European equities traded in the US as American depositary receipts were trending modestly lower late Tuesday morning, declining 0.26% to 1,416.22 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biopharmaceutical companies DBV Technologies (DBVT) and Cellectis (CLLS), which rose 5.1% each. They were followed by telecommunications operator Telefonica (TEF) and petroleum refiner Equinor (EQNR), which increased 1.8% each.

The decliners from continental Europe were led by accommodations booking company trivago (TRVG) and electronics conglomerate Philips (PHG), which fell 4.4% and 3.9% respectively. They were followed by furniture maker Natuzzi (NTZ) and pharmaceutical company Novo Nordisk (NVO), which dropped 3.4% and 3.1% respectively.

From the UK and Ireland, the gainers were led by pharmaceutical company Silence Therapeutics (SLN) and alcoholic beverage company Diageo (DEO), which were up 3.3% and 2.1% respectively. They were followed by financial services company Lloyds Banking Group (LYG) and tobacco company British American Tobacco (BTI), which advanced 1.3% and 1.1% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies NuCana (NCNA) and Bicycle Therapeutics (BCYC), which lost 68% and 4.3% respectively. They were followed by biotech firm Autolus Therapeutics (AUTL) and biopharmaceutical company Biodexa Pharmaceuticals (BDRX), which were down 3.8% and 2.8% respectively.