患者,预计最早于2025年下半年发布初步临床数据,包括来自NSCLC一线患者的数据。
据介绍,IMM2510I期剂量递增研究的临床数据显示出令人鼓舞的疗效迹象:数名曾接受多种疗法失败的晚期实体瘤患者在接受IMM2510治疗后达到部分缓解(PR)。截至2024年12月31日,招募超过100名患者加入IMM2510单药治疗的I/II期临床试验。在多种实体瘤适应症(包括NSCLC、三阴性乳腺癌(TNBC)及软组织肉瘤(STS)等重复治疗失败的患者)中观察到良好的耐受性及有前景的初步PR信号。
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