AstraZeneca (AZN) said Sunday a phase 3 study of its camizestrant drug combined with another cancer medicine demonstrated a significant and meaningful improvement in progression-free survival in patients with a type of difficult-to-treat breast cancer.
The company said its combination therapy reduced the risk of disease progression or death by 56% compared with standard treatment, with patients experiencing a median progression-free survival of 16 months versus 9.2 months for standard-of-care treatment.
The drugmaker said its therapy also delayed quality-of-life deterioration and pain.
AstraZeneca said data for key secondary endpoints of time to second disease progression and overall survival were immature at the time of the interim analysis.