Ventyx Biosciences Inc., a clinical-stage biopharmaceutical company, has announced its financial results for the first quarter of 2025, highlighting a net loss of $27.4 million compared to a $38.6 million loss reported in the first quarter of 2024. Research and Development (R&D) expenses were reported at $22.9 million, a decrease from $33.7 million in the same period the previous year. General and Administrative (G&A) expenses also decreased to $7.2 million from $8.0 million. As of March 31, 2025, the company had cash, cash equivalents, and marketable securities totaling $228.8 million, which are expected to fund operations into at least the second half of 2026. In terms of operational progress, Ventyx Biosciences is advancing its Phase 2 studies for its NLRP3 inhibitors, VTX3232 and VTX2735, targeting neurodegenerative, cardiovascular, and metabolic indications. The company anticipates releasing key data from these studies throughout 2025, including a Q2 readout from the VTX3232 study in early Parkinson's disease patients and H2 readouts from studies involving recurrent pericarditis and obesity with cardiometabolic risk factors. Additionally, VTX958 has shown promising results in Crohn's disease, with discussions ongoing regarding further development opportunities.
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