智通财经APP获悉，摩根士丹利分析师Judah Frommer在美国生物技术公司Bicara Therapeutics(BCAX.US)公布Ficerafusp alfa的1/1b期临床试验中期数据后，维持对该股的“买入”评级，目标价保持在36美元。Ficerafusp alfa作为该公司的核心资产，是一款具有首创性的双功能抗体药物。
据了解，Bicara Therapeutics是一家专注于开发实体瘤创新疗法的临床阶段生物制药公司。其研发的Ficerafusp alfa旨在增强肿瘤渗透能力并克服免疫抑制性肿瘤微环境——这一直是制约实体瘤治疗效果的关键因素。
最新公布的1/1b期研究数据显示，该药物在治疗HPV阴性头颈部鳞状细胞癌患者方面展现出显著疗效。分析师特别指出，试验报告的中位总生存期超过20个月，完全缓解率达到18-21%。Frommer认为，这一数据相较标准治疗方案是重大突破，预示着Ficerafusp alfa有望在这一治疗难度较大的领域取得里程碑式进展。
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