Autolus Therapeutics Announces Positive CHMP Opinion for Obecabtagene Autoleucel in Treatment of Relapsed or Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Reuters
23 May
Autolus <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Announces Positive CHMP Opinion for Obecabtagene Autoleucel in Treatment of Relapsed or Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Autolus Therapeutics plc, a biopharmaceutical company, has announced that the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use $(CHMP)$ has recommended the European Commission $(EC)$ approve obecabtagene autoleucel (obe-cel) for adult patients aged 26 and older with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (r/r B-ALL). This recommendation is based on the FELIX clinical trial, which demonstrated high response rates and low toxicity. The EC's decision on the conditional marketing authorization application is anticipated within two months, following the positive CHMP opinion. Obe-cel has already received approval from the U.S. Food and Drug Administration (FDA) in November 2024 and a conditional marketing authorization from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) in April 2025. The EC decision will be applicable to all 27 European Union Member States, Iceland, Norway, and Liechtenstein.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Autolus Therapeutics plc published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9457217-en) on May 23, 2025, and is solely responsible for the information contained therein.

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