智通财经APP获悉,葛兰素史克(GSK.US)将以高达20亿美元的现金收购Boston Pharmaceuticals主要资产——治疗肝病的实验性药物efimosfermin alfa。葛兰素史克周三表示,Boston Pharmaceuticals开发的这种治疗方法已准备进入临床试验的最后阶段,有可能成为治疗一种脂肪肝疾病的一流药物。
由于一些顶级药物面临专利到期,人们担心与竞争对手相比,葛兰素史克的股票走势艰难,这家英国制药商正寻求支持其新药的研发。葛兰素史克表示,将为efimosfermin alfa药物预付12亿美元,并有可能额外支付总计8亿美元的分期付款。
药企对肝病疗法的兴趣日益浓厚,礼来(LLY.US)和诺和诺德(NVO.US)都在研究肝病的治疗方法。肝脏可能会因脂肪堆积或饮酒而受损,目前几乎没有治疗方案。尽管葛兰素史克购买的药物可能对这两种疾病都有疗效,但目前它还在研发中,用于治疗由脂肪堆积引起的损害(MASH肝炎)。efimosfermin alfa的中期试验数据显示,每月一次的注射剂量可迅速逆转肝纤维化并阻止其进展。
葛兰素史克表示,该交易显着扩大了公司的肝病产品线,旨在解决肝脏疾病的脂肪变性和病毒驱动因素,提供多种开发选择,并可能在2029年首次推出。
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