智通财经APP获悉,6月7日,CDE官网显示,礼来(LLY.US)的GLP-1R/GIPR双重激动剂替尔泊肽新适应症申报已获受理,推测此次申报的适应症为阻塞性睡眠呼吸暂停。
据悉,阻塞性睡眠呼吸暂停(OSA)是一种与睡眠相关的呼吸障碍,其特征是睡眠时患者上呼吸道完全或部分塌陷,导致呼吸暂停或呼吸不足,并可能导致血氧饱和度降低和/或患者从睡眠中醒来。阻塞性睡眠呼吸暂停会导致严重的心脏代谢并发症,包括高血压、冠心病、中风、心力衰竭、心房颤动和2型糖尿病等。
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