智通财经APP获悉，宜明昂科-B(01541)高开近10%，截至发稿，涨9.73%，报10.6港元，成交额351.28万港元。
消息面上，5月22日，宜明昂科和 Instil Bio, Inc.共同发布IMM2510/AXN-2510临床试验更新以及非小细胞肺癌(NSCLC)临床开发战略。宜明昂科预计将于2025年年底完成IMM2510联合化疗治疗一线非小细胞肺癌患者的II期临床试验入组(包括单药队列)，第三季度完成约60名患者入组工作。
宜明昂科预计将在2025年下半年分享该II期临床试验的初步安全性和有效性结果。客观响应率(ORR)与竞争对手处于类似开发阶段的PD-(L)1x血管内皮生长因子(VEGF)双特异性抗体的数据集相似，均为针对既往接受过治疗的NSCLC 患者，ORR为23%（可评估有效性n=13）。IMM2510/AXN-2510是一种PD-L1和VEGF的双特异性抗体，目前正开发用于治疗多种实体肿瘤癌症。
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