5月14日,诺和诺德同意与Septerna共同开发和商业化用于治疗肥胖症和其他心脏代谢疾病的口服小分子药物,交易价值高达22亿美元。受该消息影响,Septerna盘前暴涨63%。
Septerna是一家临床阶段生物制药公司,专注于开发针对一类名为G蛋白偶联受体(GPCR)的细胞膜受体的治疗方法,其中包括GLP-1受体激动剂。作为交易的一部分,该公司将从诺和诺德获得超过2亿美元的预付款和近期里程碑付款。
诺和诺德向Septerna支付的总金额可能达到22亿美元,包括预付款以及研发和商业里程碑付款。此外,总部位于加州旧金山的Septerna将有权根据其上市产品的全球净销售额获得分层版税。
两家公司表示,根据协议条款,诺和诺德将承担合作项目的所有研发费用,包括针对GLP-1、GIP、胰高血糖素受体和其他GPCR靶点的四个初始开发项目。该协议预计将于2025年第二季度完成。
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