来源:药渡撰文:幻目 编辑:维他命分子胶(Molecular glues)是一种用于蛋白质调控的小分子,其作用机制是通过增强蛋白质之间的相互作用来调节蛋白质的功能和代谢。与传统的酶抑制剂或受体激动剂不同,分子胶的主要功能是通过促使蛋白质之间的结合,改变它们的构象或功能,从而影响细胞信号传导和代谢过程。分子胶是近年来备受关注的革命性药物开发策略。近年来,罗氏、诺和诺德、艾伯维、礼来等制药巨头...
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