金吾财讯 | 默沙东(MRK)盘前股价拉升,暂报80.37美元,涨1.77%。消息面上,公司今天宣布了三项 3 期临床试验中前两项的积极顶线结果,这些试验评估了恩利西肽癸酸酯的安全性和有效性。恩利西肽是一种在研口服前蛋白转化酶枯草杆菌蛋白酶/kexin 9 型 (PCSK9) 抑制剂,正在评估其用于治疗正在接受降脂疗法(包括至少一种他汀类药物)的高脂血症成人患者。CORALreef HeFH 和 CORALreef AddOn 试验成功达到了其主要终点和所有关键次要终点,表明与安慰剂(CORALreef HeFH)和其他口服非他汀类药物疗法(CORALreef AddOn)相比,恩利西肽在降低低密度脂蛋白胆固醇 (LDL-C) 方面具有统计学上和临床上显著的更高水平。
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